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Neural basis of intuitive and deliberative decision-making impairments in neuropsychiatric disorders

Planned Research

Project AreaElucidation of neural computation for prediction and decision making: toward better human understanding and applications
Project/Area Number 23120009
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionKyoto University

Principal Investigator

Takahashi Hidehiko  京都大学, 医学(系)研究科(研究院), 准教授 (60415429)

Co-Investigator(Kenkyū-buntansha) MIMURA Masaru  慶応義塾大学, 医学部, 教授 (00190728)
KATO Motoichiro  慶応義塾大学, 医学部, 教授 (80161123)
SUHRA Tetsuya  放射線医学総合研究所, 脳機能イメージング研究部, 部長 (90216490)
Project Period (FY) 2011-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥90,220,000 (Direct Cost: ¥69,400,000、Indirect Cost: ¥20,820,000)
Fiscal Year 2015: ¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2014: ¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2013: ¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2012: ¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2011: ¥21,970,000 (Direct Cost: ¥16,900,000、Indirect Cost: ¥5,070,000)
Keywords意思決定 / 精神疾患 / 神経科学 / 精神・神経疾患 / 情動 / 神経伝達物質 / 脳画像
Outline of Final Research Achievements

We investigated the relationship between noradrenaline transporter (NET) in the brain measured by PET and the degree of loss aversion assessed with an economic experiment in healthy control. We found that individuals with high density of thalamic NET tend to show reckless decision-making (low loss aversion). However, when it comes to gambling disorder patients, there were two subtypes in terms of loss aversion (low and high loss aversion groups). High loss aversion group showed cautious decision-making, which was counterintuitive. High loss aversion group showed differential brain volume reduction in the orbitofrontal cortex. The findings suggest that treatment for gamble disorders should be provided depending on the subtype.

Report

(6 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • Research Products

    (101 results)

All 2016 2015 2014 2013 2012 2011 Other

All Int'l Joint Research (4 results) Journal Article (51 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 51 results,  Open Access: 19 results,  Acknowledgement Compliant: 13 results) Presentation (45 results) (of which Int'l Joint Research: 2 results,  Invited: 44 results) Book (1 results)

  • [Int'l Joint Research] カリフォルニア工科大学/コロンビア大学/ブラウン大学(米国)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] ザグレブ大学(クロアチア)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] ユトレヒト大学(オランダ)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] ユニバーシティ カレッジ ロンドン/ケンブリッジ大学(英国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Multimodal neuroimaging as a window into the pathological physiology of schizophrenia: Current trends and issues.2016

    • Author(s)
      Isobe M, Miyata J, Hazama M, Fukuyama H, Murai T, Takahashi H.
    • Journal Title

      Neurosci Res.

      Volume: 102 Pages: 29-38

    • DOI

      10.1016/j.neures.2015.07.009

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Heterogeneity of Loss Aversion in Pathological Gambling.2015

    • Author(s)
      Takeuchi H, Kawada R, Tsurumi K, Yokoyama N, Takemura A, Murao T, Murai T, Takahashi H.
    • Journal Title

      J Gambl Stud.

      Volume: 印刷中

    • NAID

      120005997647

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Insular Gray Matter Volume and Objective Quality of Life in Schizophrenia.2015

    • Author(s)
      Uwatoko T, Yoshizumi M, Miyata J, Ubukata S, Fujiwara H, Kawada R, Kubota M, Sasamoto A, Sugihara G, Aso T, Urayama S, Fukuyama H, Murai T, Takahashi H.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 11 Pages: e0142018-e0142018

    • DOI

      10.1371/journal.pone.0142018

    • NAID

      120005743645

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Polymorphism of the Oxytocin Receptor Gene Modulates Behavioral and Attitudinal Trust among Men but Not Women.2015

    • Author(s)
      Nishina K, Takagishi H, Inoue-Murayama M, Takahashi H, Yamagishi T.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 10 Pages: 0137089-0137089

    • DOI

      10.1371/journal.pone.0137089

    • NAID

      120005763421

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Discrepancy between explicit judgement of agency and implicit feeling of agency: Implications for sense of agency and its disorders.2015

    • Author(s)
      Saito N, Takahata K, Murai T, Takahashi H.
    • Journal Title

      Conscious Cogn.

