Budget Amount *help |
¥68,120,000 (Direct Cost: ¥52,400,000、Indirect Cost: ¥15,720,000)
Fiscal Year 2017: ¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
Fiscal Year 2016: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2015: ¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
Fiscal Year 2014: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2013: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
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Outline of Final Research Achievements |
In collaboration with the Medical Science team, Planetary Science team and others, we have developed image reconstruction methods from fewer numbers of measurement data in magnetic resonance imaging (MRI) and very long baseline interferometry (VLBI), in which compressed sensing has been utilized. As an example, using one of the proposed methods, we visualized spatio-temporal dynamics of metabolism of glucose injected into a tumor-bearing mouse in vivo via magnetic resonance spectroscopic imaging (MRSI), where one can observe spreading of the injected glucose over the whole body and conversion into lactate within the tumor tissue (the Warburg effect). Without compressed sensing, it takes several hours to acquire data even for a single frame, making measurement of spatio-temporal dynamics impossible. We have thus proved feasibility of the concept that with compressed sensing one can visualize spatio-temporal dynamics of biochemical processes in body non-invasively.
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