Budget Amount *help |
¥116,610,000 (Direct Cost: ¥89,700,000、Indirect Cost: ¥26,910,000)
Fiscal Year 2014: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2013: ¥23,400,000 (Direct Cost: ¥18,000,000、Indirect Cost: ¥5,400,000)
Fiscal Year 2012: ¥24,570,000 (Direct Cost: ¥18,900,000、Indirect Cost: ¥5,670,000)
Fiscal Year 2011: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2010: ¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
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Outline of Final Research Achievements |
We examined the associations of lipid mediators or their genetic polymorphysms with common diseases in inhabitants of Hisayama Town, Fukuoka. The association study of genetic polymorphisms and common diseases revealed that a polymorphism in PLA2G3 gene was associated with serum HDL cholesterol concentration, and a polymorphism in PA-PLA1 was correlated with body mass index. The cohort study in Hisayama demonstrated that a lower ratio of serum eicosapentaenoic acid to arachidonic acid was a risk factor for the development of coronary heart disease and death from malignant tumors, and that a decreased level of serum 1,25-dihydroxy-vitamin D was associated with an increased risk of chronic kidney disease.
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