      Volume: 印刷中 Pages: 1-7

    • DOI

      10.1016/j.concog.2015.07.011

    • NAID

      120005674593

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Creativity and positive symptoms in schizophrenia revisited: Structural connectivity analysis with diffusion tensor imaging2015

    • Author(s)
      Son et al.
    • Journal Title

      Schizophrenia Research

      Volume: in press Issue: 1-3 Pages: 221-6

    • DOI

      10.1016/j.schres.2015.03.009

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] A Small Number of Abnormal Brain Connections Predicts Adult Autism Spectrum Disorder.2015

    • Author(s)
      .Yahata N, Morimoto J, Hashimoto R, Lisi G, Shibata K, Kawakubo Y, Kuwabara H, Kuroda M, Yamada T, Megumi F, Imamizu H, Náñez J, Takahashi H, Okamoto Y, Kasai K, Kato N, Sasaki Y, Watanabe T, Kawato M
    • Journal Title

      Nat. Commun.

      Volume: 7 Issue: 1 Pages: 11254-11254

    • DOI

      10.1038/ncomms11254

    • NAID

      120005770754

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Behavioral evidence of delayed prediction signals during agency attribution in patients with schizophrenia.2015

    • Author(s)
      Koreki, A., Maeda, T., Fukushima, H., Umeda, S., Takahata, K., Okimura, T., Funayama, M., Iwashita, S., Mimura, M., & Kato, M. (2015)
    • Journal Title

      Psychiatry Research

      Volume: 230 Issue: 1 Pages: 78-83

    • DOI

      10.1016/j.psychres.2015.08.023

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Simulation of the capacity and precision of working memory in the hypodoparminergic state: relevance to schizophrenia.2015

    • Author(s)
      T. Okimura, S. Tanaka, T. Maeda, M. Kato, and M. Mimura
    • Journal Title

      Neuroscience

      Volume: 295 Pages: 80-89

    • DOI

      10.1016/j.neuroscience.2015.03.039

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Optogenetic Activation of CA1 Pyramidal Neurons at the Dorsal and Ventral Hippocampus Evokes Distinct Brain-Wide Responses Revealed by Mouse fMRI.2015

    • Author(s)
      N, Yoshida K, Komaki Y, Xu M, Sakai Y, Hikishima K, Mimura M, Okano H, Tanaka KF.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 3 Pages: e0121417-e0121417

    • DOI

      10.1371/journal.pone.0121417

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Are ambiguity aversion and ambiguity intolerance identical? A neuroeconomics investigation.2015

    • Author(s)
      Tanaka Y, Fujino J, Ideno T, Okubo S, Takemura K, Miyata J, Kawada R, Fujimoto S, Kubota M, Sasamoto A, Hirose K, Takeuchi H, Fukuyama H, Murai T, Takahashi H.
    • Journal Title

      Front Psychol.

      Volume: 5 Pages: 1550-1550

    • DOI

      10.3389/fpsyg.2014.01550

    • NAID

      120005756280

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Visual processing and social cognition in schizophrenia: relationships among eye movements, biological motion perception, and empathy.2015

    • Author(s)
      Matsumoto Y, Takahashi H, Murai T, Takahashi H.
    • Journal Title

      Neurosci Res.

      Volume: 90 Pages: 95-100

    • DOI

      10.1016/j.neures.2014.10.011

    • NAID

      120005555508

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Anterior cingulate volume predicts response to cognitive behavioral therapy in major depressive disorder.2015

    • Author(s)
      Fujino J, Yamasaki N, Miyata J, Sasaki H, Matsukawa N, Takemura A, Tei S, Sugihara G, Aso T, Fukuyama H, Takahashi H, Inoue K, Murai T.
    • Journal Title

      J Affect Disord.

      Volume: 174 Pages: 397-9

    • DOI

      10.1016/j.jad.2014.12.009

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reflected glory and failure: the role of the medial prefrontal cortex and ventral striatum in self vs other relevance during advice-giving outcomes.2015

    • Author(s)
      Mobbs D, Hagan CC, Yu R, Takahashi H, FeldmanHall O, Calder AJ, Dalgleish T.
    • Journal Title

      Soc Cogn Affect Neurosci.

