| Budget Amount *help |
¥76,180,000 (Direct Cost: ¥58,600,000、Indirect Cost: ¥17,580,000)
Fiscal Year 2017: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2016: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2015: ¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2014: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2013: ¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
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| Outline of Final Research Achievements |
In this study, we investigated molecular, cellular and circuit mechanisms underlying spatial and temporal dynamism of olfactory memory by using zebrafish as a model organism. First, we identified the four olfactory centers in the zebrafish forebrain (ventral telencephalon, posterior telencephalon, right habenula, posterit tuberculum) where odor information is conveyed from the mitral cells in the olfactory bulb. Next, we analyzed neural mechanism for appetitive olfactory conditioning in which fish are memorized with a given odorant stimulus associated with food reward. Finally, we dissected two distinct olfactory neural circuits that mediate attractive responses to food odors (amino acids and nucleotides) or sex pheromone (prostaglandin F2a). These findings will shed light on elucidation of commonality and difference between the innate and learned behaviors of animals.
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