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Hormonal control of migration in salmon

Research Project

Project/Area Number 01044162
Research Category

Grant-in-Aid for Overseas Scientific Survey.

Allocation TypeSingle-year Grants
Research InstitutionUniversity of Tokyo

Principal Investigator

HIRANO Tetsuya  Ocean Research Institute, University of Tokyo, 海洋研究所, 教授 (70013571)

Co-Investigator(Kenkyū-buntansha) IVES Vallota  レンヌ大学, 分子生物学教室, 教授
PATRICK Prun  フランス国立農林水産研究所(INRA), 主任研究員
IKUTA Kazumasa  Ocean Research Institute, University of Tokyo, 海洋研究所, 特別研究員 (30201908)
URANO Akihisa  Ocean Research Institute, University of Tokyo, 海洋研究所, 助教授 (00142232)
PRUNET Patrick  Laboratory of Physiology, National Institute of Agriculture
VALLOTAIRE Yves  Department of Molecular Biology, University of Rennes
Project Period (FY) 1989
Project Status Completed (Fiscal Year 1989)
KeywordsSalmonid fish / Migration / Endocrine system / Growth hormone / Prolactin / Osmoregulation / Hormone receptors / Recombinant DNA
Research Abstract

The endocrine systems have important roles in controls of various aspects of fish migration. It is well accepted that, in salmonid fish, prolactin is a hormone necessary for fresh water adaptation, while growth hormone is responsible for seawater adaptation. Nonetheless, we do not know modes of actions of these hormones in migratory fish, mainly because of a lack of homologous hormones. Recent progress in molecular biology now makes it possible to have micro-organisms synthesize so-called recombinant hormones which in turn allow us to conduct receptor studies, such as a radio receptor assay (RRA). In the present project, we therefore tried to apply molecular techniques in a study on endocrine mechanisms of salmon migration. Since recombinant salmon growth hormone is available, a radio receptor assay system was rather easily established to examine physiological changes in its kinetics. Contrary, recombinant salmon prolactin is not available, so that tilapia whose hormone is available was used to establish prolactin RRA.

Report

(1 results)
  • 1989 Final Research Report Summary

URL: 

Published: 1993-03-26   Modified: 2016-04-21  

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