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Comprehensive Study on the Effective Use of Laboratory Animals which have been Developed and held in Different Institutions

Research Project

Project/Area Number 01304055
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Laboratory animal science
Research InstitutionKanazawa University

Principal Investigator

HAYAKAWA Jun-ichiro  Kanazawa University School of medicine Associate Professor, 医学部, 助教授 (50110622)

Co-Investigator(Kenkyū-buntansha) KASAI Magosaburo  Kouchi University, College of Agriculture, Associate Professor, 農学部, 助教授 (60152617)
KASAI Noriyuki  Hokkaiko University School of Medicine Associate Professor, 医学部, 助教授 (60001947)
KAGIYAMA Naoko  Central Institute for Laboratory Animals, Laboratory Animal Medicine, Chief, 室長 (50124269)
HANDA Sumio  Kyushu University School of Medicine Associate Professor, 医学部, 助教授 (50037503)
MORIWAKI Kazuo  National Institute of Genetics Cytogenetics, Professor, 細胞遺伝研究部門, 教授 (50000229)
西村 正彦  浜松医科大学, 医学部, 助教授 (20073661)
豊田 裕  東京大学, 医科学研究所, 教授 (90050418)
山田 淳三  京都大学, 医学部, 教授 (90025651)
Project Period (FY) 1989 – 1990
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥10,800,000 (Direct Cost: ¥10,800,000)
Fiscal Year 1990: ¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 1989: ¥5,800,000 (Direct Cost: ¥5,800,000)
KeywordsLaboratory animals / Information / Database / Microbiology / Genetics / Embryo freezing / Embryo transportation / 疾患モデル / デ-タ・ベ-ス
Research Abstract

The results of this two-year co-operative research indicate that at the present the following methods on information, quality control, transportation of laboratory animals are best for the mutual utilization of the animals between the different institutions.
(1) Construction and use of database. The distribution of diskette which is operated by MS-DOS is the most effective to use the database on the laboratory animals, because most institutions have installed microcomputers which operated by the system but not on-line operated computer system.
(2) Quality control of animals. ELISA kit for the detection of the antibodies against the specific pathogens is simple and effective for microbiological quality control. Enzyme electrophoresis by a simple device which developed during this research could be used for genetic quality control of mice and rats.
(3) Transportation of animals. Non-frozen and frozen embryos can be transferred between the institutions. The methods are promised future use for the transportation of animals.

Report

(3 results)
  • 1991 Final Research Report Summary
  • 1990 Annual Research Report
  • 1989 Annual Research Report
  • Research Products

    (24 results)

All Other

All Publications (24 results)

  • [Publications] T.Koizumi,M.Katsuki,M.Kimura,J.Hayakawa: "Localization of the gene encoding myelin basic protein in mouse chromosome 18E3→4 and rat chromosome 1p11→p12." Cytogenetics & Cell Genetics.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] S.Tanaka,K.Moriwaki et al.: "Gene responsible for deficient activity of the subunit of C8,eighth component of complement,is located on chromosome 4." Immunogenetics. 33. 18-23 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T.Higashiguchi,J.Yamada et al.: "Identification of inbred strains of rats by DNA fingerprints using chemiluminescence." Transpl.Proc.22. 2564-2565 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] N.Kagiyama et al.: "Studies on the development of an ELISA kit for microbiological monitoring.Evaluation of the reliability of prototype kit by field test." Exp.Anim.39. 89-96 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T.Miyoshi,N.Kasai et al.: "Useful short-range transport of mouse embryos by mean of a nonfreezing technique." Laboratory Animal Sci.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] M.Kasai et al.: "A simple method for mouse embryo cryoreservation in a low toxicity viteification solution,without appreciable loss of viability." J.Reprod.Fert.89. 91-97 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T. Koizumi, M. Katsuki, M. Kimura and J. Hayakawa: "Localization of the gene encoding meyelin basic protein in mouse chromosomes and rat chromosomes" Cytogenetics & Cell Genetics. (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] S. Tanaka, K. Moriwaki et al.: "Gene responsible for deficient activity of the subunit of C8, eighth component of complement is located on chromosome 4." Immunogenetics. 33. 18-23 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T. Higashiguchi, J. Yamada et al.: "Identification of inbred strains of rats by DNA fingerprints using chemiluminescence." Transpl. Proc.22. 2564-2565 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] N. Kagiyama et al.: "Studies on the development of an ELISA kit for microbiological monitoring. Evaluation of reliability of prototype kit by field test." Exp. Anim.39. 89-96 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T. Miyoshi, N. Kasai et al.: "Useful short-range transport of mouse embryos by means of a nonfreezing technique" Laboratory Animal Science.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] M. Kasai et al.: "A simple method for mouse embryo cryoreservation in a low toxicity vitrification solution, without appreciable loss of viability." J. Reprod. Fert.89. 91-97 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T.Koizumi;M.Katsuki;M.Kimura;J.Hayakawa: "Localization of the gene encoding myelin basic protein in mouse chromosome 18E3 4 and rat chromosome 1p11 p12" Cytogenetics & Cell Genelics (inpress). (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] S.Tanaka;K.Moriwaki;et al.: "Gene responsible for deficient activity of the subunit of C8,eight component of complement,is located on chromosome 4" Immunogenetics. 33. 18-23 (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] T.Higashiguchi;J.Yamada et al.: "Identification of inbred strains of rats by DNA fingerprints using chemiluminescence" Transpl.Proc.22. 2564-2565 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] N.Kagiyama et al.: "Studies on the development of an ELISA kit for microbiological monitoring.Evaluation of the reliability of prototype kit by field test" Exp.Anim.39. 89-96 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] T.Miyoshi N.Kasai,et al.: "Useful shortーrange transport of mouse embryos by means of a nonfreezing technique" Laboratory Animal Sci.

    • Related Report
      1990 Annual Research Report
  • [Publications] M.Kasai et al.: "A simple method for mouse embryo cryoreservation in a low toxicity verification solution,without appreciable loss of viability" J.Reprod.Fert.89. 91-97 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] K.Koizumi,J.Hayakawa,H.Nikaido: "Blood ammonia concentration in mice:normal reference values and changes during growth." Laboratory Animal Science. 40. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] T.Sagai,F.Bonhomme,K.Moriwaki,et al.: "New evidence for trans-species evolution of the H-2 class I polymorphism." Immunogenetics. 30. 89-98 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] T.Yamada,M.Mori,J.Yamada,et al.: "Assignment of body tremorous mutant gene zitter(zi) to linkage group IV of the rat(Ratus norvegicus)." J.Heredity. 80. 383-386 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] H.Kobayashi,T.Watanabe,S.Handa: "Vertebral abnormalities following heat shock in Xenopus embryo." Developmental Growth and Differentiation. 31. 65-70 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Y.Toyoda: "Effect of chelating agents on preimplantation development of mouse embryos fertilized in vitro." Prog.Clin.Biol. Res.294. 171-179 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] M.Nishimura,M.Inoue,Y.Kitamura,et al.: "Beige rat: a new animal model of Chediak-Higashi syndrome." Blood. 74. 270-273 (1989)

    • Related Report
      1989 Annual Research Report

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Published: 1989-04-01   Modified: 2016-04-21  

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