Common priciple underlying memory dynamism based on rodents reconsolidation

• Project Area: Principles of memory dynamism elucidated from a diversity of learning systems
• Project/Area Number: 25115002
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: University of Toyama
• Principal Investigator: Inokuchi Kaoru 富山大学, 大学院医学薬学研究部(医学), 教授 (20318827)
• Co-Investigator(Renkei-kenkyūsha): OHKAWA Noriaki 富山大学, 大学院医学薬学研究部(医学), 講師 (80416651) ; SUZUKI Akinobu 富山大学, 大学院医学薬学研究部(医学), 助教 (40424684) ; NOMOTO Masanori 富山大学, 大学院医学薬学研究部(医学), 助教 (20636253)
• Project Period (FY): 2013-06-28 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥85,670,000 (Direct Cost: ¥65,900,000、Indirect Cost: ¥19,770,000); Fiscal Year 2017: ¥20,540,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥4,740,000); Fiscal Year 2016: ¥20,540,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥4,740,000); Fiscal Year 2015: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000); Fiscal Year 2014: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000); Fiscal Year 2013: ¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
• Keywords: 記憶 / 再固定化 / エングラム / 逆行性健忘 / オートファジー / 海馬 / 神経新生 / 長期増強 / 神経科学 / 脳・神経 / 記憶エングラム / 再固定 / 脳 / 脳･神経 / シナプス可塑性

Outline of Final Research Achievements

Autophagy, a protein degradation system, induces a memory destabilization upon retrieval. Complete retrograde amnesia is accompanied by erasure of memory trace.
Adult neurogenesis plays an important role in the maintenance of hippocampal memory capacity through recovery of saturated neuronal circuits.
Overlapping memory trace is indispensable for linking, but not recall, of individual memories.

Research Products

• [Journal Article] Autophagy Enhances Memory Erasure through Synaptic Destabilization (2018)
  • Author(s): Shehata Mohammad、Abdou Kareem、Choko Kiriko、Matsuo Mina、Nishizono Hirofumi、Inokuchi Kaoru
  • Journal Title: The Journal of Neuroscience Volume: 38 Issue: 15 Pages: 3809-3822
  • DOI: 10.1523/jneurosci.3505-17.2018
  • Peer Reviewed / Open Access
• [Journal Article] Adult Neurogenesis Conserves Hippocampal Learning Capacity (2018)
  • Author(s): Alam Jahangir、Kitamura Takashi、Saitoh Yoshito、Ohkawa Noriaki、Kondo Takashi、Inokuchi Kaoru
  • Journal Title: J Neurosci. Volume: -
  • DOI: 10.1101/200253
  • Peer Reviewed / Open Access
• [Journal Article] Behavioral, cellular, and synaptic tagging frameworks (2018)
  • Author(s): Nomoto Masanori、Inokuchi Kaoru
  • Journal Title: Neurobiology of Learning and Memory Volume: 18 Pages: 30065-0
  • DOI: 10.1016/j.nlm.2018.03.010
  • Peer Reviewed / Open Access
• [Journal Article] Synapse-specific representation of the identity of overlapping memory engrams. (2018)
  • Author(s): Kareem Abdou, Mohammad Shehata, Kiriko Choko, Hirofumi Nishizono, Mina Matsuo, Shin-ichi Muramatsu, Kaoru Inokuchi
  • Journal Title: Science Volume: -
  • Peer Reviewed / Open Access
• [Journal Article] 記憶想起 (2017)
  • Author(s): 鈴木章円，横瀬淳，井ノ口馨．
  • Journal Title: 脳科学辞典 Volume: -
  • DOI: 10.14931/bsd.7426
  • Open Access
• [Journal Article] 記憶固定化 (2017)
  • Author(s): 大川宜昭, 野本真順, 井ノ口馨
  • Journal Title: 脳科学辞典 Volume: -
  • DOI: 10.14931/bsd.7435
• [Journal Article] Overlapping memory trace indispensable for linking, but not recalling, individual memories. (2017)
  • Author(s): Yokose, J., Okubo-Suzuki, R., Nomoto, M., Ohkawa, N., Nishizono, H., Suzuki, A., Matsuo, M., Tsujimura, S., Takahashi, Y., Nagase, M.,Watabe, A.M., Sasahara, M., Kato, F., Inokuchi, K.
