| Co-Investigator(Kenkyū-buntansha) |
山口 拓実 北陸先端科学技術大学院大学, マテリアルサイエンス研究科, 准教授 (60522430)
佐藤 匡史 名古屋市立大学, 大学院薬学研究科, 准教授 (80532100)
栗原 顕輔 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 特任准教授 (80740919)
矢木 真穂 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 助教 (40608999)
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| Budget Amount *help |
¥193,440,000 (Direct Cost: ¥148,800,000、Indirect Cost: ¥44,640,000)
Fiscal Year 2017: ¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2016: ¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2015: ¥31,070,000 (Direct Cost: ¥23,900,000、Indirect Cost: ¥7,170,000)
Fiscal Year 2014: ¥50,960,000 (Direct Cost: ¥39,200,000、Indirect Cost: ¥11,760,000)
Fiscal Year 2013: ¥61,230,000 (Direct Cost: ¥47,100,000、Indirect Cost: ¥14,130,000)
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| Outline of Final Research Achievements |
Biomolecules with complicated, flexible structures are self-organized through weak interactions giving rise to supermolecular complexes that adopt their own dynamic, asymmetric architectures. These processes are coupled with expression of integrated functions in the biomolecular systems. Toward an integrative understanding of the principles behind the biomolecular ordering processes, we integrated multidisciplinary approaches based on detailed analyses of dynamic structures and interactions of biomolecules at atomic level, in conjunction with the methodologies of molecular and cellular biology along with synthetic and computational techniques.
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