| Co-Investigator(Kenkyū-buntansha) |
筒井 千尋 (小林 千尋) 東京都市大学, 工学部, 講師 (00570699)
岩下 光利 杏林大学, 医学部, 教授 (30124936)
金井 孝夫 東京女子医科大学, 医学部, その他 (60104642)
森 晃 東京都市大学, 工学部, 教授 (60219996)
工藤 美樹 広島大学, その他の研究科, 教授 (80241082)
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| Budget Amount *help |
¥99,710,000 (Direct Cost: ¥76,700,000、Indirect Cost: ¥23,010,000)
Fiscal Year 2016: ¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2015: ¥14,820,000 (Direct Cost: ¥11,400,000、Indirect Cost: ¥3,420,000)
Fiscal Year 2014: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2013: ¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2012: ¥32,370,000 (Direct Cost: ¥24,900,000、Indirect Cost: ¥7,470,000)
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| Outline of Final Research Achievements |
The use of inhaled plasma, generated by an atmospheric-pressure plasma (APP) reactor, in a rat myocardial infarction (MI) model resulted in increased saturation pulse oxygen (SpO2) in the blood, which suggests that this method can be beneficial in restoring heart function following cardiac ischemia. Additionally, in vivo blood pressure decreased from 89/81 to 73/60 mmHg in the abdominal aorta during plasma inhalation. Nitric oxide (NO) concentrations in the abdominal aorta increased after 20 s of plasma inhalation, reaching a maximum value at about 160 s and gradually decreased thereafter.
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