  • Journal Title: Science Volume: 355 Issue: 6323 Pages: 398-403
  • DOI: 10.1126/science.aal2690
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Cellular tagging as a neural network mechanism for behavioral tagging. (2016)
  • Author(s): Nomoto, M., Ohkawa, N., Nishizono, H., Yokose, J., Suzuki, A., Matuo, M., Tsujimura, S., Takahashi, Y., Nagase, M., Watabe, A.M., Kato, F., Inokuchi, K.
  • Journal Title: Nature Communications Volume: 7:12319 Issue: 1 Pages: 1-11
  • DOI: 10.1038/ncomms12319
  • Peer Reviewed / Open Access
• [Journal Article] Frequency-specific stimulations induce reconsolidation of long-term potentiation in freely moving rats (2016)
  • Author(s): Okubo-Suzuki R., Saitoh Y., Shehata M., Zhao Q., Enomoto H., and Inokuchi K.
  • Journal Title: Molecular Brain Volume: 9 Issue: 1
  • DOI: 10.1186/s13041-016-0216-4
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Artificial association of pre-stored information to generate a qualitatively new memory (2015)
  • Author(s): Ohkawa N, Saitoh Y, Suzuki A, Tsujimura S, Murayama E, Kosugi S, Nishizono H, Matsuo M, Takahashi Y, Nagase M, Sugimura YK, Watabe AM, Kato F, Inokuchi K
  • Journal Title: Cell Reports Volume: 11 Issue: 2 Pages: 1-9
  • DOI: 10.1016/j.celrep.2015.03.017
  • Peer Reviewed / Open Access
• [Journal Article] Targeting of ribosomal protein S6 to dendritic spines by in vivo high frequency stimulation to induce long-term potentiation in the dentate gyrus (2015)
  • Author(s): Nihonmatsu I., Ohkawa N., Saitoh Y. and Inokuchi K.
  • Journal Title: Biology Open Volume: 4 Issue: 11 Pages: 1387-1394
  • DOI: 10.1242/bio.013243
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A lognormal recurrent network model for burst generation during hippocampal sharp waves (2015)
  • Author(s): Omura Y., Carvalho M., Inokuchi K. and Fukai T.
  • Journal Title: J. Neurosci. Volume: 35 Issue: 43 Pages: 14585-14601
  • DOI: 10.1523/jneurosci.4944-14.2015
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Cofilin1 Controls Transcolumnar Plasticity in Dendritic Spines in Adult Barrel Cortex (2015)
  • Author(s): Tadashi Tsubota, Reiko Okubo-Suzuki, Yohei Ohashi, Keita Tamura, Koshin Ogata, Masae Yaguchi, Makoto Matsuyama, Kaoru Inokuchi, Yasushi Miyashita
  • Journal Title: PLOS Biology Volume: 13(2) Issue: 2 Pages: e1002070-e1002070
  • DOI: 10.1371/journal.pbio.1002070
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Artificial Association of Pre-stored Information to Generate a Qualitatively New Memory. (2015)
  • Author(s): Ohkawa N., Saitoh Y., Suzuki A., Tsujimura S., Murayama E., Kosugi S., Nishizono H., Matsuo M., Takahashi Y., Nagase M., Sugimura Y.K., Watabe A.M., Kato F., and Inokuchi K.
  • Journal Title: Cell Reports Volume: 11 Pages: 261-269
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] メモリーアロケーションのメカニズム (2014)
  • Author(s): 佐野良威，井ノ口馨
  • Journal Title: 生体の科学 Volume: 65 Pages: 482-483
• [Journal Article] Does autophagy work in synaptic plasticity and memory? (2014)
  • Author(s): Shehata M. and Inokuchi K.
  • Journal Title: Reviews in the Neurosciences Volume: -
  • Peer Reviewed
• [Journal Article] Role of the Adult Neurogenesis in Hippocampal-Cortical Memory Consolidation. (2014)
  • Author(s): Kitamura T. and Inokuchi K.
  • Journal Title: Molecular Brain Volume: VOL7 Issue: 1 Pages: 13-13
  • DOI: 10.1186/1756-6606-7-13
  • Peer Reviewed
• [Journal Article] 恐怖記憶研究鳥瞰－最近の知見と展望－ (2013)
  • Author(s): 井ノ口馨
  • Journal Title: 不安障害研究 Volume: 5巻 Pages: 13-21
  • NAID: 130005003890
  • Peer Reviewed
• [Presentation] Overlapping memory trace is indispensable for linking, but not recalling, individual memories. (2017)
  • Author(s): Inokuchi K.
