| Budget Amount *help |
¥61,360,000 (Direct Cost: ¥47,200,000、Indirect Cost: ¥14,160,000)
Fiscal Year 2014: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
Fiscal Year 2013: ¥11,180,000 (Direct Cost: ¥8,600,000、Indirect Cost: ¥2,580,000)
Fiscal Year 2012: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2011: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2010: ¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
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| Outline of Final Research Achievements |
To elucidate molecular mechanism of plant drought and heat responses mediated by a transcription factor, DREB2A, we analyzed regulation of DREB2A gene expression under drought and heat stress conditions in Arabidopsis. We found that HsfA1-type transcription factors regulate the expression of this gene under heat stress and AREB-type transcription factors under drought stress conditions. Moreover, we identified GRF7 as a transcriptional repressor under control conditions. On the other hand, we also revealed that the stabilization of the DREB2A protein was important for its activation as post-translational regulation. Finally, we identified an Arabidopsis DPB3 homolog, DPB3-1, which interacts with DREB2A and found that DPB3-1 enhances heat stress-inducible gene expression during heat stress responses in cooperation with DREB2A.
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