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Psychophysiological study of the mechanism of REM-NREM rhythm.

Research Project

Project/Area Number 01510093
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Psychology
Research InstitutionTokyo Metropolitan Institute for Neurosciences

Principal Investigator

MIYASITA Akio  Dept. of Psychology, Tokyo Metropolitan Inst. for Neurosciences, Associate Researcher., 心理学研究部門, 主任研究員 (70100146)

Project Period (FY) 1989 – 1991
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1991: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1990: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1989: ¥900,000 (Direct Cost: ¥900,000)
Keywordshuman sleep / REM sleep / interruption method / sleep onset REM period / Body temperature rhythm / hallucination / sleep paralysis / Modified reset hypothesis / リセット仮説 / BRAC仮説 / sleepーdependent仮説 / Sleepーdependent仮説
Research Abstract

We have investigated the factors influencing the appearance rate of sleep onset REN period(SOREMP), which is elicited by a sleep interruption method. in 1991, we focused on the SOREMP and exalued the subjective experiences and the physiological background during SOREMP. This abstract describes the results conducted in 1991.
Subjects had their sleep interrupted for 60 minutes by forced awakening when 40 minutes of NREM sleep had elapsed in the 1st or 3rd sleep cycle. This schedule produced sleep onset REM period(SOREMP)at a high rate of 71.9%. We succeeded in eliciting six episodes of isolated sleep paralysis(ISP). All episodes of ISP except one occurred from SOREMP, indicating a close correlation between ISP and SOREMP. We recorded verbal reports and the polysoinograi(PSG)during the ISP. All the subjects with ISP experienced Inability to move and were aware of lying in the laboratory. All but one reported hallucinations and unpleasant emotions. PSG during ISP were characterized by a W/REN dissociated state, i. e, abundant alpha EEG and persistence of muscle atonia. ISP differs from other dissociated states as lucid dreaming, nocturnal panic attacks, and REM sleep behavior disorders.
We also Investigated the effects of the Interruption on rectal temperature(RT). Following interruption, RT decreased drastically as well as after the first sleep onset. It remianed lower, for two hours, than the corresponding baseline night. Consequently, the value of the curve-trough lowered and the position of the trough advanced. In interrupted nights, the RT fall after interruption was not accompanied by any increase In slow wave sleep. So we suggest no direct relationship between RT fall and amount of SWS. We compared RT patterns between nights with SOREMP and without SOREMP. In SOREMP nights, RT tended to be lower at the second sleep onset than SOREMP nights. There may be physiological causes for this SOREMP appearance.

Report

(4 results)
  • 1991 Annual Research Report   Final Research Report Summary
  • 1990 Annual Research Report
  • 1989 Annual Research Report
  • Research Products

    (23 results)

All Other

All Publications (23 results)

  • [Publications] 宮下 彰夫: "Appearance rate of sleep onset REM period and preーawakening NREM durtion" Sleep.Res.18. 141 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 宮下 彰夫: "人間の生活と睡眠." 精神科看護. 35. 2-7 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 福田 一彦: "若年健康者にみられる金縛り現象" 臨床脳波. 34. 1-4 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 宮下 彰夫: "Pattern,trogh,and amplitude of rectal temperature during sleep in healthy subjects." Jap.J.Psychiat.Neurol.45. 149 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 竹内 朋香: "Sleep habit and its evaluation in normal population with isolated sleep paralysis." Jap.J.Psychiat.Neurol.45. 945 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 佐々木 由香: "The timing of nocturnal sleep interruption and pattern change of rectal temperature." Jap.J.Psychiat.Neurol.45. 949 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 宮下 彰夫: "眠りと夢と脳.In堀忠雄・斉藤勇(編)脳と心のトピックス" 誠信書房, 21 (1989)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 宮下 彰夫: "自律神経系のリズムIn千葉喜彦・高橋清久(編)時間生物学ハンドブック" 朝倉書店, 9 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Miyasita, A., Fukuda, K., and Inugami, M.: "Effects of sleep interruption on REM-NREM cycle in nocturnal human sleep." Electroenceph. clin. Neurophysiol.73(8). 107-116 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Miyasita, A., Fukuda, K., Inugami, M. and Ishihara, K.: "Appearance rate of sleep onset REM period and pre-awakening NREM duration." Sleep Res.18. 141 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Takeuchi, T., Sasaki, Y., Miyasita, A., Inugami, M. and Fukuda, K.: "Comparison of the sleep paralysis elicited by interruption schedule with dreaming." Jap. J. Psychiat. Neurol.44(4). 846 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Sasaki, Y., Takeuchi, T., Miyasita, A., Inugami, M. Fukuda, K. and Ishihara, K.: "Effects of short interval of sleep interruption on rectal temperature." Jap. J. Psychiat. Neurol.44(4). 840-841 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Miyasita, A., Inugami, M., Ishihara, K., Fukuda, K. Sasaki, Y., and Takeuchi, T.: "Pattern, trough, and amplitude of rectal temperature during sleep in healthy subjecs." Jap. J. Psychiat. Neurol.45(1). 149 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Takeuchi, T., Sasaki, Y., Miyasita, A., Inugami, M. and Fukuda, K.: "Sleep habit and its evaluation in normal population with isolated sleep paralysis." Jap. J. Psychiat. Neurol.45(4). 954 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Sasaki, Y., Takeuchi, T., Miyasita, A., Inugami, M. Fukuda, K. and Ishihara, K.: "The timing of nocturnal sleep interruption and pattern change of rectal temperature." Jap. J. Psychiat. Neurol.45(4). 949 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 宮下 彰夫: "Appearance rate of sleep Onset REM period and preーawakening NREM duration" Sleep.Res.18. 141 (1989)

    • Related Report
      1991 Annual Research Report
  • [Publications] 宮下 彰夫: "人間の生活と睡眠" 精神科看護. 35. 2-7 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 福田 一彦: "若年健康者にみられる金縛り現象" 臨床脳波. 34. 1-4 (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] 宮下 彰夫: "Pattern,trough,and amplitude of rectal temperature during sleep in healthy subjects" Jap.J,Psychiat.Neurol.45. 149 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 竹内 朋香: "Sleep habit and its evaluation in normal population With isolated sleep paralysis." Jap.J.Psychiat.Neurol.45. 945 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 佐々木 由香: "The timing of nocturnal sleep interruption and pattern change of rectal temperature." Jap.J.Psychiat.Neurol.45. 949 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 宮下 彰夫: "眼りと夢と脳.In堀 忠雄・斉藤 勇(編)脳と心のトピックス" 誠信書房, 21 (1989)

    • Related Report
      1991 Annual Research Report
  • [Publications] 宮下 彰夫: "自津神経のリズムIn千葉 喜彦・高橋 清久(編)時間生物学ハンドブック" 朝倉書店, 9 (1991)

    • Related Report
      1991 Annual Research Report

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Published: 1989-04-01   Modified: 2016-04-21  

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