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A Study of Hemodynamics on Exercise Stress Test in Children of High Risk Group for Hypertension and High Risk Group for Arteriosolerosis

Research Project

Project/Area Number 01570531
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Pediatrics
Research InstitutionShimane Medical University

Principal Investigator

HANEDA Noriyuki  Shimane Medical University, Department of Pediatrics, Assistant Professor, 医学部, 講師 (20127525)

Co-Investigator(Kenkyū-buntansha) HARADA Yurika  Shimane Medical University, Department of Pediatrics, Member of Clinical Researc, 医学部, 医員
KISHIDA Kenji  Shimane Medical University, Department of Pediatrics, Assistant, 医学部, 助手 (90186213)
岩谷 一  島根医科大学, 医学部, 助手 (40213300)
Project Period (FY) 1989 – 1991
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 1991: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1990: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1989: ¥800,000 (Direct Cost: ¥800,000)
Keywordsblood pressure / serum cholesterol / tracking / exercise / children / left ventricular diastolic function / トラッキング / 小児 / 心機能
Research Abstract

It is well documented that there is the tracking phenomenon, that is, children showing high blood pressure among the children of the same age from childhood have high blood pressure with the advance of age and likewise those showing low blood pressure have low blood pressure eventually. The same goes for serum totalcholesterol Where, therefore, high blood pressure or high serum cholesterol levels in childfood, the probability is high that they shift to hypertension or hypercholesterolemia in the future.
It was pointed out in the early year of our study that a decline in the left ventricular diastolic function at rest was shown by echocardiographic measurement about children considered at high risk of these adiilt diseases. Last year oercise stress test with an ergoineter was done for 6 to 15-year old children belonging to that group and done for normal children of the same age as the control, and the left ventricular diastolic function on exercise loading analyzed by echocardiography wa … More s studied. This year Lhe study oil the left veiitricular diastolic function by exercise stress test with 9 to 18-year old children was continued as in last year. Exercise loading with an ergometer was done for 3 I)oys with high blood pressure, 3 boys with high serum cholesterol levels and 5 normal boys as the control. And the cardiac function was analyzed by echocardiography. As a result, an increase in the heart rate and blood pressure was noted early in the high blood pressure group as compared with other groups. An increase in the contraction of the left ventricle against exercise loading was sufficient and the reserved capacity was kept well. There were cases in which a decline in the left ventricular diastolic function was made clear by exercise stress test. When viewed on the whole with the cases of this year and cases of last year put together, a decline in the left ventricular diastolic function including prolongation of the corrected left ventricular isovolumic relaxation time and a decrease of the peak velosity of increase in the left ventricular dimnsion was noted even at rest and became prominent with exercise stress test. The reproducibility tend to be higher with exercise stress test on the high serum cholesterol level group than on the high blood pressure group.
The results of our study suggest the importance of observations on the clinical course with attention paid to the latent decline in the cardiac function in children considered belonging to a high risk group for hypertension or arteriosclerosis. Less

Report

(4 results)
  • 1991 Annual Research Report   Final Research Report Summary
  • 1990 Annual Research Report
  • 1989 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] Koji Watanabe: "Relation between blood pressure,left ventricular mass and pulsed doppler parameters in healthy school children." Acta Paediatrica Japonica. 32. 275-281 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yurika Hayashi: "Changes of left ventricular isovolumic relaxation time with growth in children." Acta Paediatrica Japonica. 32. 282-290 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yurika Harada: "Left ventricular diastolic function of children in high blood pressure tracking group." Acta Paediatrica Japonica. 32. 530-539 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Koji Watanabe: "Japan:Perspectives in school health." Journal of school health. 60. 330-336 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 原田 由利香: "血圧高値持続学童及び血清コレステロ-ル高値持続学童に対する運動負荷心エコ-の検討" 若年者心疾患対策協議会誌. 19. 44-68 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Toshikazu Nishio, Katsutoshi Abe, Masakazu Saito, Noriyuki Haneda, Koji Watanabe, Susumu Okahara & Chuzo Mori: "Percentile Value of blood pressure in childhood, and anthropometric measurements in normotensive and hypertensive children. The Shimane Heart Study" Shimane J. Med. Sci. 5. 144-150 (1981)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Chuzo Mori, Noriyuki Haneda, Kenji Kishida, Yurika Harada, Shiro Seto, Koji Watanabe & Toshikazu Nishino.: "Tracking of blood pressure and cholesterol in children - The Shimane Heart Study -" Presented at Interdisciplinary Symposium on Gene,. Nutrition and Health, Kobe. (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yurika Harada, Chuzu Mori, Koji Watanabe, Kenji Kishida, Noriyuki Haneda, Hajime Iwatani, & Toshikazu Nishio: "Left ventricular diastolic function of children in high blood pressure tracking group" Acta Padiatr Jpn. 32. 530-539 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yurika Harada, Noriyuki Haneda & Chuzo Mori: "Echocardiographic findings on exercise stress test in children of high blood pressure tracking group and high cholesterol tracking group." Jakunenshasinsikkantaisakukyogikaishi. 19. 44-68 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yurika Hayashi: "Changes of Left Ventricular Isovolumic Relaxation Time with Growth in Children" Chuzo Mori Acta Bediatrica Japonica. 32. 282-290 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] Yurika Harada: "Left Ventricular Diastolic Function of Children in High Blood Pressure Tracking Group" Acta Paediatrica Japonica. 32. 530-539 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] Koji Watanabe: "Relation between blood pressure,left ventricular mass and pulsed doppler purameters in healthy school children" Acta Paeditrica Japonica. 32. 275-281 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] Yurika Hayashi: "Changes of Left Ventricular Isovolumic Relaxation Time with Growth in Children" Acta Paediatrica Japonica. 32. 282-290 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Yurika Harada: "Left Ventricular Diastolic Function of Children in High Blood Pressure Tracking Group" Acta Paediatrica Japonica. 32. 530-539 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Yurika Hayashi,et al: "Changes of Left Ventricular Isovolumic Relaxation Time with Growth in Children." Acta Paediatrica Japonica. 32. (1990)

    • Related Report
      1989 Annual Research Report
  • [Publications] Yurika Hayashi,et al: "Left Ventricular Diastolic Function of Children in High Blood Pressure Tracking Group"

    • Related Report
      1989 Annual Research Report

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Published: 1989-04-01   Modified: 2016-04-21  

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