Budget Amount *help |
¥108,810,000 (Direct Cost: ¥83,700,000、Indirect Cost: ¥25,110,000)
Fiscal Year 2015: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2014: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2013: ¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2012: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2011: ¥33,020,000 (Direct Cost: ¥25,400,000、Indirect Cost: ¥7,620,000)
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Outline of Final Research Achievements |
Strong reciprocal natural selection between a host plant and a pathogen leaves DNA signatures on the genomes of respective organisms. By employing whole genome sequencing and detecting DNA signatures of selection, we succeeded in isolating two rice resistance (R-) genes (Pia and Pii) and three Magnaporthe oryzae avirulence effector (AVR) genes (AVR-Pia, AVR-Pii, AVR-Pik). Molecular interactions between rice R-protein Pik and Magnaporthe AVR-Pik revealed that their genes are coevolving. We also have developed a series of methods including MutMap and QTL-seq to quickly detect selection signature by whole genome resequencing.
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