      Volume: 未定

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional relevance of the precuneus in verbal politeness.2015

    • Author(s)
      Ashizuka A, Mima T, Sawamoto N, Aso T, Oishi N, Sugihara G, Kawada R, Takahashi H, Murai T, Fukuyama H.
    • Journal Title

      Neurosci Res.

      Volume: 91 Pages: 48-56

    • DOI

      10.1016/j.neures.2014.10.009

    • NAID

      120005593691

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fiber tract associated with autistic traits in healthy adults.2014

    • Author(s)
      Hirose K, Miyata J, Sugihara G, Kubota M, Sasamoto A, Aso T, Fukuyama H, Murai T, Takahashi H.
    • Journal Title

      J Psychiatr Res.

      Volume: 59 Pages: 117-24

    • DOI

      10.1016/j.jpsychires.2014.09.001

    • NAID

      120005512271

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Insular activation during reward anticipation reflects duration of illness in abstinent pathological gamblers.2014

    • Author(s)
      Tsurumi K, Kawada R, Yokoyama N, Sugihara G, Sawamoto N, Aso T, Fukuyama H, Murai T, Takahashi H.
    • Journal Title

      Front Psychol.

      Volume: 5 Pages: 1013-1013

    • DOI

      10.3389/fpsyg.2014.01013

    • NAID

      120005496639

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The contribution of cortical thickness and surface area to gray matter asymmetries in the healthy human brain2014

    • Author(s)
      Koelkebeck K, Miyata J, Kubota M, Kohl W, Son S, Fukuyama H, Sawamoto N, Takahashi H, Murai T.
    • Journal Title

      Hum Brain Mapp.

      Volume: 35 Issue: 12 Pages: 6011-22

    • DOI

      10.1002/hbm.22601

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Altered brain response to others' pain in major depressive disorder.2014

    • Author(s)
      Fujino J, Yamasaki N, Miyata J, Kawada R, Sasaki H, Matsukawa N, Takemura A, Ono M, Tei S, Takahashi H, Aso T, Fukuyama H, Murai T.
    • Journal Title

      J Affect Disord.

      Volume: 165 Pages: 170-5

    • DOI

      10.1016/j.jad.2014.04.058

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Modafinil augments brain activation associated with reward anticipation in the nucleus accumbens.2014

    • Author(s)
      Funayama, T., Ikeda, Y., Tateno, A., Takahashi, H., Okubo, Y., Fukuyama, H., & Suzuki, H.
    • Journal Title

      Psychopharmacology

      Volume: 231 Issue: 16 Pages: 3217-3228

    • DOI

      10.1007/s00213-014-3499-0

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cognitive neuroscience of social emotions and implications for psychopathology: Examining embarrassment, guilt, envy, and schadenfreude.2014

    • Author(s)
      Jankowski, K. F., & Takahashi, H.
    • Journal Title

      Psychiatry and clinical neuroscience

      Volume: 68 Issue: 5 Pages: 319-336

    • DOI

      10.1111/pcn.12182

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Norepinephrine transporter occupancy by nortriptyline in patients with depression: a positron emission tomography study with (S,S)-[¹⁸F]FMeNER-D₂.2014

    • Author(s)
      Takano H, Arakawa R, Nogami T, Suzuki M, Nagashima T, Fujiwara H, Kimura Y, Kodaka F, Takahata K, Shimada H, Murakami Y, Tateno A, Yamada M, Ito H, Kawamura K, Zhang MR, Takahashi H, Kato M, Okubo Y, Suhara T.
    • Journal Title

      Int J Neuropsychopharmacol.

      Volume: 17 Issue: 04 Pages: 553-60

    • DOI

      10.1017/s1461145713001521

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Can we predict burnout severity from empathy-related brain activity?2014

    • Author(s)
      Tei S, Becker C, Kawada R, Fujino J, Jankowski KF, Sugihara G, Murai T, Takahashi H.
    • Journal Title

      Transl Psychiatry.

