Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 1990: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1989: ¥1,300,000 (Direct Cost: ¥1,300,000)
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Research Abstract |
1. Distribution of staphylococal Species on Various Animal Skins 1) Staphylococci were detected in 29 (100%) of 29 pigs, 3 (30%) of 10 horses, 25 (59.5%) of 42 cattle, 2 (40%) of 5 goats, 46 (90.2%) of 51 quails, 30 (85.7%) of 35 chickens, 13 (59.1%) of 22 mice, 17 (81%) of 21 rats, and 18 (52.9%) of 34 humans. 2) The predominant staphylococci found on swine skin were S. xylosus and S. saprophyticus. 3) The predominant staphylococci found on cattle skin were S. xylosus, S. sciuri, S. lentus and S. cohnii. 4) The predominant staphylococci found on quail skin were S. cohnii and S. xylosus. 5) The predominant staphylococci found on chicken skin were S. hyicus, S. aureus and S. xylosus. 6) The predominant staphylococci found on mouse and rat skins were S. xylosus. 7) The predominant staphylococci found on human skin were S. hominis and S. epidermidis. 8) Novobiocin-resistant species, S. xylosus was isolated from a wide variety of animal species. 10) The staphylococcal skin flora of anaimls differed markedly from that associated with man. 2. Adherence of staphylococci to Epidermal Cells of Mice Fourteen Staphylococcus species were examined for their adherence to epidermal cells of mice. Among the 14 species, S. sciuri ATCC 29062 strain adhered well to the cells. Interestingly, S. sciuri is a major member of the noramal flora found on the skin of rodents, including laboratory mice. There may possibly be factors other than protein A responsible for the adherence of this species to mouse epidermal cells.
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