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Correlation between Transfer Rata and Atherogenic Site at the Separated Region Around Bifurcation Point

Research Project

Project/Area Number 01550158
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Fluid engineering
Research InstitutionShibaura Institute of Technology

Principal Investigator

YAMAGUCHI Ryuhei  Shibaura Institute of Technology Department of Mechanical Engineering Associate Professor, 工学部 (90103936)

Co-Investigator(Kenkyū-buntansha) TANAKA Kazuhiro  Kyusyu Institute of Technology Department of Mechanical System Engineering Assoc, 工学部, 助教授 (80171742)
Project Period (FY) 1989 – 1990
Project Status Completed (Fiscal Year 1990)
Budget Amount *help
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1990: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1989: ¥1,500,000 (Direct Cost: ¥1,500,000)
KeywordsFluid Mechanics / Bifurcating Vessel / Wall Shear Stress / Electrochemical Method / Atherosclerosis / Abdominal Aorta / Physiology / 分岐流れ
Research Abstract

It is well known that the variation of wall shear stress, i. e. momentum transfer rate, is closely associated with the disease of vascular wall such as atherosclerosis. In general, the distribution of wall shear stress is affected by the vessel geometric shape.
In the present study, the distribution of wall shear stress in the 45-deg bifurcation model during steady flow has been measured by the electrochemical method which is based on a diffusion-controlled reaction of ferricyanide ion to ferrocyanide ion at the platinum electrode (diameter=0.5mm). Approximately 200 test electrodes were embedded in vessel wall. The model made of plexiglas consisted of the parent vessel (D_0=24mm) and the daughter vessel (D_1=14mm). The curvature of outer wall in daughter vessel and flow divider (apex) was R_D=3.5D_0 and R_C=D_0/8, respectively. This bifurcation models the arterial site from abdominal aorta to inferior mesenteric artery. The experiment has been carried out in the range of Reynolds number … More 500, 800 and 1200, and in both condition of steady and pulsating flow. In pulsating flow, the non-dimensional frequency is (D_0/2) <square root>omega/nu=6. The ratio of flow rate in daughter vessel to total flow rate in upstream parent vessel is about 0.25 which corresponds to the ratio of cross sectional area in each downstream vessel. The flow pattern was visualized by a dye injection.
In steady flow, the flow through this bifurcation was characterized at the outer wall of daughter vessel. at outer wall of parent vessel and near the flow divider. At the outer wall of daughter vessel, the wall shear stress changes periodically. This periodical variation relates to double helical flow which flows into daughter vessel from the upstream parent vessel near vessel wall. At this wall the flow does not separate. At the outer wall of parent vessel, the separation region occurs near bifurcation point, and therefore the wall shear stress would be negative there. At the flow divider, after the wall shear stress becomes maximum at apex, it decreases and asymptotically approaches the wall shear stress of downstream Poiseuille flow
In pulsating flow, the variation of wall shear stress at maximum flow rate is greater than that corresponding steady flow, and vise versa. The time variation at each wall site is remarkably near the bifurcation point. Less

Report

(3 results)
  • 1990 Annual Research Report   Final Research Report Summary
  • 1989 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] 山口 隆平,山口 隆美,矢野 徳康: "動脈分岐モデルの壁面せん断応力分布" 日本バイオレオロジ-学会年会抄録集. 4. 35 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] R.Yamaguchi T.Yamaguchi: "Wall Shear Stress in Bifurcation Model of Abdominal Aorta during Steady Flow" First World COngress of Biomechanics. 1. 117 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 山口 隆平,矢野 徳康,山口 隆平: "非対称分岐部回りの流れと壁面せん断応力分布" 日本機械学会論文集 投稿中(90ー1383).

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 矢野 徳康,山口 隆平,山口 隆美: "非対称分岐部回りの流れと壁面せん断応力分布" 日本機械学会 第68期通常総会講演会論文集. (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 山口 隆平,矢野 徳康: "脈動流中における分岐支管外壁上の移動速度分布" 日本機械学会論文集.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Ryuhei Yamaguchi: "Shear Stress in Abdominal Aorta Model during Steady Flow" Proc. Japanese Society of Biorheology. vol. 13. 35 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Ryuhei Yamaguchi: "Wall Shear Stress in Bifurcation Model of Abdominal Aorta during Steady FLow" First World Congress of Biomechanics. vol. 1. 117 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Ryuhei Yamaguchi: "Flow Pattern and Wall shear Stress through Unsymmetrical Branch in steady FLow" Proc. 68th JSME Spring Annual Meeting. 910-17. (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] Ryuhei Yamaguchi: "Flow Pattern and Wall shear Stress through Unsymmetrical Branch in Steady FLow" Trans. JSME.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1990 Final Research Report Summary
  • [Publications] 山口 隆平,山口 隆美,矢野 徳康: "動脈分岐モデルの壁面せん断応力分布" 日本バイオレオロジ-学会年会抄録集. 4. -35 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] R.Yamaguchi,T.Yamaguchi: "Wall Shear Stress in Bifurcation Model of Abdominal Aorta during Steady Flow" First World Congress of Biomechanics. 1. -117 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 山口 隆平,矢野 徳康,山口 隆美: "非対称分岐部回りの流れと壁面せん断応力分布" 日本機械学会論文集投稿中(90ー1383).

    • Related Report
      1990 Annual Research Report
  • [Publications] 矢野 徳康,山口 隆平,山口 隆美: "非対称分岐部回りの流れと壁面せん断応力分布" 日本機械学会第68期通常総会講演会論文集. (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 山口 隆平,矢野 徳康: "脈動流中における分岐支管外壁上の移動速度分布" 日本機械学会論文集. (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 山口隆平,矢野徳康,山口隆美: "腹部大動脈分岐部モデルにおける壁面せん断応力分布" 第13回日本バイオレオロジ-学会 1990.6/21〜6/23,奈良.

    • Related Report
      1989 Annual Research Report
  • [Publications] 山口隆平,山口隆美: "Wall Shear Stress in Bifurcation Model of Abdominal aovta during Steady Flow" First World Congress of Biomechanics 1990.8/30〜9/4,in San Diego.

    • Related Report
      1989 Annual Research Report

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Published: 1989-04-01   Modified: 2016-04-21  

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