      Volume: 4 Issue: 6 Pages: e393-e393

    • DOI

      10.1038/tp.2014.34

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Enhanced visual artistry and high accuracy of visual numerosity representation after left prefrontal damage2014

    • Author(s)
      Keisuke Takahata, Fumie Saito, Taro Muramatsu, Makiko Yamada, Joichiro Shirahase, Hajime Tabuchi1, Tetsuya Suhara, Masaru Mimura, Motoichiro Kato
    • Journal Title

      Neuropsychologia

      Volume: 57 Pages: 28-49

    • DOI

      10.1016/j.neuropsychologia.2014.02.022

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modafinil augments brain activation associated with reward anticipation in the nucleus accumbens.2014

    • Author(s)
      Funayama T, Ikeda Y, Tateno A, Takahashi H, Okubo Y, Fukayama H, Suzuki H
    • Journal Title

      Psychopharmacology (Berl)

      Volume: 印刷中

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Abnormal white matter integrity in the corpus callosum among smokers: tract-based spatial statistics.2014

    • Author(s)
      Umene-Nakano W, Yoshimura R, Kakeda S, Watanabe K, Hayashi K, Nishimura J, Takahashi H, Moriya J, Ide S, Ueda I, Hori H, Ikenouchi-Sugita A, Katsuki A, Atake K, Abe O, Korogi Y, Nakamura J.
    • Journal Title

      PLoS One.

      Volume: 9(2) Issue: 2 Pages: e87890-e87890

    • DOI

      10.1371/journal.pone.0087890

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impaired empathic abilities and reduced white matter integrity in schizophrenia.2014

    • Author(s)
      Fujino, J., Takahashi, H., Miyata, J., Sugihara, G., Kubota, M., Sasamoto, A., Fujiwara, H., Aso, T., Fukuyama, H., & Murai, T.
    • Journal Title

      Progress in Neuropsychopharmacology & Biological Psychiatry

      Volume: 48 Pages: 117-123

    • DOI

      10.1016/j.pnpbp.2013.09.018

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Global association between cortical thinning and white matter integrity reduction in schizophrenia.2014

    • Author(s)
      Sasamoto, A., Miyata, J., Kubota, M., Hirao, K., Kawada, R., Fujimoto, S., Tanaka, Y., Hazama, M., Sugihara, G., Sawamoto, N., Fukuyama, H., Takahashi, H., & Murai, T.
    • Journal Title

      Schizophrenia Bulletin

      Volume: 40 Issue: 2 Pages: 420-427

    • DOI

      10.1093/schbul/sbt030

    • NAID

      120005619771

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Increased l1 retrotransposition in the neuroral genome in schizophrenia.2014

    • Author(s)
      Miki Bundo, Manabu Toyoshima, Yohei Okada, Wado Akamatsu, Junko Ueda, Taeko Nemoto-Miyauchi, Fumiko Sunaga, Michihiro Toritsuka, Daisuke Ikawa, Akiyoshi Kakita, Motoichiro Kato, Kiyoto Kasai, Toshifumi Kishimoto, Hiroyuki Nawa, Hideyuki Okano, Takeo Yoshikawa, Tadafumi Katoemail, Kazuya Iwamoto
    • Journal Title

      Neuron

      Volume: 81 Issue: 2 Pages: 306-313

    • DOI

      10.1016/j.neuron.2013.10.053

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The neural mechanism of encountering misjudgment by the justice system.2013

    • Author(s)
      Cui, Q., Zhang, Q., & Takahashi, H.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 9 Pages: e75434-e75434

    • DOI

      10.1371/journal.pone.0075434

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] PET neuroimaging of extrastriatal dopamine receptors and prefrontal cortex function.2013

    • Author(s)
      Takahashi, H.
    • Journal Title

      Journal of Physiology Paris

      Volume: 107 Issue: 6 Pages: 503-509

    • DOI

      10.1016/j.jphysparis.2013.07.001

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Superiority illusion arises from resting-state brain network modulated by dopamine.2013

    • Author(s)
      Yamada, M., Uddin, L. Q., Takahashi, H., Kimura, Y., Takahata, K., Kousa, R., Ikoma, Y., Eguchi, Y., Takano, H., Ito, H., Higuchi, M., & Suhara, T.
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 110 Issue: 11 Pages: 4363-4367

    • DOI

      10.1073/pnas.1221681110

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular neuroimaging of emotional decision-making.2013

