| Budget Amount *help |
¥92,430,000 (Direct Cost: ¥71,100,000、Indirect Cost: ¥21,330,000)
Fiscal Year 2018: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2017: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2016: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2015: ¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2014: ¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
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| Outline of Final Research Achievements |
To clarify the circuit shift mechanism during the recovery from brain and spinal cord injury, we investigated the spinal cord injury and primary visual cortex injury models in macaque monkeys. In the former case, dexterous hand movements recover after the corticospinal tract lesion at C4/C5 segment, and we have demonstrated by using pathway-selective blocking with double viral vector infection technique that the propriospinal neurons in the mid-cervical segments are critically involved in the recovery during the early recovery phase, however during the late recovery phase, other descending pathways also participate in the recovery process and the contribution of propriospinal neurons becomes partial. In the latter case, we have demonstrated by using the same double viral vector infection technique that after the primary visual cortex lesion, the superior colliculus to pulvinar pathway is involved in the recovery of visually guided saccadic eye movements.
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