|Budget Amount *help
¥96,200,000 (Direct Cost: ¥74,000,000、Indirect Cost: ¥22,200,000)
Fiscal Year 2015: ¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000)
Fiscal Year 2014: ¥14,430,000 (Direct Cost: ¥11,100,000、Indirect Cost: ¥3,330,000)
Fiscal Year 2013: ¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2012: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2011: ¥29,250,000 (Direct Cost: ¥22,500,000、Indirect Cost: ¥6,750,000)
|Outline of Final Research Achievements
To investigate neuronal mechanisms of transitive inference, we recorded single unit activities from the lateral prefrontal cortex (LPFC) and caudate nucleus (Cd) of macaque monkeys while they performed a reward inference task. We found that prefrontal neurons, not basal ganglia neurons, coded the categorical information, which was shown to have a close relation to the ability of transitive inference.
Also, we applied the DREADDs (the Designer Receptors Exclusively Activated by the Designer Drugs) technique to suppress the information transmission in the bilateral LPFC-Cd pathway in the macaque brain. Results suggest that the decrease in the signal transmission in the pathway led to the increase in the discount factor for the trial outcome.