    • Author(s)
      Takahashi, H.
    • Journal Title

      Neuroscience Research

      Volume: 75 Issue: 4 Pages: 269-274

    • DOI

      10.1016/j.neures.2013.01.011

    • NAID

      130005395467

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regional gray matter reduction correlates with subjective quality of life in schizophrenia.2013

    • Author(s)
      Ubukata S, Miyata J, Yoshizumi M, Uwatoko T, Hirao K, Fujiwara H, Kawada R, Fujimoto S, Tanaka Y, Kubota M, Sasamoto A, Sawamoto N, Fukuyama H, Takahashi H, Murai T.
    • Journal Title

      J Psychiatr Res

      Volume: 47(4) Pages: 548-54

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of gray matter reductions on theory of mind abilities in patients with schizophrenia.2013

    • Author(s)
      Koelkebeck, K., Hirao, K., Miyata, J., Kawada, R., Saze, T., Dannlowski, U., Ubukata, S., Ohrmann, P., Bauer, J., Pedersen, A., Fukuyama, H., Sawamoto, N., Takahashi, H., & Murai, T.
    • Journal Title

      Social Neuroscience

      Volume: 8 Issue: 6 Pages: 631-639

    • DOI

      10.1080/17470919.2013.837094

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Cerebral responses to vocal attractiveness and auditory hallucinations in schizophrenia: a functional MRI study.2013

    • Author(s)
      Koeda M, Takahashi H, Matsuura M, Asai K, Okubo Y.
    • Journal Title

      Front Hum Neurosci

      Volume: 7 Pages: 221-221

    • DOI

      10.3389/fnhum.2013.00221

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activeness Improves Cognitive Performance in Human-Machine Interaction2013

    • Author(s)
      Yusuke Tamura, Mami Egawa, Shiro Yano, Takaki Maeda, Motoichiro Kato, and Hajime Asama
    • Journal Title

      Journal of Advanced Computational Intelligence and Intelligent Informatics

      Volume: 17(3) Pages: 425-432

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural substrates for judgment of self-agency in ambiguous situations2013

    • Author(s)
      Hirokata Fukushima, Yurie Goto, Takaki Maeda, Motoichiro Kato, and Satoshi Umeda
    • Journal Title

      PLoS One

      Volume: 8(8) Issue: 8 Pages: e72267-e72267

    • DOI

      10.1371/journal.pone.0072267

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced sense of agency in chronic residual schizophrenia with predominant negative symptoms.2013

    • Author(s)
      Takaki Maeda, Keisuke Takahata, Taro Muramatsu, Tsukasa Okimura, Akihiro Koreki,,Satoru Iwashita, Masaru Mimura, and Motoichiro Kato
    • Journal Title

      Psychiatry Research

      Volume: 209(3) Issue: 3 Pages: 386-392

    • DOI

      10.1016/j.psychres.2013.04.017

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Progression of logopenic variant primary progressive aphasia to apraxia and semantic memory deficits2013

    • Author(s)
      Michitaka Funayama, Yoshitaka Nakagawa, Yoko Yamaya, Fumihiro Yoshino, Masaru Mimura, Motoichiro Kato
    • Journal Title

      BMC Neurology

      Volume: 13 Issue: 1 Pages: 158-158

    • DOI

      10.1186/1471-2377-13-158

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Thalamocortical disconnection in the orbitofrontal region associated with cortical thinning in schizophrenia.2013

    • Author(s)
      Kubota, M., Miyata, J., Sasamoto, A., Sugihara, G., Yoshida, H., Kawada, R., Fujimoto, S., Tanaka, Y., Sawamoto, N., Fukuyama, H., Takahashi, H., & Murai, T.
    • Journal Title

      JAMA Psychiatry

      Volume: 70 Issue: 1 Pages: 12-21

    • DOI

      10.1001/archgenpsychiatry.2012.1023

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Acute NK1 receptor antagonist administration affects reward incentive anticipation processing in healthy volunteers.2013

    • Author(s)
      Kanako Saji
    • Journal Title

      Kanako Saji

      Volume: 印刷中

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Norepinephrine in the brain is associated with aversion to financial loss2013

