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Studies on the pathogenesis of the disturbed integration of functions in both hemispheres of the functional psychoses

Research Project

Project/Area Number 01304040
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionKanazawa University

Principal Investigator

YAMAGUCHI Nariyoshi  Kanazawa University School of Medicine Department of Neuropsychiatry Professor, 医学部, 教授 (00064501)

Co-Investigator(Kenkyū-buntansha) KURACHI Masayoshi  Toyama Medical and Pharmaceutical University Department of Neuropsychiatry Profe, 医学部, 教授 (80019603)
TAKAHASHI Saburo  Shiga University of Medical Science Department of Psychiatry and Neurology Profe, 医学部, 教授 (20079916)
NIWA Shin-ichi  Tokyo University Faculty of medicine Department of Neuropsychiatry Instructor, 医学部, 助手 (30110703)
KOJIMA Takuya  Tokyo Medical and Dental University Department of Neuropsychiatry Assistant Prof, 医学部, 講師 (40014203)
SATO Mitsumoto  Tohoku University School of Medicine Department of Neuropsychiatry Professor, 医学部, 教授 (70033321)
Project Period (FY) 1989 – 1990
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥10,600,000 (Direct Cost: ¥10,600,000)
Fiscal Year 1990: ¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 1989: ¥5,600,000 (Direct Cost: ¥5,600,000)
KeywordsFunctional psychosis / Disturbed integration of functions in both hemispheres / Cognition disorder / Event-related potential / Regional cerebral blood flow / Continent negative variation / Neuroimaging / Eye movements / 睡眠脳波のトポグラフィ- / 神経心理学
Research Abstract

The etiology of the functional psychoses such as schizophrenia and mood disorder is not clear. It is assumed that there is the disturbed integration of function in both hemispheres in the functional psychoses. We have tried this research for the purpose to clear the etiology of the functional psychoses by using the neuropsychological, neurophysiological, and neuroimaging methods.
Yamaguchi and Kurachi studied the relationship between frontal blood flow and clinical findings in schizophrenic patients. Compared with the normal controls, the patients showed a reduced relative frontal flow in the left hemisphere. Sato and Kojima investigated the eye fixations and movements during maze test in schizophrenia. Yamauchi investigated an asymmetry of EEG background activity in schizophrenia. Niwa and Machiyama studied the auditory event-related potentials in schizophrenia. Takahashii investigated the CNV in depression. Hozaki and Torn performed neuropsychological investigations on chronic schizophrenia from aspects of its frontal function.

Report

(3 results)
  • 1991 Final Research Report Summary
  • 1990 Annual Research Report
  • 1989 Annual Research Report
  • Research Products

    (30 results)

All Other

All Publications (30 results)

