| Budget Amount *help |
¥64,740,000 (Direct Cost: ¥49,800,000、Indirect Cost: ¥14,940,000)
Fiscal Year 2017: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Fiscal Year 2016: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Fiscal Year 2015: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Fiscal Year 2014: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Fiscal Year 2013: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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| Outline of Final Research Achievements |
To clarify the underlying mechanisms of neuron-microglia abnormalities in schizophrenia and other neuropsychiatric disorders, we have newly developed two translational research tools (cells), (1) directly induced microglia-like (iMG) cells from human blood monocytes for two weeks, and (2) directly induced early-phase induced neuronal (iN) cells from human fibroblasts for two weeks. Using these cells, we have revealed disease-specific cellular level abnormalities in some neuropsychiatric disorders.
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