| Budget Amount *help |
¥178,230,000 (Direct Cost: ¥137,100,000、Indirect Cost: ¥41,130,000)
Fiscal Year 2016: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
Fiscal Year 2015: ¥34,060,000 (Direct Cost: ¥26,200,000、Indirect Cost: ¥7,860,000)
Fiscal Year 2014: ¥34,190,000 (Direct Cost: ¥26,300,000、Indirect Cost: ¥7,890,000)
Fiscal Year 2013: ¥33,930,000 (Direct Cost: ¥26,100,000、Indirect Cost: ¥7,830,000)
Fiscal Year 2012: ¥41,990,000 (Direct Cost: ¥32,300,000、Indirect Cost: ¥9,690,000)
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| Outline of Final Research Achievements |
In order to reveal the dynamic properties of the information transduction at the transcription cycle, new computational and informatics approaches have been developed. For the transcription factors in the enhanceosome and the relation to nucleosome, dynamic structural changes and the stabilities of the supramolecular complexes were analyzed so as to analyze the actual mechanisms in the transcription cycle. In addition, to extract biologically important and meaningful information and knowledges from the large scale data produced by the members of the research groups of the Transcription Cycle, mechanisms of transcription regulation were investigated based on the experimental data of Micro-array, RNA-seq, and ChIP-seq.
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