  • Organizer: The 2017 Cold Spring Harbor Asia Symposium, Francis Crick Symposium - Transforming Neurosciences: Questions & Experiments
  • Int'l Joint Research / Invited
• [Presentation] 記憶同士を関連付ける細胞集団． (2017)
  • Author(s): 横瀬 淳，井ノ口馨
  • Organizer: 第16回日本トラウマティック・ストレス学会
  • Invited
• [Presentation] Manipulating memories based on engram technology. (2017)
  • Author(s): Inokuchi K.
  • Organizer: 2017 International Brain Science Summit
  • Int'l Joint Research / Invited
• [Presentation] Dynamics of Memory Engram Cells. (2017)
  • Author(s): 井ノ口馨
  • Organizer: 第40回日本神経科学大会 シンポジウム
  • Invited
• [Presentation] Specific regulation of CS-US association in fear memory by manipulating the activity of parietal association cortex. (2017)
  • Author(s): Suzuki A., Kosugi-Ushijima S., Murayama E., Ohkawa N., Matsuo M., Nishizono H., and Inokuchi K.
  • Organizer: 第40回日本神経科学大会
• [Presentation] Irreversible erasure of memory engram. (2017)
  • Author(s): Abdou K.M., Shehata M., Zhao Q., Nishizono H., Matsuo M., Muramatsu S, and Inokuchi K.
  • Organizer: 第40回日本神経科学大会
• [Presentation] Identification of characteristic dynamism of engram cells during learning. (2017)
  • Author(s): Ghandour K., Ohkawa N., Fung C.C.A., Saitoh Y., Takekawa T., Asai H., Okubo-Suzuki R., Nomoto M., Tsujimura S., Nishizono H., Matsuo M., Tsujimura M., Ohkura M., Nakai J., Hayashi Y., Fukai T., and Inokuchi K.
  • Organizer: 第40回日本神経科学大会
• [Presentation] Ultra-thin fluorescence endoscope imaging system for functional brain imaging. (2017)
  • Author(s): Osanai M., Ohkawa N., Sakamoto K., Miwa H., Kikuta S., Tamura A., Sato A., Ohkura M., Kojima T., Kohmura Y., Nakai J., Hayashi Y., Yanagawa Y., Inokuchi K., Homma N., Mushiake H.
  • Organizer: 第40回日本神経科学大会
• [Presentation] Overlapping memory trace is indispensable for linking, but not recalling, individual memories. (2017)
  • Author(s): Inokuchi K.
  • Organizer: Molecular and Cellular Cognition Society - Asia 2017 Meeting
  • Int'l Joint Research / Invited
• [Presentation] Cell ensemble mechanisms underlying memory association. (2017)
  • Author(s): Inokuchi K.
  • Organizer: Pain and Cortex Summer Meeting
  • Int'l Joint Research / Invited
• [Presentation] エングラムから探る「記憶が関連づけされる仕組み」． (2017)
  • Author(s): 井ノ口馨
  • Organizer: 第29回高遠・分子細胞生物学シンポジウム
  • Invited
• [Presentation] Overlapping memory trace indispensable for linking, but not recalling, individual memories. (2017)
  • Author(s): Inokuchi K.
  • Organizer: The 20th Annual Meeting of the Korean Society for Brain and Neural Science "Challenge the Brain, Change the Future"
  • Int'l Joint Research / Invited
• [Presentation] Neuronal ensemble distinguishes overlapping memories by engram-specific synaptic plasticity. (2017)
  • Author(s): Inokuchi K.
  • Organizer: The 12th International Conference of Neurons and Brain Diseases, Association for the study of neurons and diseases
  • Int'l Joint Research
• [Presentation] Mechanisms underlying the association and the identity of memories. (2017)
  • Author(s): Inokuchi K.
  • Organizer: The 16th Annual MCCS meeting
  • Int'l Joint Research / Invited
• [Presentation] Complete erasure of memory trace from engram cells. (2017)
  • Author(s): Abdou K.M., Shehata M., Zhao Q., Nishizono H., Matsuo M., Muramatsu S, and Inokuchi K.
  • Organizer: The 16th Annual MCCS meeting
  • Int'l Joint Research
• [Presentation] Unraveling the dynamism of engram cells during contextual memory processing. (2017)
  • Author(s): Ghandour K., Ohkawa N., Fung C.C.A., Saitoh Y., Takekawa T., Asai H., Okubo-Suzuki R., Nomoto M., Soya S., Tsujimura S., Nishizono H., Matsuo M., Sato M., Ohkura M., Nakai J., Hayashi Y., Sakurai T., Osanai M., Fukai T., and Inokuchi K.
