| Project/Area Number |
02041066
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Field Research |
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| Research Institution | Kyushu University |
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Principal Investigator |
KAWASHIMA Kenjiro Professor, School of Health Sciences, Kyushu University, Fukuoka, 医療技術短期大学部, 教授 (30038690)
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| Co-Investigator(Kenkyū-buntansha) |
KETUDAT P. スリスカリンウイロート大学, 理学部, 助教授
THAITHONG Sodsri Professor, Faculty of Science, Chulalongkorn University, Bangkok, 理学部, 教授
SINGH M.S. ノースイースタン医科大学, 教授
SINGH T.S. ノースイースタン医科大学, 助教授
姜 華 北京医科大学, 人民医院, 助手
賀 聨印 北京医科大学, 人民医院, 教授
SUGIYAMA Hiromu Senior researcher, National Institute of Health, Tokyo, 主任研究官 (00145822)
SHIBAHARA Toshiyuki Associate Professor, School of Medicine, Tottori University, Yonago, Tottori, 医学部, 助教授 (70116937)
AGATSUMA Takeshi Research Associate, Kochi Medical School, Nankoku, Kochi, 医学部, 助手 (40117031)
HABE Shigehisa Research Associate, School of Medicine, Fukuoka University, Fukuoka, 医学部, 助手 (70037430)
TERASAKI Kunio Professor, St. Mary's Junior College, Kurume, 教授 (80078675)
SINGH M. Samarendra Professor, North Eastern Regional Medical College, Imphal
SINGH T. Shantikumar Associate Professor, North Eastern Regional Medical College, Imphal
JIANG Hua Research Associate, People's Hospital, Beijing Medical University, Beijing
HO Lian-Yin Professor, People's Hospital, Beijing Medical University, Beijing
KETUDAT Punsin Associate Professor, Faculty of Science, Srinakharinwirot University, Bangkok
賀 聯印 北京医科大学, 人民医院, 教授
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| Project Period (FY) |
1990 – 1991
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| Project Status |
Completed (Fiscal Year 1991)
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| Budget Amount *help |
¥8,000,000 (Direct Cost: ¥8,000,000)
Fiscal Year 1991: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 1990: ¥5,000,000 (Direct Cost: ¥5,000,000)
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| Keywords | Paragonimus / Taxonomy / Genetic variation / Host specificity / Karyotype analysis / Isozyme analysis / China / India & Thailand / Bionomics / Karyotype analysis / India / Thailand / Speciation |
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| Research Abstract |
The present study is to deduce (1) the origin of the triploids of Paragonimus westermani of Japan and (2) what P. westermani is which was described by Kerbert in 1878. More than 5, 000. Paragonimus metacercariae were isolated from 1, 873 crayfishes (Cambaroides dauricus, C. shrenkii) collected in 3 provinces of north-eastern China in 1990. They were identified as P. westermani based on their morphology as well as that of the adults. The flukes, especially from Liaoning Province were proved to be diploid, triploid and tetraploid types. The triploid fluke from China was almost the same as Japanese one not only in host-specificity but also in electrophoretic patterns. In the diploid fluke, Chinese populations were polymorphic in electrophoretic patterns, while Japanese ones were monomorphic. The specific alleles of Japanese triploid were found, with high frequency, in the diploid populations in China. Therefore, a certain diploid population of this fluke in north-eastern China seems to be
… More
related to the ancestor of Japanese triploid in terms of the gene introgression. Thirty-six Paragonimus metacercariae were isolated from 79 crabs (Potamiscus manipurensis) collected in Manipur, India, in 1990. They were provisionally classified into 2 groups. The morphology of the adult originating from P. westermani type metacercariae was in good agreement with the description of P. westermani by Vevers (1923), but not by Kerbert (1878). Eight hundred forty-three Paragonimus metacercariae were isolated from 570 crabs (the same as above) collected in Manipur, India, in 1991. They were provisionally classified into 4 groups. Seven hundred seventy-three Paragonimus metacercariae were isolated from 205 crabs (Phricotelphusa spp., Ranguna smalley) collected in southern Thailand, in 1991. They were classified into 2 groups. Further studies on Indian and Thai Paragonimus are now in progress. Epidemiological studies on human paragonimiasis as well as further biological studies on the flukes which are causative agents of this disease in India are highly important, because a great many of patients of paragonimiasis and multiple Paragonimus species have been found there. Less
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