| Budget Amount *help |
¥195,390,000 (Direct Cost: ¥150,300,000、Indirect Cost: ¥45,090,000)
Fiscal Year 2014: ¥36,790,000 (Direct Cost: ¥28,300,000、Indirect Cost: ¥8,490,000)
Fiscal Year 2013: ¥37,700,000 (Direct Cost: ¥29,000,000、Indirect Cost: ¥8,700,000)
Fiscal Year 2012: ¥38,350,000 (Direct Cost: ¥29,500,000、Indirect Cost: ¥8,850,000)
Fiscal Year 2011: ¥39,130,000 (Direct Cost: ¥30,100,000、Indirect Cost: ¥9,030,000)
Fiscal Year 2010: ¥43,420,000 (Direct Cost: ¥33,400,000、Indirect Cost: ¥10,020,000)
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| Outline of Final Research Achievements |
Neuro-vascular interactions have been found to play important roles in development of both neural networks and vascular networks. In particular, for the morphogenesis of neural crest cells, signals produced by the dorsal aorta are critical. In the central nervous system, the patterning of blood vessels is determined by differentiation states of neuronal cells in the spinal cord. We have also revealed a novel role of fibronectin in inter-tissue signaling. The findings obtained in this study open a new way for understanding how the neuro-vascular wiring is established and functions, which might also be applicable for other inter-tissue signaling.
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