  • Organizer: The 16th Annual MCCS meeting
  • Int'l Joint Research
• [Presentation] Complete erasure of memory trace from engram cells. (2017)
  • Author(s): Abdou K.M., Shehata M., Zhao Q., Nishizono H., Matsuo M., Muramatsu S, and Inokuchi K.
  • Organizer: Neuroscience 2017, Annual Meeting of Society for Neuroscience
  • Int'l Joint Research
• [Presentation] Unraveling the dynamism of engram cells during contextual memory processing. (2017)
  • Author(s): Ghandour K., Ohkawa N., Fung C.C.A., Saitoh Y., Takekawa T., Asai H., Okubo-Suzuki R., Nomoto M., Soya S., Tsujimura S., Nishizono H., Matsuo M., Sato M., Ohkura M., Nakai J., Hayashi Y., Sakurai T., Osanai M., Fukai T., and Inokuchi K.
  • Organizer: Neuroscience 2017, Annual Meeting of Society for Neuroscience
  • Int'l Joint Research
• [Presentation] 記憶痕跡セル・アンサンブルによる記憶情報処理． (2017)
  • Author(s): 大川宜昭，井ノ口馨
  • Organizer: 第36回日本認知症学会学術集会・シンポジウム：記憶のメカニズムとシナプスイ メージング
  • Invited
• [Presentation] 記憶をつくりかえる． (2017)
  • Author(s): 井ノ口馨
  • Organizer: 第21回公益社団法人日本顎顔面インプラント学会総会・学術大会
  • Invited
• [Presentation] Cell assembly mechanisms underlying memory association. (2017)
  • Author(s): Inokuchi K.
  • Organizer: The 6th Annual IIIS Symposium
  • Int'l Joint Research / Invited
• [Presentation] Optical manipulation of parietal association cortex regulates contextual fear memory. (2016)
  • Author(s): Suzuki A., Kosugi-Ushijima S., Ohkawa N., Matsuo M., Nishizono H., and Inokuchi K.
  • Organizer: Neuroscience 2016, Annual Meeting of Society for Neuroscience
  • Place of Presentation: San Diego, USA
  • Year and Date: 2016-11-12
  • Int'l Joint Research
• [Presentation] Neuronal ensemble orchestrated intersection of two distinct emotional memory traces. (2016)
  • Author(s): Yokose J., Okubo-Suzuki R., Nomoto M., Ohkawa N., Nishizono H., Matsuo M., Suzuki A., Takahashi Y., Nagase M., Watabe A.M., Sasahara M., Kato F., and Inokuchi K.
  • Organizer: Neuroscience 2016, Annual Meeting of Society for Neuroscience
  • Place of Presentation: San Diego, USA
  • Year and Date: 2016-11-12
  • Int'l Joint Research
• [Presentation] Adult neurogenesis in maintenance of the hippocampal learning capacity. (2016)
  • Author(s): Alam M., Kitamura T., Saitoh Y., Ohkawa N., Kondo T., and Inokuchi K.
  • Organizer: Neuroscience 2016, Annual Meeting of Society for Neuroscience
  • Place of Presentation: San Diego, USA
  • Year and Date: 2016-11-12
  • Int'l Joint Research
• [Presentation] Autophagy induction enhances memory destabilization beyond reconsolidation boundary. (2016)
  • Author(s): Shehata M.H., Zhao Q., Abdou K., Matsuo M., Nishizono H., and Inokuchi K.
  • Organizer: Neuroscience 2016, Annual Meeting of Society for Neuroscience
  • Place of Presentation: San Diego, USA
  • Year and Date: 2016-11-12
  • Int'l Joint Research
• [Presentation] Neural ensemble mechanisms underlying the interaction between distinct memories. (2016)
  • Author(s): Inokuchi K.
  • Organizer: The 19th Korean Society for Brain and Neural Science
  • Place of Presentation: Gyeonggi-do, Korea
  • Year and Date: 2016-09-28
  • Int'l Joint Research / Invited
• [Presentation] Autophagy induction enhances memory destabilization beyond reconsolidation boundary. (2016)
  • Author(s): Inokuchi K.
  • Organizer: The 11th International Conference of Neurons and Brain Diseases
  • Place of Presentation: Vancouver, Canada
  • Year and Date: 2016-07-14
  • Int'l Joint Research
• [Presentation] Generating an artificial CS-US associative memory by manipulation of parietal association cortex (2015)
  • Author(s): Suzuki A., Kosugi-Ushijima S., Ohkawa N., Matsuo M., Nishizono H., and Inokuchi K.