    • Author(s)
      Takahashi, H., Fujie, S., Camerer, C., Arakawa, R., Takano, H., Kodaka, F., Matsui, H., Ideno T, Okubo S, Takemura K., Yamada M, Eguchi Y, Murai T, Okubo Y, Kato M,Ito H, Suhara T
    • Journal Title

      Molecular Psychiatry

      Volume: 18 Issue: 1 Pages: 3-4

    • DOI

      10.1038/mp.2012.7

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] It's not my fault: postdictive modulation of intentional binding by monetary gains and losses.2012

    • Author(s)
      Takahata, K.
    • Journal Title

      Plos One

      Volume: 7 Issue: 12 Pages: e53421-e53421

    • DOI

      10.1371/journal.pone.0053421

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of cooperation level of group on punishment for non-cooperators: a functional magnetic resonance imaging study.2012

    • Author(s)
      Fumitaka Kodaka
    • Journal Title

      PLoS One.

      Volume: 7 Issue: 7 Pages: e41338-e41338

    • DOI

      10.1371/journal.pone.0041338

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural circuits in the brain that are activated when mitigating criminal sentences2012

    • Author(s)
      Yamada M, Camerer CF, Fujie S, Kato M, Matsuda T, Takano H, Ito H, Suhara T, Takahashi H.
    • Journal Title

      Nature Communications

      Volume: 3(759) Issue: 1 Pages: 1-6

    • DOI

      10.1038/ncomms1757

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Honesty mediates the relationship between serotonin and reaction to unfairness2012

    • Author(s)
      Takahashi,H., Takano,H. ,Camerer,C., Ideno,T., Okubo,S., Matsui,H., Tamari,Y., Takemura,K., Arakawa,R., Kodaka,F., Yamada,M., Eguchi,Y., Murai,T., Okubo,Y., Kato,M., Ito,H., Suhara,T
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 109(11) Issue: 11 Pages: 4281-4284

    • DOI

      10.1073/pnas.1118687109

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of contact with schizophrenia on implicit attitudes towards schizophrenia patients held by clinical residents2012

    • Author(s)
      Omori A, Tateno A, Ideno T, Takahashi H, Kawashima Y, Takemura K, Okubo Y.
    • Journal Title

      BMC Psychiatry

      Volume: 12 Issue: 1 Pages: 205-205

    • DOI

      10.1186/1471-244x-12-205

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alexithymia and reduced white matter integrity in schizophrenia: a diffusion tensor imaging study on impaired emotional self-awareness.2012

    • Author(s)
      Kubota M, Miyata J, Sasamoto A, Kawada R, Fujimoto S, Tanaka Y, Sawamoto N, Fukuyama H, Takahashi H, Murai T.
    • Journal Title

      Schizophrnia Research

      Volume: 141 Issue: 2-3 Pages: 137-143

    • DOI

      10.1016/j.schres.2012.08.026

    • NAID

      120004874003

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Monoamines and assessment of risks.2012

    • Author(s)
      Hidehiko Takahashi
    • Journal Title

      Curr Opin Neurobiol.

      Volume: 22 Issue: 6 Pages: 1062-1067

    • DOI

      10.1016/j.conb.2012.06.003

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional significance of central D1 receptors in cognition: beyond working memory.2012

    • Author(s)
      Hidehiko Takahashi
    • Journal Title

      J Cereb Blood Flow Metab.

      Volume: 32 Issue: 7 Pages: 1248-1258

    • DOI

      10.1038/jcbfm.2011.194

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 依存症の分子神経イメージング2016

    • Author(s)
      高橋 英彦
    • Organizer
      関西核医学研究会
    • Place of Presentation
      大阪
    • Year and Date
      2016-03-12
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 柔軟な意思決定とその障害の神経機構の理解を目指して2016

    • Author(s)
      高橋 英彦
    • Organizer
      さきがけ「脳情報の解読と制御」研究成果報告会 特別講演
    • Place of Presentation
      東京
    • Year and Date
      2016-02-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Temporal-parietal junction as a domain-general source of cognitive flexibility.2016

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      The Third CiNet Conference
    • Place of Presentation
      Suita
    • Year and Date
      2016-02-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Nosology and precision psychiatry in the era of DSM5 and RdoC2015

