|Budget Amount *help
¥119,470,000 (Direct Cost: ¥91,900,000、Indirect Cost: ¥27,570,000)
Fiscal Year 2015: ¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2014: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2013: ¥21,450,000 (Direct Cost: ¥16,500,000、Indirect Cost: ¥4,950,000)
Fiscal Year 2012: ¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2011: ¥41,730,000 (Direct Cost: ¥32,100,000、Indirect Cost: ¥9,630,000)
|Outline of Final Research Achievements
Aiming to develop high-speed closed system for analysis and isolation of rare cell populations within the blood, in this study, we showed the possibility that could detect rare cell populations in blood by the viscoelastic difference (difference in passing time through the microfluidic channel) of the cell. It will be possible to analyze erythroblasts or circulating cancer cells in peripheral blood at high speed while they are in an extra corporeal circulation. Therefor, prenatal diagnosis or prognostic prediction of cancer will be available more easily and exactly by this system.
We successfully achieved in vitro generation of platelets from human pluripotent stem cell derived MKs by a two dimensional flow culture that recapitulates bone marrow blood flow.