  • Organizer: Neuroscience 2015, Annual Meeting of Society for Neuroscience
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-17
  • Int'l Joint Research
• [Presentation] Enhancing memory destabilization through protein degradation induction (2015)
  • Author(s): Shehata M., Zhao Q., Abdou K., Okubo-Suzuki R., Saitoh Y., Kitamura T., Nishizono H., Matsuo M., Ohkawa N., and Inokuchi K.
  • Organizer: Neuroscience 2015, Annual Meeting of Society for Neuroscience
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-17
  • Int'l Joint Research
• [Presentation] Overlapping in two cellular ensembles in the hippocampal CA1 region is important for behavioral tagging (2015)
  • Author(s): Nomoto M., Ohkawa N., Nishizono H., Matsuo M., Yokose J., Takahashi Y., Nagase M., Suzuki A., Watabe A.M., Kato F., and Inokuchi K.
  • Organizer: Neuroscience 2015, Annual Meeting of Society for Neuroscience
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-17
  • Int'l Joint Research
• [Presentation] Synergistic activity during retrieval of neuronal ensembles between two distinct memory traces generates cross-modal linkage (2015)
  • Author(s): Yokose J., Nomoto M., Okubo-Suzuki R., Ohkawa N., Nishizono H., Matsuo M., Suzuki A., Takahashi Y., Nagase M., Watabe A.M., Kato F., and Inokuchi K.
  • Organizer: Neuroscience 2015, Annual Meeting of Society for Neuroscience
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-17
  • Int'l Joint Research
• [Presentation] Adult neurogenesis modulates the hippocampal learning capacity (2015)
  • Author(s): Alam M., Kitamura T., Saitoh Y., Ohkawa N., Kondo T., and Inokuchi K.
  • Organizer: Neuroscience 2015, Annual Meeting of Society for Neuroscience
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-17
  • Int'l Joint Research
• [Presentation] Generating an artificial CS-US associative memory by manipulation of parietal association cortex (2015)
  • Author(s): Suzuki A., Kosugi-Ushijima S., Ohkawa N., Matsuo M., Nishizono H., and Inokuchi K.
  • Organizer: 14th Annual MCCS meeting in Chicago
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-15
  • Int'l Joint Research
• [Presentation] Enhancing memory destabilization through protein degradation induction (2015)
  • Author(s): Shehata M., Zhao Q., Abdou K., Okubo-Suzuki R., Saitoh Y., Kitamura T., Nishizono H., Matsuo M., Ohkawa N., and Inokuchi K.
  • Organizer: 14th Annual MCCS meeting in Chicago
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-15
  • Int'l Joint Research
• [Presentation] Overlapping in two cellular ensembles in the hippocampal CA1 region is important for behavioral tagging (2015)
  • Author(s): Nomoto M., Ohkawa N., Nishizono H., Matsuo M., Yokose J., Takahashi Y., Nagase M., Suzuki A., Watabe A.M., Kato F., and Inokuchi K.
  • Organizer: 14th Annual MCCS meeting in Chicago
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-15
  • Int'l Joint Research
• [Presentation] Synergistic activity during retrieval of neuronal ensembles between two distinct memory traces generates cross-modal linkage (2015)
  • Author(s): Yokose J., Nomoto M., Okubo-Suzuki R., Ohkawa N., Nishizono H., Matsuo M., Suzuki A., Takahashi Y., Nagase M., Watabe A.M., Kato F., and Inokuchi K.
  • Organizer: 14th Annual MCCS meeting in Chicago
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-15
  • Int'l Joint Research
• [Presentation] Adult neurogenesis modulates the hippocampal learning capacity (2015)
  • Author(s): Alam M., Kitamura T., Saitoh Y., Ohkawa N., Kondo T., and Inokuchi K.
