| Project/Area Number |
01042001
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Special Cancer Research |
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| Research Institution | Gifu University |
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Principal Investigator |
SHIMIZU Hiroyuki Gifu University School of Medicine, 医学部, 教授 (90073139)
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| Co-Investigator(Kenkyū-buntansha) |
ROSS Ronald K. University of Southern California School of Medicine, 医学部, 教授
YATANI Ryuichi Mie University School of Medicine, 医学部, 教授 (80024636)
|
|---|
| Project Period (FY) |
1989
|
| Project Status |
Completed (Fiscal Year 1989)
|
| Budget Amount *help |
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1989: ¥2,000,000 (Direct Cost: ¥2,000,000)
|
|---|
| Keywords | Prostate cancer / Breast cancer / Age at immigration |
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| Research Abstract |
Using age-adjusted incidence rates and proportional incidence ratios, the risks of prostate cancer and breast cancer in two race-ethnicity groups -- Spanish surnamed whites and Japanese -- were studied in Los Angeles County native residents and compared with those in immigrants and representative "homeland" populations. Prostate cancer rates of immigrants were similar to those of US born in the Spanish surnamed white and Japanese populations, regardless of age at immigration. When migration occurred later in life, rates for breast cancer were substantially lower than when migration occurred early; they were still much higher than in the homeland populations. These findings suggest that environmental factors in childhood are especially important in the etiology of breast cancer and that later life events can substantially impact the likelihood of developing clinically detectable prostate cancer.
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