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Studies on Treatment of Abnormal Binocular Functions in Amblyopia and Strabismus in Infants

Research Project

Project/Area Number 01440073
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Ophthalmology
Research InstitutionNagoya University

Principal Investigator

AWAYA Shinobu  Nagoya Univ. School of Med. Professor, 医学部, 教授 (00023755)

Co-Investigator(Kenkyū-buntansha) TANAKA Hiroto  Nagoya Univ. School of Med. Instructor, 医学部, 助手 (50227170)
TSUZUKI Kinichi  Nagoya Univ. School of Med. Instructor, 医学部, 助手 (70197739)
YAGASAKI Teiji  Nagoya Univ. School of Med. Instructor, 医学部, 助手 (50191078)
KARAKI Takeshi  Nagoya Univ. School of Med. Assist. Rrof., 医学部, 講師 (90224708)
MIYAKE Sampie  Nagoya Univ. School of Med. Assist. Rrof., 医学部, 講師 (40115639)
矢ケ崎 克哉 (矢ヶ崎 克哉)  名古屋大学, 医学部, 講師 (70174480)
Project Period (FY) 1989 – 1991
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥16,500,000 (Direct Cost: ¥16,500,000)
Fiscal Year 1991: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1990: ¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 1989: ¥12,100,000 (Direct Cost: ¥12,100,000)
KeywordsBinocular function / Stereoacuity / Strabismus / Amblyopia / Static random dot / Dynamic random dot / Checkerboard pattern stimulator / Sensitive period / static randomーdot pattern / dynamic randomーdot pattern / monocular cue / Checkerboard pattern刺激 / 内斜視 / 外斜視 / Static Random Dot / Dynamic Random Dot / TVーR.D.ステレオテスト / チェッカ-・ボ-ド・パタン刺激 / VEP
Research Abstract

For the occurrence and. development of the stereopsis, visual acuity. in each eye, aniseikonia between the iwo eyes-. ocular alignment, and binocular cells'in the visual cortex are four cardinal factors. Studies have been-made on these paramenters in order to dxplore effective methods to prevent and treat abnormal development of this important'function. (1) Visual acuity in infants : testing methods and nomal development. The comparison of measurement of visual acuity in infants by the conventional preferential. looking (PL) and the Teller Acuity Card (TAC) proved higher level of acuity by TAC in infants aging up to the 12th month after birth, and the essentially same measurements were obtained by these two methods in infants over this age. (2) Stereoacuity in infants : testing methods and normal development. IIt is very important to quantitatively measure stereoacuity in infants within 24 months after birth, which is likely to be very susceptible in the sensitive period of visual function. Fort this purpose the TV-Randon dot stereo test, which was developed by the author in 1987, is very effective in auantitative evaluation bf stereoacuity in infants. Our studies with this instrument demonstrated that stereopsis starts to develop in infants around the 3rd or 4th month of, , age and reach the level of 550" or better by the end of three years of age. In order to elucidate the complicated patho-physiological mechanism of stereopsis, visual evoked potential (VEP) W-as studied by theistatic and dynamic random dot stereo patterns disclosed only. 3, 0 percent of the cases examined showed stereo VEP by the dynamic pattern, while 80 percent of the cases showed a positive response by the static patterns. Further studies are to be made. Concluding from these data mentioned above, simultaneous stimulation of the foveolas with the same stimuli by the "Checkerboard Pattern stimulator" in order to cultivate and enhance stereoacuity under normal visual environment

Report

(4 results)
  • 1991 Annual Research Report   Final Research Report Summary
  • 1990 Annual Research Report
  • 1989 Annual Research Report
  • Research Products

    (39 results)

All Other

All Publications (39 results)

