| Budget Amount *help |
¥97,760,000 (Direct Cost: ¥75,200,000、Indirect Cost: ¥22,560,000)
Fiscal Year 2015: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2014: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2013: ¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2012: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2011: ¥21,970,000 (Direct Cost: ¥16,900,000、Indirect Cost: ¥5,070,000)
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| Outline of Final Research Achievements |
Primary endosymbiosis, in which bacteria enter (pre-)eukaryotic cells and finally became mitochondria and chloroplasts, plays a critical role in eukaryogenesis. Even today, bacterial invasion into eukaryotic cells takes place every day at sites of infection. In this study, we focused on the relationship between various kinds of intracellular pathogenic/environmental bacteria and their eukaryotic host cells including free-living Acanthamoeba and human cells. We concluded several mechanistic principles which drive the first step of matryoshka-type evolution.
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