    • Author(s)
      高橋 英彦
    • Organizer
      日本脳科学関連学会連合シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-11-29
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Flexible modulation of risk attitude during decision-making under ”quota” and its impairments in gambling disorders.2015

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      International Symposium on Prediction and Decision Making
    • Place of Presentation
      Tokyo
    • Year and Date
      2015-10-31
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 情動的意思決定の神経イメージング:神経経済学の新たな潮流2015

    • Author(s)
      高橋 英彦
    • Organizer
      ニューロエコノミクスセミナー
    • Place of Presentation
      東京
    • Year and Date
      2015-10-29
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 脳機能画像から見た感情の分析2015

    • Author(s)
      高橋 英彦
    • Organizer
      第41回人間ドック健診認定医・専門医研修会
    • Place of Presentation
      神戸
    • Year and Date
      2015-09-27
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] ギャンブル依存における脳画像と薬物治療の可能性2015

    • Author(s)
      高橋 英彦
    • Organizer
      ギャンブル依存症研修会
    • Place of Presentation
      横須賀
    • Year and Date
      2015-09-17
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 社会的情動の認知神経科学2015

    • Author(s)
      高橋 英彦
    • Organizer
      第23回日本感情心理学会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-14
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] MRI/PETの可能性2015

    • Author(s)
      高橋 英彦
    • Organizer
      日本脳科学関連学会連合将来構想委員会勉強会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-07
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 社会脳と精神医学2015

    • Author(s)
      高橋 英彦
    • Organizer
      第111回日本精神神経学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-06-04
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 情動的意思決定の神経イメージング:神経経済学の新たな潮流2015

    • Author(s)
      高橋 英彦
    • Organizer
      第29回日本医学会総会 2015 関西
    • Place of Presentation
      京都
    • Year and Date
      2015-04-11
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Sunny sideとdark sideの情動と意思決定の脳科学2015

    • Author(s)
      高橋 英彦
    • Organizer
      東京眼科アカデミー
    • Place of Presentation
      東京
    • Year and Date
      2015-02-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 情動的意思決定の神経イメージング:神経経済学の新たな潮流2014

    • Author(s)
      高橋 英彦
    • Organizer
      応用脳科学アカデミー
    • Place of Presentation
      東京
    • Year and Date
      2014-11-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 病的賭博の脳イメージング2014

    • Author(s)
      高橋 英彦
    • Organizer
      第36回生物学的精神医学会/第57回日本神経化学大会
    • Place of Presentation
      奈良
    • Year and Date
      2014-09-29 – 2014-09-30
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 「他人の不幸は蜜の味」の脳内過程-ポジティブサイコロジー2014

    • Author(s)
      高橋 英彦
    • Organizer
      第14回抗加齢医学の実際
    • Place of Presentation
      東京
    • Year and Date
      2014-09-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 高次脳機能検査 検査法と評価2014

    • Author(s)
      加藤元一郎
    • Organizer
      第15回日本早期認知症学術大会
    • Place of Presentation
      佐倉
    • Year and Date
      2014-09-12 – 2014-09-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Can we predict burnout among medical professionals from empathy-related brain activity?2014

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 意思決定と神経伝達物質2014

    • Author(s)
      高橋 英彦
    • Organizer
      第6回抗加齢内分泌研究会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 「精神科ベッドサイドの神経心理学」:注意障害2014

    • Author(s)
      加藤元一郎
    • Organizer
      第110回日本精神神経学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-06-26 – 2014-06-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Understanding and defining phenotype of psychiatric disorders.2014

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      Japanese-French Frontiers of Science Symposium
    • Place of Presentation
      Metz
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Molecular neuroimaging of emotional decision-making.2013

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      International Symposium on Prediction and Decision Making
    • Place of Presentation
      Kyoto
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Molecular neuroimaging of emotional decision-making2013

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      The Third International Symposium on "The Biology of Decision Making"
    • Place of Presentation
      Paris
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Effects of sport participation on social brain in schizophrenia.2013

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      3rd Asian Conference on Schizophrenia Research
    • Place of Presentation
      Bali
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] fMRI を用いた社会的情動・意思決定の神経基盤2013

