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Understanding the neural basis of empathetic behaviors

Planned Research

Project AreaEmpathic system
Project/Area Number 25118009
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Complex systems
Research InstitutionNara Institute of Science and Technology

Principal Investigator

Komai Shoji  奈良先端科学技術大学院大学, 先端科学技術研究科, 准教授 (50420469)

Co-Investigator(Kenkyū-buntansha) 池田 和司  奈良先端科学技術大学院大学, 先端科学技術研究科, 教授 (10262552)
Project Period (FY) 2013-06-28 – 2018-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥103,480,000 (Direct Cost: ¥79,600,000、Indirect Cost: ¥23,880,000)
Fiscal Year 2017: ¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2016: ¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2015: ¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2014: ¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2013: ¥24,960,000 (Direct Cost: ¥19,200,000、Indirect Cost: ¥5,760,000)
Keywords行動解析 / コンピュータビジョン / 共感性 / 社会行動 / 神経回路解析 / 行動 / 回路
Outline of Final Research Achievements

Understanding our behavior representing to the neural activities of network is quite important to recognize its precise meanings and predict it. In many neuro-developmental disorders in human, such as autism spectrum disorder (ASD), social interaction is disrupted. Disadvantages of that are some of the important features behind the background, which are not apparently visible (conspicuous but subtle), may be overlooked, or are not analyzed due to the complexity of inter-connected behavioral features during human performance. The model mice were video-recorded singly in an open field. Then, behavioral motion features were extracted and analyzed by using this system. The results clearly distinguished the subtle changes of mice and even identified behavioral difference in ASD model mice from the control subjects. Thus, it lays the pavement for the potential of generalized use of this method both for animal model and for human subject in future.

Academic Significance and Societal Importance of the Research Achievements

共感性などの社会行動は擬人的観測によって行われてきたが,テクノロジーの進展により神経活動の詳細な解析・介入が可能となった現在,定量的行動解析が極めて重要な課題となってきている.微小神経回路の表出をヒトが目で観測し同定することは極めて困難であるからである.一方で,一連の行動の中に含まれる文法的構成,行動の小さなチャンクの遷移についての理解も全く進められていない.自動走行の車載カメラをはじめ画像解析による物体認識の精度が格段に向上した今,これらの技術を用いて行動の客観的,定量的理解を行うことが可能となってきているとともに,これらのことを先んじて行うことは社会的にも極めて意義深いことであると言える.

Report

(6 results)
  • 2018 Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (32 results)

All 2019 2018 2017 2016 2015 2014 2013 Other

All Int'l Joint Research (1 results) Journal Article (13 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 12 results,  Open Access: 6 results) Presentation (16 results) (of which Int'l Joint Research: 10 results,  Invited: 1 results) Book (2 results)

  • [Int'l Joint Research] KMITL(タイ)

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Auditory-induced response in the primary sensory cortex of rodents2018

    • Author(s)
      Maruyama Atsuko T.、Komai Shoji
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 12 Pages: e0209266-e0209266

    • DOI

      10.1371/journal.pone.0209266

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Biodiversity, drug discovery, and the future of global health: Introducing the biodiversity to biomedicine consortium, a call to action.2017

    • Author(s)
      Neergheen-Bhujun V, Awan AT, Baran Y, Bunnefeld N, Chan K, Dela Cruz TE, Egamberdieva D, Elsasser S, Johnson MV, Komai S, Konevega AL, Malone JH, Mason P, Nguon R, Piper R, Shrestha UB, Pesic M, Kagansky A.
    • Journal Title

      J Glob Health

      Volume: 7(2) Issue: 2 Pages: 020304-020304

    • DOI

      10.7189/jogh.07.020304

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Building Bridges through Science.2017

    • Author(s)
      Lissek T, Adams M, Komai S et al.
    • Journal Title

      Neuron

      Volume: 96(4) Issue: 4 Pages: 730-735

    • DOI

      10.1016/j.neuron.2017.09.028

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Sex differences in avoidance behavior after perceiving potential risk in mice2017

    • Author(s)
      Yokota Sayaka、Suzuki Yusuke、Hamami Keigo、Harada Akiko、Komai Shoji
    • Journal Title

      Behavioral and Brain Functions

      Volume: 13 Issue: 1 Pages: 1-10

    • DOI

      10.1186/s12993-017-0126-3

    • NAID

      120006305829

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Enriched environment and Mash1 transfection affect neural stem cell differentiation after transplantation into the adult somatosensory cortex2017