  • [Publications] 鳥居 方策,北本 福美: "痴呆の神経心理学ー特に言語障害を中心にー" 老年期痴呆研究会誌. 3. 21-26 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 佐藤 光源: "精神分裂病の再発をめぐる諸問題" 日精協雑誌. 9. 12-19 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 山口 成良: "ベンゾジアゼピン依存" 神経精神薬理. 13. 90-94 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 倉知 正佳,湯浅 悟,鈴木 道雄: "精神分裂病と画像診断ー局所脳血流を中心にー" 精神医学. 32. 609-617 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 寺崎 太洋,大久保 善郎,松浦 雅人,小島 卓也: "精神分裂病患者脳波の定量的研究ー局所定常自己回帰モデルを用いた定常性の検討ー" 精神薬療基金研究年報. 21. 264-269 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 丹羽 信一: "分裂病の病態理解への精神生理学的接近" 精神医学. 32. 591-596 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 山口 成良,越野 好文: "誘発電位の基礎と臨床" 創造出版,東京, 1-68 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 地引 逸亀,山口 成良: "てんかん学の進歩NO.2ー1991" 岩崎学術出版社,東京, 181-197 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Niwa, S.: "Psychophysiological understanding of assumed neuronal basis of schizophrenia : Expectation for future possibilities." Seishin Igaku (Clinical Psychiatry). 32(6). 591-596 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Fukuda, M., Niwa, s. -I., et al.: "Psychological intervention can partly alter P300-amplitude abnormalities in schizophrenics." Jpn J Psychiatr Neurol. 43(4). 633-638 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Fukuda, M., Niwa, s. -I., et al.: "Psychological manipulation of P300 amplitude abnormalities in schizophrenics : Reconfirmation and extension of our previous result." ANN. Bull. RILP. 24. 243-256 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Kurachi, M., et al.: "Schizophrenia and brain imaging." Seishin Igaku (Clinical Psychiatry). 32(6). 609-617 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Kurachi, M.: "Biopsychological regions hitherto called endogenous." Japanese Journal of Psychopathology. 11(3). 197-204 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yuasa, S., Kadono, Y., Tsunoda, M., Matsui, M., Emori, K., Minabe, Y., Fujii, T., and Kurachi, M.: "SPECT finding in schizophrenia : clinical correlates and the effect of neuroleptic treatment." Japanese Journal of Clinical Psychiatry. 19(12). 1840-1848 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Terasaki, O., Okubo, Y., Matsuura, M., and Kojima, T.: "A quantitative study on stationarity of EEGs of schizophrenics using locally stationary autoregressive model." Annual Report of the Pharmacopsychiatry Research Foundation. 21. 264-269 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Torii, H. and Kitamoto, F.: "Neuropsychological features of dementia of the Alzheimer type, with special reference to dysphasia." Proceedings of the Annual Meeting of the Japanese Research Group on Senile Dementia. 3. 21-26 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Jibiki, I. and Yamaguchi, N.: "Investigation of auditory brainstem responses and visual evoked potentials to pattern reversal stimulations in medicated schizophrenic patients." Jpn J EEG EMG. 18(4). 387-393 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 倉知 正佳,湯浅 悟,鈴木 道雄: "精神分裂病と画像診断ー局所脳血流を中心にー" 精神医学. 32. 609-617 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 倉知 正佳: "内因性と呼ばれた生物心理学的領域について" 臨床精神病理. 11. 197-204 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 寺崎 太洋,大久保 善朗,松浦 雅人,小島 卓也: "精神分裂病患者脳波の定量的研究ー局所定常自己回帰モデルを用いた定常性の検討ー" 精神薬療基金研究年報. 21. 264-269 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Fukuda,M.,Niwa,S.,Hiramatsu,K.et.al.: "Psychological manipulation of P300 amplitude abnormalities in schizophrenics:reconfirmation and extension of our previous result" Ann.Bull.RILP.24. 245-256 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 丹羽 信一: "分裂病の病態理解への精神生理学的接近" 精神医学. 32. 591-596 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 倉知 正佳: "金沢大学医学部神経精神医学教室80年のあゆみ 精神分裂病への臨床的・基礎的アプロ-チ" 金沢大学医学部神経精神医学教室, 117 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 松岡洋夫,佐藤光源: "図形および文字の情報処理に関係する事象関連電位 ー内因性陰性電位を中心にー" 臨床脳波. 32. 166-170 (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] 中島一憲,小島卓也,松島英介,大林滋,上杉秀二,大沼悌一,大高忠,島薗安雄: "側頭葉てんかん患者の開瞼時眼球運動 ー発作波焦点側との関連性を中心にしてー" 精神医学. 31. 1157-1164 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Fukuda,M.,Niwa,S.,Hiramatsu,K.,Hayashida,S.,Saitoh,O.,Kameyama,T.,Nakagome,K.,Iwanami,A.,Sasaki,T.and Itoh,K.: "Psychological Intervention Can Partly Alter P300 Amplitude Abnormalities in Schizophrenics" Jpn J Psychiatry Neurol. 43. inpress (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 久保田文雄(町山幸輝指導): "うつ病における聴覚事象関連電位:状態依存性および大脳半球機能障害についての検討" 北関東医学. 39. 63-74 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 狩野正之(町山幸輝指導): "精神分裂病における局所脳血流量の研究" 北関東医学. 39. 485-499 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 鈴木道雄(山口成良指導): "機能性精神障害の局所脳血流と臨床所見との対応について I.精神分裂性障害患者における検討" 金沢大学十全医学会雑誌. 97. 764-778 (1988)

    • Related Report
      1989 Annual Research Report
  • [Publications] 倉知正佳: "精神分裂病への臨床的・基礎的アプロ-チ 金沢大学医学部神経精神医学教室80年のあゆみ" 金沢大学医学部神経精神医学教室, 117 7-14 (1990)

    • Related Report
      1989 Annual Research Report

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Published: 1989-04-01   Modified: 2016-04-21  

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