  • Organizer: 14th Annual MCCS meeting in Chicago
  • Place of Presentation: シカゴ（アメリカ合衆国）
  • Year and Date: 2015-10-15
  • Int'l Joint Research
• [Presentation] Cellular Ensemble Mechanisms Underlying the Interaction of Distindt Units of Information (2015)
  • Author(s): 井ノ口馨
  • Organizer: 東北大学知のフォーラム 脳科学最前線 「Memory and Mind」
  • Place of Presentation: 東北大学知の館（仙台市青葉区）
  • Year and Date: 2015-09-28
  • Int'l Joint Research / Invited
• [Presentation] 虚記憶を創り出す：細胞集成体理論を基として (2015)
  • Author(s): 井ノ口馨
  • Organizer: 第39回日本神経心理学会学術集会
  • Place of Presentation: 札幌市教育文化会館（札幌市中央区）
  • Year and Date: 2015-09-10
  • Invited
• [Presentation] Artificial association of pre-stored information in hippocampus and amygdala (2015)
  • Author(s): Ohkawa N., Saitoh Y., Suzuki A., Tsujimura S., Murayama E., Kosugi S., Nishizono H., Matsuo M., Takahashi Y., Nagase M., Sugimura Y.K., Watabe A.M., Kato F., Inokuchi K.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] Parietal association cortex regulates CS-US association of contextual fear memory (2015)
  • Author(s): Suzuki A., Kosugi S., Ohkawa N., Nishizono H., Inokuchi K.：
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] Enhancing memory destabilization through protein degradation induction (2015)
  • Author(s): Shehata M., Nishizono H., Inokuchi K.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] Overlapping in two cellular ensembles in the hippocampal CA1 region is required for behavioral tagging (2015)
  • Author(s): Nomoto M., Yokose J., Takahashi Y., Nagase M., Suzuki A., Ohkawa N., Nishizono H., Watabe A.M., Kato F., Inokuchi K.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] Synergistic activity between distinct neuronal ensembles creates the association of memory (2015)
  • Author(s): Yokose J., Nomoto M., Okubo-Suzuki R., Takahashi Y., Nagase M., Suzuki A., Ohkawa N., Nishizono H., Watabe A.M., Kato F., Inokuchi K.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] LTP reconsolidation revealed by field EPSP recording in freely moving rats (2015)
  • Author(s): Zhao Q., Yamamoto A., Okubo-Suzuki R., Saitoh Y., Inokuchi K.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] Adult neurogenesis modulates the hippocampal learning capacity (2015)
  • Author(s): Jahangir A.M., Kitamura T., Saitoh Y., Ohkawa N., Kondo T., Inokuchi K.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] Automatic detection system of cell shape and spike timing for calcium imaging data using iterative sequential quadratic programing (2015)
  • Author(s): Takekawa T., Sato M., Ohkawa N., Inokuchi K., Hayashi Y., Fukai T.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸国際会議場、神戸国際展示場（神戸市中央区）
  • Year and Date: 2015-07-28
• [Presentation] Cell ensemble mechanisms underlying the association of two independent memories (2015)
  • Author(s): Inokuchi K.
  • Organizer: The 10th International Conference of Neurons and Brain Diseases
  • Place of Presentation: Xian（中国）
  • Year and Date: 2015-06-22
  • Int'l Joint Research
• [Presentation] Artificial association of information residing in hippocampus and amygdala (2014)
  • Author(s): Ohkawa N., Saitoh Y., Suzuki A., Tsujimura S., Murayama E., Nishizono H., Matsuo M., Takahashi Y., Nagase M., Sugimura Y.K., Watabe A.M., Kato F., and Inokuchi K.
  • Organizer: Neuroscience 2014, Annual Meeting of Society for Neuroscience
  • Place of Presentation: Washington D.C. （アメリカ合衆国）
  • Year and Date: 2014-11-15 – 2014-11-19
• [Presentation] Artificial association of information residing in hippocampus and amygdala (2014)
  • Author(s): Ohkawa N., Saitoh Y., Suzuki A., Tsujimura S., Murayama E., Nishizono H., Matsuo M., Takahashi Y., Nagase M., Sugimura Y.K., Watabe A.M., Kato F., and Inokuchi K.
  • Organizer: 13th Annual MCCS
  • Place of Presentation: Washington D.C. （アメリカ合衆国）
  • Year and Date: 2014-11-14
• [Presentation] 神経細胞集団の動態による記憶統合プロセス (2014)
  • Author(s): 井ノ口馨
  • Organizer: 第37回日本神経科学大会大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-09-11 – 2014-09-13
• [Presentation] 異なるセルアンサンブルの光遺伝学的活性化による連合記憶の人工的創出 (2014)
  • Author(s): 大川宜昭，斎藤喜人，鈴木章円，辻村周平，村山絵美，西園啓文，松尾美奈，高橋由香里，長瀬将志，杉村弥恵，渡部文子，加藤総夫，井ノ口馨
  • Organizer: 第37回日本神経科学大会大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-09-11 – 2014-09-13
• [Presentation] 繰返し想起による異なる二つの記憶痕跡の相互作用 (2014)
  • Author(s): 横瀬淳，野本真順，鈴木（大久保）玲子，鈴木章円，井ノ口馨
  • Organizer: 第37回日本神経科学大会大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-09-11 – 2014-09-13
• [Presentation] 行動タグの成立時には海馬の歯状回、CA3ではなくCA1において細胞の重複した活動が増える (2014)
  • Author(s): 野本 真順，横瀬 淳，大澤 香織，鈴木 章円，井ノ口 馨
  • Organizer: 第37回日本神経科学大会大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-09-11 – 2014-09-13
• [Presentation] Adult neurogenesis and the hippocampal learning capacity (2014)
  • Author(s): Jahangir A.M., Kitamura T., Ohkawa N., Kondo T., Inokuchi K.
