| Project/Area Number |
01570495
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Saga Medical School |
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Principal Investigator |
MATSUO Shuzo Saga Med. School Dep. of Int. Med. professor, 医学部, 教授 (60039823)
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| Co-Investigator(Kenkyū-buntansha) |
TOKUSHIMA Takashi Saga Med. School Dep. of Int. Med. assistant, 医学部, 助手 (70207546)
EGUCHI Yoshiki Saga Med. School Dep. of Int. Med. assistant, 医学部, 助手 (70193993)
TSURUTA Mitsuhiro Saga Med. School Dep. of Int. Med. assistant, 医学部, 助手 (50155446)
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| Project Period (FY) |
1989 – 1990
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| Project Status |
Completed (Fiscal Year 1991)
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| Budget Amount *help |
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1990: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1989: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Coronary blood flow / Doppler flowment cathether / Ischemic heart disease / Coronary flow reserve / 冠動脈血流 / カテ先ドプラ血流計 / 運動負荷 |
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| Research Abstract |
Phasic coronary flow velocity was recorded in 20 patients by using Doppler flowmeter catheter. Coronary flow velocity was measured in 15 cases at left anterior descending artery (LAD), 6 cases at right coronary artery (RCA) and 3 cases at left circumflex artery (CX).
TVIs, TVId, TVIt, %DF, Vs, Vd, Vm and S/D were measured in the group -of LAD stenosis (group L) and groupof normal LAD (group C). Those values were not significantly different between group L and C at rest. Under the intravenous infusion of nitroglycerin, TVIt and Vm were increased in group C. However, those were not increased in group L, indicating decreased coronary flow reserve. Incased coronary flow velocity was also recorded in the case of group L after PTCA.
The measurement of coronary flow velocity by using Doppler flowmeter catheter could be useful ori the study of coronary dynamics, especially patients with ischemic heart disease.
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