An experimental research on skull-surface recording of vestibular evoked potentials
| Project/Area Number |
01480409
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Kyushu University |
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Principal Investigator |
UEMURA Takuya Kyushu University, Faculty of Medicine, Professor., 医学部, 教授 (00075201)
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| Project Period (FY) |
1989 – 1990
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| Project Status |
Completed (Fiscal Year 1991)
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| Budget Amount *help |
¥5,700,000 (Direct Cost: ¥5,700,000)
Fiscal Year 1990: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1989: ¥5,000,000 (Direct Cost: ¥5,000,000)
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| Keywords | Evoked potential / Rotatory stimulation / Vestibular system / Guinea pig / Unit recording / Labyrinthectomy |
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| Research Abstract |
Rotational evoked potentials were studied in the guinea pig under urethane anesthesia. The stimulus events were triangular velocity changes produced by abrupt reversals of acceleration, and horizontal semicircular canals were stimulated. A positive-negative-positive (P_1-N_1-P_2) wave was recorded in the vestibular nuclei and the potential was totally abolished after bilateral labyrinthectomy. Single unit recordings revealed that the peak latency of the negative wave is almost coincident with the peak latency of the excitation of type I vestibular nucleus neurons. It is concluded that the recorded potential to the rotational stimuli in this experiment is of vestibular origin. P_1-N_1-P_2 waves similar to those in the Brainstem were recorded on the occipital portion of the cerebral surface and cerebellar surface. These waves were also abolished after bilateral labyrinthectomy. It is suggested that the vestibular evoked potentials is able to record on the brain surface.
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Report
(3 results)
Research Products
(3 results)
