BANNO Yutaka Faculty of Agriculture Kyushu University, 農学部, 助手 (50192711)
KIHARA Hzime Faculty of Agriculture Kyushu University, 農学部, 助手 (70089944)
KAWAGUCHI Yutaka Faculty of Agriculture Kyushu University, 農学部, 助教授 (80038306)
FUJII Hiroshi Faculty of Agriculture Kyushu University, 農学部, 助教授 (10038268)
|Budget Amount *help
¥6,900,000 (Direct Cost: ¥6,900,000)
Fiscal Year 1991: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1990: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1989: ¥4,700,000 (Direct Cost: ¥4,700,000)
The Silkworm Genetics Division of the Institute of Genetic Resources, Kyushu University, is the largest and most active stock-center of Borbyx mori. Mutant stocks under maintenance amount to 450, more than 90% of gene mutations presently in existence are involved. In pursuit of unknown genetic variations suitable for researches in modern life-science, more refined knowledge on genetic information concerning the basic aspects of life history have been obtained and analyzed genetically. Some of them are expected to be useful as the model animals of human diseases. Mating experiments have revealed 2 new linkage groups and 33 new gene loci on the genetic maps.
1. New linkage groups discovered
(1) Group 26 : so and nm-i. (2) Group 27 : Xan, l-li and Ym.
2. Morphological. physiological and behavioral mutations
Egg formation (emi, vit). Lethal as embryo (l-br_2). Lethal as young larva (nm-k, nm^n, nm-x nm-i). Lethal before onset of reproductive growth (l-li). Growth rate (Rg-q, Slg^D). Body color and appendage (E^<Es>, U^N, so, Xan, Ym). Cocoon color (Gd, Gf, Gh, Gi). Cocooning behavior (San, cru). Wing differentiation (fl^n, cl). Gonad differentiation (gap, gon). Life-span (eph). Mutation inducer (mu-oal).
3. Protein polymorphism
(1) Chymotrypsin-inhibitory protein (Ict-A. Ict-D, Ict-E). (2) Hemolymph protein in early development (Py1, Py1-2). (3) Egg-specific protein (Pes).
4. Chromosomal attachment
T(23 ; 25)Nd, T(6 ; 7)E^<DS>, T(6 ; 20)E^<NP>.
Attempt to develop a system to use this species of insect as an alternative experimental animal for teratogenicity tests could not be attained yet, further studies are needed to lay open fresh avenue.