| Budget Amount *help |
¥51,870,000 (Direct Cost: ¥39,900,000、Indirect Cost: ¥11,970,000)
Fiscal Year 2015: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Fiscal Year 2014: ¥11,050,000 (Direct Cost: ¥8,500,000、Indirect Cost: ¥2,550,000)
Fiscal Year 2013: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Fiscal Year 2012: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Outline of Final Research Achievements |
We developed a series of P-spiro chiral tetraaminophosphonium salts as organic molecular catalysts having a charge-assisted hydrogen-bonding ability. Their inherent abilities to exert four different, synthetically relevant asymmetric catalyses have been brought out through the unique molecular design on a single core structure, N4P+. These catalyses have been applied to the development of highly selective transformations, such as (1) an array of unusual conjugate additions which require multiple selectivity control, (2) a Payne-type oxidation of N-sulfonyl imines, (3) a reductive cross coupling of carbonyl compounds (formal pinacol coupling), and (4) a radical coupling reaction under photo-redox conditions.
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