Budget Amount *help |
¥86,710,000 (Direct Cost: ¥66,700,000、Indirect Cost: ¥20,010,000)
Fiscal Year 2015: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2014: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2013: ¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2012: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2011: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
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Outline of Final Research Achievements |
Our most important achievement is to show that a stereoisomer of natural products is most useful for tuning the target selectivity. Usually, natural product have plural target and functions as a multi-biofunctional molecule. natural product behave like a bunch of keys, not a canonical lock-and-key. We can reduce the side reactions in the body by using a stereoisomer of natural products. We demonstrated the successful example of target tuning of natural products in plant hormone mimicking natural product, coronatine.
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