    • Author(s)
      Arai Mitsunori D.、Zhan Bo、Maruyama Atsuko、Matsui-Harada Akiko、Horinouchi Kazuhiro、Komai Shoji
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 373 Pages: 73-80

    • DOI

      10.1016/j.jns.2016.12.013

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Conditional Spike Transmission Mediated by Electrical Coupling Ensures Millisecond Precision-Correlated Activity among Interneurons In Vivo2016

    • Author(s)
      van Welie Ingrid、Roth Arnd、Ho Sara S.N.、Komai Shoji、Hausser Michael
    • Journal Title

      Neuron

      Volume: 90 Issue: 4 Pages: 810-823

    • DOI

      10.1016/j.neuron.2016.04.013

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modeling and prediction of driving behaviors based on automatic temporal segmentation2016

    • Author(s)
      Ryunosuke Hamada, Takatomi Kubo, Kazushi Ikeda, Zujie Zhang, Tomohiro Shibata, Takashi Bando, Kentarou Hitomi, Masumi Egawa
    • Journal Title

      IEEE Transactions on Intelligent Vehicles

      Volume: 1 Issue: 2 Pages: 131-138

    • DOI

      10.1109/tiv.2016.2586307

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mouse ability to perceive subjective contours.2016

    • Author(s)
      Okuyama-Uchimura, F. and Komai, S.
    • Journal Title

      Perception

      Volume: 45 Issue: 3 Pages: 315-327

    • DOI

      10.1177/0301006615614440

    • NAID

      120005716879

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kinect- based posturography for in- home rehabilitation of balance disorders2015

    • Author(s)
      Tomoya Tamei, Yasuyuki Orito, Hiroyuki Funaya, Kazushi Ikeda, Yohei Okada, Tomohiro Shibata
    • Journal Title

      APSIPA Transactions on Signal and Information Processing

      Volume: 4 Issue: 1 Pages: 1-6

    • DOI

      10.1017/atsip.2015.17

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Variational Bayesian inference algorithms for infinite relational model of network data2015

    • Author(s)
      Takuya Konishi, Takatomi Kubo, Kazuho Watanabe, and Kazushi Ikeda
    • Journal Title

      IEEE Transactions on Neural Networks and Learning Systems

      Volume: to be assigned Issue: 9 Pages: 2176-2181

    • DOI

      10.1109/tnnls.2014.2362012

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Object-based selection modulates top-down attentional shifts2014

    • Author(s)
      Nishida, S., Shibata, T., and Ikeda, K.
    • Journal Title

      Frontiers in Human Neuroscience

      Volume: 8, 125 Pages: 1-8

    • DOI

      10.3389/fnhum.2014.00090

    • NAID

      120005399105

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neural Decoding of Single Vowels during Covert Articulation using Electrocorticography2014

    • Author(s)
      Ikeda S, Shibata T, Nakano, Okada R, Tsuyuguchi N, Ikeda K, Kato A
    • Journal Title

      Front Hum Neurosci

      Volume: epub ahead Pages: 1-8

    • DOI

      10.3389/fnhum.2014.00125

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimating passive dynamics distributions and state costs in linearly solvable Markov decision processes during Z learning execution2014

    • Author(s)
      Mauricio Burdelis, Kazushi Ikeda
    • Journal Title

      SICE Journal of Control, Measurement, and System Integration

      Volume: 7 Issue: 1 Pages: 148-148

    • DOI

      10.9746/jcmsi.7.48

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Computer based automatic identification of abnormal locomotion activity in ASD model mice.2019

    • Author(s)
      Shoji Komai
    • Organizer
      3rd International Conference for Women in science, Cairo, Egypt
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Motion feature-based automatic identification of abnormal locomotion activity of ASD mice.2017

    • Author(s)
      Mohammad Shyful Islam, Satoshi Morimoto and Shoji Komai
    • Organizer
      Society for Neuroscience, 47th Annual Meeting, Washington DC, USA
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Computational behavioral analysis to analyze the effect of microbes on our body.2016

    • Author(s)
      Shoji Komai
    • Organizer
      ICOBM 2016
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Assessing Canine Emotional States Using an Accelerometer2016

    • Author(s)
      R. Ouchi, Y. Maruno, T. Kubo, M. Katayama, M. Nagasawa, T. Kikusui, K. Ikeda
    • Organizer
      ITC-CSCC
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Canine emotional state assessment with heart rate variability2016

    • Author(s)
      Eri Nakahara, Yuki Maruno, Takatomi Kubo, Rina Ouchi, Maki Katayama, Koichi Fujiwara, Miho Nagasawa, Takefumi Kikusui, Kazushi Ikeda
    • Organizer
      APSIPA-ASC
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] In-Home Measurement System of User's Motion and Center of Pressure2015

