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Phage typing of Stphylococcus aureus by new phages

Research Project

Project/Area Number 01044020
Research Category

Grant-in-Aid for international Scientific Research

Allocation TypeSingle-year Grants
SectionJoint Research
Research InstitutionKitasato University School of Medicine (1991)
Gunma University (1989-1990)

Principal Investigator

INOUE Matsuhisa  Kitasato University School of Medicine, Professor, 医学部, 教授 (10008336)

Co-Investigator(Kenkyū-buntansha) SHATIB W. E.  Indonesia University School of Medicine, Associate Prof., School of Medicin, 助教授
STOBBERINGH E. E.  State University Limberg, Medical, School, Associate Prof., Consultant, Medical School, 助教授コンサルタント
BOVEN C.P.A.  State Univ.Limberg, Medical School, 教授
VAN BOVEN C. P. A.  State University Limberg, Medical School, Prefessor
CHATIB W.E  インドネシア大学, 医学部, 助教授
SAOBBERINGH  州立リンバーグ大学, 医学部, 主任研究員
Project Period (FY) 1989 – 1991
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥4,400,000 (Direct Cost: ¥4,400,000)
Fiscal Year 1991: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1990: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1989: ¥1,700,000 (Direct Cost: ¥1,700,000)
KeywordsInternational basic phages / K phages / MSSA / MRSA / Phage typing / 血清型 / コアグラ-ゼ型 / ファ-ジ型別 / 型別不能
Research Abstract

This report describes the-extraction of phages from methicillin-resistant and -susceptible Stapylococcus aureus (MRSA, MSSA) isolates throughout in Japan, and evaluation of this phage set as an aid to the recognition of isolates of the Japanese epidemic MSSA and MRSA. Fifteen experimental phages called K phages, were derived by mitomycin-C induction from MSSA and MRSA. They were assessed for their ability to distinguish, isplated of a MRSA epidemic including MSSA in the different area of this country from other strains such ai the isolates in the Netherland, the Indonesia and the Hungary. The experimental phages were more active against strains of phage groups III, III+I and NT (not. tkpable groups). Out of 50% or more not typable strains by International based set phages, about 80% or more of those strains were typable by the K phages.
It was decided that 8 or 9 K phages might be used to distinguish, , . isolates of MSSA and MRSA which derive from clinical specimen. The K phages will be tested by the committee in the future.

Report

(2 results)
  • 1991 Final Research Report Summary
  • 1990 Annual Research Report
  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] 井上 松久,大久保 豊司,橋本,一: "本邦・東欧・インドネシア由来MRSAの耐性型等について" Chemotherapy. 39. 281-281 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 大久保 豊司,橋本 一,井上 松久: "黄色ヴドウ球菌のファ-ジ型別化の検討" 日本細菌学雑誌. 47. 281-281 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 井上 松久: "黄色ブドウ球菌の薬剤耐性" 埼玉医師会誌. (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] M.Inoue,T.Okubo,E.E.Stobberingh,and W.E.Chatib: "Supplementary phages for the invesitgation of Strains of Staphylococcus aureus" J.Medical.Microbiol.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T.Okubo and M.Inoue: "Bocteriological characters of strains of Staphylococcus aureus" J.Antimicrob.Chemotherd.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Matsuhisa Inoue, Toyoji Okubo and Hajime Hashimoto: "Resistance Patterns of MRSA isolated from in Japan and East Europe (in Japanease)" Cemotherapy. 39. 281-281 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Toyoji Okubo, Matsuhisa Inoue and Hajime Hashimoto: "Phage typing in Satphylococcus aureus ioolated from patients (in Japanease)" Japanease J. Microbiol.47. 281-281 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Matsuhisa Inoue: "Drug resistance in Staphylococcus aureus (in Japanease)" Saitama Medical J.(1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Matsuhisa Inoue, Toyoji Okubo, Ellen E. Stobberingh and Warsa E. Chatib: "Supplementary phages for the investigation of strains of Staphylococcus aureus." J. Medical Microbiol.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Toyoji Okubo and Matsuhisa Inoue: "Bacteriological characters of strains of Staphylococcus aureus" J. Antimicrob. Chemother.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 井上 松久 大久保 豊司: "黄色ブドウ球菌のファ-ジ型別法" 検査と技術. 17. 1611-1615 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 井上 松久、大久保 豊司: "本邦分離の黄色ブドウ球菌の薬剤耐性型とファ-ジ型別" Chemotherapy.

    • Related Report
      1990 Annual Research Report
  • [Publications] M. Inoue et. al.: "Phage typing of S. aureas by new phages." Med. Microbiol.

    • Related Report
      1990 Annual Research Report
  • [Publications] 井上 松久: "薬剤感受性情報(耐性菌情報)1988・1989年版" (財)医療情報システム開発センタ-, 69-132 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 井上 松久: "薬剤感受性情報(耐性菌情報)1990年版" (財)医療情報システム開発センタ-, 45-67 (1990)

    • Related Report
      1990 Annual Research Report

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Published: 1989-04-01   Modified: 2016-04-21  

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