  • Organizer: 第37回日本神経科学大会大会
  • Place of Presentation: パシフィコ横浜（神奈川県横浜市）
  • Year and Date: 2014-09-11 – 2014-09-13
• [Presentation] Artificial Association of Pre-Stored Information. The 9th International Conference of Neurons and Brain Diseases (2014)
  • Author(s): Inokuchi K.
  • Organizer: International Frontier Symposium for Neuroscience
  • Place of Presentation: Madrid（スペイン）
  • Year and Date: 2014-07-16
• [Presentation] 恐怖記憶と脳 (2014)
  • Author(s): 井ノ口馨
  • Organizer: 第６回日本不安障害学会学術大会
  • Place of Presentation: 東京大学山上会館伊藤謝恩ホール（東京都文京区）
  • Invited
• [Presentation] Artificial activation of distinct cell ensembles facilitates an association between two memories. (2014)
  • Author(s): Inokuchi K.
  • Organizer: International Symposium on Glyco-Neuroscience
  • Place of Presentation: 淡路夢舞台国際会議場（兵庫県淡路市）
  • Invited
• [Presentation] 異なるセルアセンブリの人為的活性化による人工連合記憶の創出. (2013)
  • Author(s): 大川宜昭，斎藤喜人，鈴木章円，辻村周平，村山絵美，西園啓史，松尾美奈，高橋由香里，永瀬将志，杉村弥恵，渡部文子，加藤総夫，井ノ口馨
  • Organizer: 第36回日本分子生物学会年会
  • Place of Presentation: 神戸コンベンションセンター（神戸市中央区港島中町）
• [Presentation] 神経ネットワークから眺めたPTSDの病態 (2013)
  • Author(s): 井ノ口馨
  • Organizer: 第23回日本臨床精神神経薬理学会、第43回日本神経精神薬理学会 合同年会
  • Place of Presentation: 沖縄コンベンションセンター（沖縄県宜野湾市）
  • Invited
• [Presentation] 記憶制御の理解に向けて－分子から回路・行動へ－ (2013)
  • Author(s): 井ノ口馨
  • Organizer: 第22回海馬と高次機能学会
  • Place of Presentation: 金沢湯涌創作の森（石川県金沢市）
  • Invited
• [Presentation] 独立した情報を関連付けるニューロンモデル (2013)
  • Author(s): 大村佳之，深井朋樹，井ノ口馨
  • Organizer: 第22回海馬と高次機能学会
  • Place of Presentation: 金沢湯涌創作の森（石川県金沢市）
• [Presentation] Synaptic reconsolidation. (2013)
  • Author(s): Inokuchi K
  • Organizer: The 8th International Conference of Neurons and Brain Diseases in Singapore
  • Place of Presentation: National University of Singapore (Singapore)
  • Invited
• [Presentation] Optical stimulation of distinct cell assemblies generates a new artificial associative-memory．
  • Author(s): Inokuchi K.
  • Organizer: International Frontier Symposium for Neuroscience
  • Place of Presentation: 西安交通大学前沿科学研究院（中国・せん西省西安市）
  • Invited
• [Presentation] Artificial activation of distinct cell assemblies makes new associative memory.