    • Author(s)
      Tomoya Tamei, Yasuyuki Orito, Tomohiro Shibata and Kazushi Ikeda
    • Organizer
      APSIPA-ASC
    • Place of Presentation
      Hong Kong
    • Year and Date
      2015-12-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] In- Home Measurement System of User’s Motion and Center of Pressure2015

    • Author(s)
      Tomoya Tamei, Yasuyuki Orito, Tomohiro Shibata and Kazushi Ikeda
    • Organizer
      APSIPA- ASC
    • Place of Presentation
      Hong Kong
    • Year and Date
      2015-12-16
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Kinematic and Dynamic Analysis of Sit-to -Stand Transfer Using Hand-to-Hand Assistance by Therapists of Different Skill Levels2015

    • Author(s)
      Lao Bryan, Tamei Tomoya, Kazushi Ikeda
    • Organizer
      計測自動制御学会 システム・情報部門 学術講演会
    • Place of Presentation
      函館
    • Year and Date
      2015-11-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] ガウス過程識別器に基づく視線行動からの 運転熟練者と非熟練者の識別2015

    • Author(s)
      張祖杰,久保孝富,渡辺仁,池田和司,柴田智広,坂東誉司,人見謙太郎, 江川万寿三
    • Organizer
      計測自動制御学会 システム・情報部門 学術講演会
    • Place of Presentation
      函館
    • Year and Date
      2015-11-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] ディープニューラルネットワークの入力符号化能力の情報理論的評価2015

    • Author(s)
      古庄泰隆,久保孝富,池田和司
    • Organizer
      計測自動制御学会 システム・情報部門 学術講演会
    • Place of Presentation
      函館
    • Year and Date
      2015-11-18
    • Related Report
      2015 Annual Research Report
  • [Presentation] Kinematic and Dynamic Analysis of Sit- to- Stand Transfer Using Hand- to- Hand Assistance by Therapists of Different Skill Levels2015

    • Author(s)
      Lao Bryan, Tamei Tomoya, Kazushi Ikeda
    • Organizer
      計測自動制御学会 システム・情報部門 学術講演会
    • Place of Presentation
      函館アリーナ(北海道・函館)
    • Year and Date
      2015-11-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] ガウス過程識別器に基づく視線行動からの 運転熟練者と非熟練者の識別2015

    • Author(s)
      張祖杰,久保孝富,渡辺仁,池田和司,柴田智広,坂東誉司,人見謙太郎, 江川万寿三
    • Organizer
      計測自動制御学会 システム・情報部門 学術講演会
    • Place of Presentation
      函館アリーナ(北海道・函館)
    • Year and Date
      2015-11-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] ディープニューラルネットワークの入力符号化能力の情報理論的評価2015

    • Author(s)
      古庄泰隆,久保孝富,池田和司
    • Organizer
      計測自動制御学会 システム・情報部門 学術講演会
    • Place of Presentation
      函館アリーナ(北海道・函館)
    • Year and Date
      2015-11-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Information Theoretical Analysis of Deep Learning Representations2015

    • Author(s)
      Yasutaka Furusho, Takatomi Kubo, Kazushi Ikeda
    • Organizer
      International Conference on Neural Information Processing
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2015-11-09
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Int'l Joint Research
  • [Presentation] “BEHAVIORAL IMAGING” FOR ANALYZING COMPLEX BEHAVIOR2015

    • Author(s)
      Shoji Komai, Jin Watanabe and Yusuke Suzuki
    • Organizer
      IBRO2015
    • Place of Presentation
      Rio de Janeiro, Brazil
    • Year and Date
      2015-07-10
    • Related Report
      2014 Annual Research Report
    • Int'l Joint Research
  • [Presentation] "Behavioral Imaging" for analyzing complex behavior2015

    • Author(s)
      Shoji Komai, Jin Watanabe and Yusuke Suzuki
    • Organizer
      IBRO2015
    • Place of Presentation
      Rio de Janeiro, Brazil
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Book] 情動の進化2015

    • Author(s)
      駒井章治(渡辺茂・菊水健史編)
    • Total Pages
      192
    • Publisher
      朝倉書店
    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
  • [Book] Methods in Neuroethological Research2013

    • Author(s)
      Cetin A., and *Komai S.
    • Total Pages
      175
    • Publisher
      Springer Japan
    • Related Report
      2013 Annual Research Report

URL: 

Published: 2013-07-10   Modified: 2020-03-30  

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