Co-Investigator(Kenkyū-buntansha) |
松下 拓也 九州大学, 大学病院, 講師 (00533001)
山崎 亮 九州大学, 医学研究院, 准教授 (10467946)
松瀬 大 九州大学, 医学研究院, 助教 (70596395)
真崎 勝久 九州大学, 医学研究院, 助教 (90612903)
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Budget Amount *help |
¥60,970,000 (Direct Cost: ¥46,900,000、Indirect Cost: ¥14,070,000)
Fiscal Year 2017: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2016: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2015: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2014: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2013: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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Outline of Final Research Achievements |
In the central nervous system, the same number of glial cells as nerve cells exist. These consist of astroglia, oligodendroglia and microglia, each of which is highly differentiated and is responsible for the central nervous system homeostasis. In recent years, glial cell dysfunction as a cause of neurological diseases and psychiatric disorders attracts attention. Glial cells are directly connected to each other by gap junctions composed of connexin proteins to form a huge network. We examined the mechanism of neuropathy-induced connexin abnormalities in autopsy specimens and model animals of patients with neurological disorders.
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