    • Author(s)
      高橋 英彦
    • Organizer
      北海道大学脳科学研究教育センターシンポジウム
    • Place of Presentation
      札幌
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] fMRI を用いた社会的情動・意思決定の神経基盤2013

    • Author(s)
      高橋 英彦
    • Organizer
      大阪大学・玉川大学GCOE合同ワークショップ
    • Place of Presentation
      名古屋
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 脳が行う意思決定の不思議 ~行動や脳機能画像を解析してわかること2013

    • Author(s)
      高橋 英彦
    • Organizer
      奈良女子大学附属中等教育学校 Super science high school サイエンス先端講座
    • Place of Presentation
      奈良
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Molecular Imaging of emotional decision making2013

    • Author(s)
      高橋 英彦
    • Organizer
      京都大学霊長類研究所共同利用研究会
    • Place of Presentation
      犬山
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Molecular neuroimaging of prefrontal functions.2012

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      International conference on prefrontal cortex
    • Place of Presentation
      Kyoto
    • Year and Date
      2012-11-29
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Molecular neuroimaging of emotional decision-making.2012

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      Korean Society for Brain and Neural Science conference
    • Place of Presentation
      Seoul
    • Year and Date
      2012-09-25
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Molecular neuroimaging of emotional decision-making.2012

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      International conference on Complex Medical Engineering
    • Place of Presentation
      Kobe
    • Year and Date
      2012-07-01
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Molecular neuroimaging of emotional decision-making.2012

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      Annual International "Stress and Behavior" Neuroscience and Biopsychiatry Conference
    • Place of Presentation
      St. Petersburg
    • Year and Date
      2012-05-16
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 社会的情動の認知神経科学2012

    • Author(s)
      高橋 英彦
    • Organizer
      日本思春期青年期精神医学会
    • Place of Presentation
      広島
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Molecular Imaging of emotional decision making2012

    • Author(s)
      高橋 英彦
    • Organizer
      包括脳夏のワークショップ
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Monoamine and decision making under risk2012

    • Author(s)
      高橋 英彦
    • Organizer
      日本神経科学会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Molecular Imaging of emotional decision making2012

    • Author(s)
      高橋 英彦
    • Organizer
      日本心理学会
    • Place of Presentation
      川崎
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] リスク下の意思決定とモノアミン2012

    • Author(s)
      高橋 英彦
    • Organizer
      生理学研究所研究会
    • Place of Presentation
      岡崎
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 依存症の脳生理と分子イメージング2012

    • Author(s)
      高橋 英彦
    • Organizer
      東京大学医科学研究所GCOE 第五回疾患医科学ミニシンポジウム
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 情動的意思決定の脳科学2011

    • Author(s)
      高橋英彦
    • Organizer
      第3回医学教育シンポジウム
    • Place of Presentation
      東京(銀座ルノアール貸会議室)(招待講演)
    • Year and Date
      2011-12-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] ドーパミンの基礎的知見から統合失調症の症状を考えてみよう

    • Author(s)
      高橋 英彦
    • Organizer
      脳科学若手の会合宿
    • Place of Presentation
      相模原
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 精神・神経疾患の意思決定障害をターゲットにした薬物治療に向けて

    • Author(s)
      高橋 英彦
    • Organizer
      第87回日本薬理学会
    • Place of Presentation
      仙台
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 情動的意思決定の脳イメージング

    • Author(s)
      高橋 英彦
    • Organizer
      ヒューマンストレス産業技術研究会
    • Place of Presentation
      池田
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 先端研究を医療現場へ

    • Author(s)
      高橋 英彦
    • Organizer
      第26回総合病院精神医学会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Positive情動の認知神経科学

    • Author(s)
      高橋 英彦
    • Organizer
      第二回ポジティブサイコロジー医学会
    • Place of Presentation
      猪苗代
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Interdisciplinary neuroscientific studies on decision making between Japan and US.

    • Author(s)
      Hidehiko Takahashi
    • Organizer
      日本神経科学会
    • Place of Presentation
      Kyoto
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] なぜ他人の不幸は蜜の味なのか2014

    • Author(s)
      高橋英彦
    • Total Pages
      174
    • Publisher
      幻冬舎ルネッサンス
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2011-08-01   Modified: 2022-02-07  

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