  • [Publications] Shinobu Awaya,Yasuhiko Mizukami,Ayumi Kamiya,Eriko Koizumi & Sampei Miyake.: "Studies of Stereoacuity in Infants by the TV-Random Dot Stereo Test" Strabismus and Ocular Motility Disorders(Proceedings of the Sixth Meeting of the International Strabismological Association)Edited by Emilio Campos. 109-114 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya: "AMBLYOPIA:Update Concept,Classification and Diagnosis." Journal of the Spanish Strabismological Society. (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya,Teiji Yagasaki & Yasuko Inagaki: "Effect of the "CHECKERBOARD PATTERN STIMULATOR"on Binocular Vision in Exotropia." Transactions of the XXVI International Congress of Ophthalmology. (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 粟屋 忍: "乳幼児の立体視の発達とその検査法" 日本眼科紀要. 40. 1-8 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 岡田 祐子,吉岡 均,三宅 三平,粟屋 忍: "生直後の片目完全閉瞼例の視機能" 眼科臨床医報. 84. 330-332 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 岡田 祐子,粟屋 忍他: "Teller Acuity Cardsによる幼児の視力検査" 眼科臨床医報. 85. 1224-1227 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 粟屋 忍(分担): "眼の病変各科臨床医のために「弱視」(稲富 昭太,宇山 昌延,所 敬,井村 裕夫編)" 金芳堂, 337 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 粟屋 忍(分担): "眼科治療クイックガイド「小児眼科疾患」(増田 寛次郎,本田 孔士編)" 医学書院, 470 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Ahinobu Awaya, Yasuhiko Mizukami, Ayumi Kamiya, Eriko Koizumi, and Sampei Miyake: "Studies of Stereoacuity in Infants by the TV-Random Dot Stereo Test." Strabismus and Ocular Motility Disorders (Proc. of the VIth Meeting of the Int. Strabismol. Assoc.). Ed. E. Campos.109-114 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya: "AMBLYOPIA : Update Concept, Classification and Diagnosis." Journal of Spanish Strabismological Association.(1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya: "AMBLYOPIA : Update Concept, Classification and Diagnosis." Journal of Spanish Strabismological Association.(1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya, Teiji Yagasaki and Yasuko Inagaki: "Effect of the "Checkerboard Pattern Stimulator" on Binoculat Vision in Exotropia." Transactions of the XXVI International Congress of Ophthalmology. (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya: "Development and Assessment of Stereopsis in Infants" Folia Ophthalmologica Jpn.40. 1-8 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yuko Okada, Hitoshi Yoshioka, Sampei Miyake and Shinobu Awaya: "Visual Function in Infants with Temporary Complete Lid Closure after Birth." Jpn Rev Clin Ophthalmology. 84. 330-332 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yuko Okada, Shinobu Awaya, Teiji Yagasaki, Yoshie Ozeki, Atsuko Takashi and Toshie Hirai: "Assessment of Visual Acuity In Infants by the Teller Acuity Card." Jpn Rev Clin Ophthalmology. 85. 1224-1227 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya: Kimpodo Publishing Company. AMBLYOPIA In "OCULAR FINDINGS for Medical Practioners., 337 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya: Igaku Shoin Publishing Company. Diseases in Pediatric Ophthalmology. In "GUIDEBOOK IN OPHTHALMIC TREATMENT", 470 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Shinobu Awaya: "Amblyopia:Update Concept, Classification and Diagnosis" Presented at the 1991 Annual Congress of Spanish Strabismological Society Submitted to Journal of Spanish Strab. Society. (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Shinobu Awaya,Toshimasa Tanaka,Yoshie Ozeki and Shigetaka Yamamoto: "Measurement of Cyclodeviation by the New Cyclo Tests." Transactions of XII AsiaーPacific Academy of Ophthalmology. (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Shinobu Awaya,Teiji Yagasaki,Miho Sato and Takeshi Karaki: "Measurement of Cyclodeviation in the Diagnostic Positions of Gaze." Presented at the 18th Annual Meeting of the American Assoc. for Pediatric Ophthalmology and Strabismus. (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] 矢ケ崎 悌司,粟屋 忍,高士 敦子,平井 淑江: "先天白内障術後症例の視機能の検討" 眼科臨床医報. 85. 195-202 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 田中 浩人,粟屋 忍,林 博文: "先天性無虹彩症の両眼視機能について" あたらしい眼科. 8. 463-466 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 中村 富雄,粟屋 忍,三宅 三平: "AーV型斜視における水平筋附着部異常及び斜掛機能異常について" 日本眼科学会雑誌. 95. 698-679 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 粟屋 忍(分担)(稲富 昭太,宇山 昌延,所 敬,井村 裕夫,編): "眼の病変 各科臨床医のために 「弱視」" 金芳堂, 337 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 粟屋 忍(分担)(増田 寛次郎,本田 孔士編): "眼科治療クイックガイド 「小児眼科疾患」" 医学書院, 470 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Shinobu Awaya,et al: "Studies of stereoacuity in infants by the TVーRandom Dot Stereo Tests" Strabismus and ocular motility disorders Proceedings of the 6th meeting of the Int.Strab.Assoc.109-114 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 矢ケ崎 悌司,粟屋 忍,他: "先天白内障手術の検討ー合併症と視力予後ー" 眼科臨床医報. 85. 431-437 (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 矢ケ崎 克哉,粟屋 忍,他: "暗順応・明順応視野測定の臨床応用 1)装置の試作" 日本眼科学会雑誌. 94. 1162-1168 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 岡田 祐子,吉岡 均,三宅 三平,粟屋 忍: "生直後の片眼完全閉瞼例の視機能" 眼科臨床医報. 84. 330-332 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 水上 寧彦,粟屋 忍,他: "TVーRandom Dot Stereo Testによる乳幼児の立体視の研究ーその後の検討" 日本眼科学会. 95. (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 岡田 祐子,粟屋 忍,他: "Teller Acuity Cardsによる乳幼児の視力検査" 眼科臨床医報. 85. 1224-1227 (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 増田 寛次郎・本田 孔士編,粟屋 忍(分担): "疾患別眼治療マニュアル「小児眼科」" 医学書院, (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 稲富 昭太、宇山 昌延、所 敬編,粟屋 忍(分担): "一般臨床医のための眼病変の知識「弱視」" 金芳堂, (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 粟屋忍: "乳幼児の立体視の発達とその検査法" 日本眼科紀要. 40. 1-8 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] 粟屋忍: "小児眼科疾患の検査法とその特徴" 小児眼科. 21. 475-477 (1989)

    • Related Report
      1989 Annual Research Report
  • [Publications] Shinobu Awaya,et al: "Studies of Stereoacuity in Infants by the TV-Random Dot Stereo Test(第6回国際斜視学会発表)" 第6回国際斜視学会 Transactions.

    • Related Report
      1989 Annual Research Report
  • [Publications] Shinobu Awaya,et al: "Effect of the “Checkerboard Pattern Stimulator on Binocular in Exotropia"(第26回国際眼科学会発表)" 第26回国際眼科学会 Transactions.

    • Related Report
      1989 Annual Research Report
  • [Publications] Teiji Yagasaki: "The influence of epiblepharon with inverted eye-lashes(entropium ciliare)on visual function(第26回国際眼科学会発表)" 第26回国際眼科学会 Transactions.

    • Related Report
      1989 Annual Research Report
  • [Publications] 矢ヶ崎克哉: "暗順応・明順応perimeterの臨床応用 1)装置の試作" 日本眼科学会誌.

    • Related Report
      1989 Annual Research Report

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Published: 1989-04-01   Modified: 2016-04-21  

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