| Budget Amount *help |
¥107,640,000 (Direct Cost: ¥82,800,000、Indirect Cost: ¥24,840,000)
Fiscal Year 2017: ¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2016: ¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2015: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2014: ¥29,770,000 (Direct Cost: ¥22,900,000、Indirect Cost: ¥6,870,000)
Fiscal Year 2013: ¥23,530,000 (Direct Cost: ¥18,100,000、Indirect Cost: ¥5,430,000)
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| Outline of Final Research Achievements |
The purpose of this study is to create the molecular assembly (artificial cell) having the essential functions of cellular life (heredity using information molecules, metabolism, self-reproduction of container) and the self-propelling ability. We will reveal the physical background of the cellular life through the artificial cells. 1) We have succeeded to create two types of artificial cells. Both of them demonstrate the vesicle reproduction coupled with the information molecules. One of them shows a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), i.e., repeatable cell division. Both artificial cell has a potential of heredity and evolvability through the information molecules. 2)We also succeeded to create self-propelled tubular vesicles triggered by chemical stimuli, where the migration is coupled with the wavy motion of the tube. These findings shed light on the way from the molecular assembly to the cellular life.
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