  • Author(s): Inokuchi K., Saitoh Y., Suzuki A.,Tsujimura S., Murayama E., Nishizono H., Matsuo M., Takahashi Y., Nagase M., Sugimura Y.K., Watabe A.M., Kato F., and Ohkawa N.:
  • Organizer: 12th Annual MCCS meeting in San Diego
  • Place of Presentation: カリフォルニア工科大学（米国カリフォルニア州Pasadena）
  • Invited
• [Presentation] 恐怖記憶形成のメカニズムとPTSD予防
  • Author(s): 井ノ口馨
  • Organizer: 第184回北陸精神神経学会
  • Place of Presentation: 富山大学杉谷キャンパス（富山県富山市）
  • Invited
• [Book] 実験医学，個々の記憶どうしをつなぐ神経細胞集団のメカニズム. (2017)
  • Author(s): 横瀬 淳，井ノ口馨
  • Total Pages: 4
  • Publisher: 羊土社
• [Book] 日経サイエンス 11月号，記憶をつくり変える. (2017)
  • Author(s): 井ノ口馨
  • Total Pages: 10
  • Publisher: 日経サイエンス
• [Book] Ｑ＆Ａ－神経科学の素朴な疑問 Ｑ ど忘れはどうして起こるのですか？. 月刊 臨床神経科学 ブレインマシンインターフェース 34 (2016)
  • Author(s): 鈴木章円，井ノ口馨
  • Total Pages: 130
  • Publisher: 中外医学社
• [Book] 虚記憶を創り出す：細胞集成体理論を基として. 神経心理学 3 (2016)
  • Author(s): 井ノ口馨
  • Total Pages: 102
  • Publisher: 日本神経心理学会
• [Book] 記憶痕跡とメモリーアロケーション. 生体の科学・特集 記憶ふたたび, (2016)
  • Author(s): 佐野良威，大川宜昭，鈴木章円，井ノ口 馨
  • Total Pages: 92
  • Publisher: 医学書院
• [Book] 記憶をあやつる (2015)
  • Author(s): 井ノ口馨
  • Total Pages: 198
  • Publisher: 角川書店
• [Book] 記憶のダイナミクスとそのメカニズム，リハビリテーションのためのニューロサイエンス 脳科学からみる機能回復 (2015)
  • Author(s): 大川 宜昭, 浦川 将
  • Total Pages: 296
  • Publisher: メジカルビュー社
• [Book] オプトジェネティクスによる記憶の操作. 実験医学 33 (2015)
  • Author(s): 大川宜昭，井ノ口馨
  • Total Pages: 153
  • Publisher: メジカルビュー社
• [Book] "Activity-dependent protein transport as a synaptic tag." Synaptic Tagging and Capture (2015)
  • Author(s): Okada, D. and Inokuchi, K.
  • Publisher: Springer, New York
• [Book] 記憶痕跡，脳科学辞典（オンライン辞典） (2014)
  • Author(s): 鈴木章円，大川 宜昭，野本 真順，井ノ口 馨
  • Publisher: 担当編集委員：河西 春郎（東京大学 大学院医学系研究科）
• [Book] 第56章 経験とシナプス結合の精緻化，カンデル神経科学 第5版 (翻訳） (2014)
  • Author(s): 井ノ口 馨，野本真順
  • Publisher: メディカル・サイエンス・インターナショナル
• [Book] 付録E ニューラルネットワーク，カンデル神経科学 第5版 (翻訳） (2014)
  • Author(s): 井ノ口 馨，横瀬 淳
  • Publisher: メディカル・サイエンス・インターナショナル
• [Book] 記憶をコントロールする－分子脳科学の挑戦－ (2014)
  • Author(s): 井ノ口馨
  • Publisher: 岩波書店
• [Remarks] 富山大学大学院医学薬学研究部生化学講座
  • URL: http://www.med.u-toyama.ac.jp/bmb/index-j.html
• [Remarks] 生化学講座
  • URL: http://www.med.u-toyama.ac.jp/bmb/index-j.html
• [Remarks] 富山大学大学院 医学薬学研究部（医学） 生化学講座
  • URL: http://www.med.u-toyama.ac.jp/bmb/index-j.html
• [Remarks] Nature
  • URL: http://www.nature.com/nature/journal/v520/n7546/full/520135a.html
• [Remarks] EurekAlert
  • URL: http://www.eurekalert.org/pub_releases/2015-04/cp-rca032615.php
• [Remarks] SciGuru Science News
  • URL: http://www.sciguru.org/newsitem/18834/researchers-create-artificial-link-between-unrelated-memories
• [Remarks] NHK Eテレ サイエンスZERO
  • URL: http://www.nhk.or.jp/zero/contents/dsp536.html
• [Remarks] 富山大学大学院医学薬学研究部（医学）生化学講座ホームページ
  • URL: http://www.med.u-toyama.ac.jp/bmb/index-j.html
• [Remarks] 富山大学大学院医学薬学研究部（医学）生化学講座ホームページ
  • URL: http://www.med.u-toyama.ac.jp/bmb/index-j.html