| Co-Investigator(Kenkyū-buntansha) |
UEHARA Shigechika School of Dentistry, Niigata University, Assistant, 歯学部, 助手 (80176627)
KANATANI Mitsugu School of Dentistry, Niigata University, Assistant, 歯学部, 助手 (40177499)
渡辺 明彦 新潟大学, 歯学部, 助手 (50201166)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥5,200,000)
Fiscal Year 1990: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1989: ¥4,200,000 (Direct Cost: ¥4,200,000)
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| Research Abstract |
In the clearance method using electrolytically generated hydrogen gas (electrolytic method), hydrogen gas is generated by applying current to the inserted electrode in the tissue. We estimate the amount of local blood flow by its clearance curve. However, there is an inherence in this method because measurement values vary according to the conditions under which in the measurements themselves were taken. For example, the electrolytic current intensity (Id) and electrolytic current duration (Td) which we call the electrolytic parameters. We determine four electrolytic parameters : 1) Id=3 _<mu>A, Td=30 _<sX> 2) Id=5 _<mu>A, Td=30_s 3) Id=7 _<mu>A, Td=30_s 4) Id=10 _<mu>A, Td=50_s. We investigated the reproducibility of measured values of local blood flow in masseter muscle tissue both at rest and in a rest-clench-rest sequence. The tests were conducted on two days, more than thirty days apart, with the following results :
At rest position, the variation in measured blood flow in the course of one day is minimal, and the variation between the first and second days is large, except parameter4. During rest-clench-rest sequence, the variation in the measured values observed in one day and that between the first and second days is larger than the results measured only in the rest position, with the exception of parameter4.
Based on these data, we concluded that when applying this electrolytic method, we must maintain the positional relationship between the inserted electrode and surrounding tissue. We also surmised that clenching caused changes to occur between them, and the degree of disparity became greater. In parameter4, more hydrogen gas was generated than parameters1, 2or3, and changes in the position of electrode in the tissue had no effect on measurement values. In parameter4, measurement blood flow after clench was larger than that measured in the rest before clench. However, the amount of increase was little.
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