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Collaborative Research of Artificial Gravity for Space Use.

Research Project

Project/Area Number 02044135
Research Category

Grant-in-Aid for international Scientific Research

Allocation TypeSingle-year Grants
SectionJoint Research
Research InstitutionNihon University

Principal Investigator

YAJIMA Kazuyoshi  Nihon University School of Medicine, 医学部, 教授 (40010029)

Co-Investigator(Kenkyū-buntansha) アナトリー グリゴリエフ  旧ソ連保健省医学生物学問題研究所, 所長
カール クライン  ドイツ航空宇宙研究所, 航空宇宙医学研究所, 所長
ジェームス ウォルフ  テキサス大学, 生命科学部, 教授
フランク サルツマン  NASA本部, 宇宙医学生物学部, 主任
IGARASHI Makoto  University Research Center, Nihon University, 総合科学研究所, 教授 (30231731)
ITO Masao  Nihon University School of Medicine, 医学部, 講師 (40059887)
MIYAMOTO Akira  Nihon University School of Medicine, 医学部, 助教授 (40150271)
KUROKAWA Kiyoshi  University of Tokyo, School of Medicine, 医学部, 教授 (30167390)
GRIGORIEV Anatoly I.  Institute for Biomedical Problems Ministry of Health of Russia
KLEIN Karl E.  Institute for Aerospace Medicine German Aerospace Research Establishment
WOLFE James W.  Life Science Division, University of Texas
SULZMAN Frank M.  Life Science Division, NASA Headquarters
グリゴリエフ アナトリー  旧ソ連保健省医学生物学研究所, 所長
クライン カール  ドイツ航空宇宙研究所, 航空宇宙医学研究所, 所長
ウォルフ ジェームス  テキサス大学, 生命科学部, 教授
サルツマン フランク  NASA本部, 宇宙医学生物学部, 主任
ウォルフ ジェームズ  テキサス大学, 生命科学部, 教授
Project Period (FY) 1990 – 1992
Project Status Completed (Fiscal Year 1992)
Budget Amount *help
¥14,500,000 (Direct Cost: ¥14,500,000)
Fiscal Year 1992: ¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 1991: ¥5,000,000 (Direct Cost: ¥5,000,000)
Fiscal Year 1990: ¥4,500,000 (Direct Cost: ¥4,500,000)
KeywordsArtificial gravity / Long time G-load / Vestibular dysfunction / Circulatory failure / Lowering of work capacity / A countermeasure on loss of Ca under microgravity / Short-arm human centrifuge / 人間の長時間Gz負荷 / 循環系の副作用 / 無重力のCa喪失の対策 / 遠心力負荷装置 / 人間の長時間G負荷 / 宇宙医学 / 作業パフォ-マンスへの影響 / 前庭神経系への影響 / 長時間G耐性
Research Abstract

1. Results of G-load experiments using a short-arm human centrifuge
Based on the artificial G-load experiments by a short-arm human centrifuge before the present research year, we found that the subjects suffered from motion sickness-like symptoms (which is usually seen as a vestibular dysfunction caused by Coriolis stimulation), when a centrifugal force is given in +z (head to heel) direction. Accordingly, in order to avoid the occurrence of vestibular symptoms, we eliminated various mechanical problems such as microvibration. Also, toreduce subject's psychological tension, we have given a very detailed explanation and also used a short-duration experience of centrifugal G-load. First, we acquired data from 5 healthy male subjects, 20-30 years old, by applying 1.2G for 40 minutes, 1.4G for 40 minutes on the following day and then 1.8G for 40 minutes on the next day.
Before and after G-load, we measured various human performances and also obtained a stabilogram which is a measurement of … More man's ability of standing postural maintenance. During the load, we recorded EKG, heart rate, respiratory curve, eye movement, pupillary condition, oxygen saturation, and blood pressure (every 1 minute). We continually observed subject's condition through the video camera system. The subject and experimentor could tele-communicate call the time.
As a next step, we tried to expose subjects to 2.0G for 40 minutes. Except for subject who could complete this load at his second trial, the load had to be stopped, for all subjects who complained an extreme unpleasantness or hardness and manifested objective symptoms such as low blood pressure. Thereafter, we decided to extend the exposure period for 60 minutes instead, and started from 1.4G. If the subject could complete a 1.4G load, the level went up to 1.7G. If he could not complete 1.7G, he had to go back to 1.4G again. Based on our data to present, we set the maximal level as 2.0G for 60 minutes and we did not use any higher or longer exposure. To data, 9 subjects completed 1.4G load for 60 minutes, but 4 could not ; 6 completed 1.7G for 60 minutes but 5 could not ; and 3 completed 2.0G for 60 minutes but 3 could not.
Subjects who failed to complete the G load showed various autonomic nervous system symptoms such as cold sweat, tachycardia, head heaviness etc., and they complained the condition as intolerable. Symptoms like low blood pressure, brain anemia etc. due to circulatory failure by an extreme G load, and heart rate reduction by vagotony were not found in this subject group. performance by subjects who could complete the scheduled G level load returned to the preexposure performance level within 2 hours.
2. Reports at the international meetings and international information exchange
Members of our research group and research collaborators have made multiple presentations in relation to the centrifugal G-load, at many international meetings and congresses ; in Nagoya, March, 1992 ; in Miami Beach, May, 1992 ; in Washington,D.C., August, 1992 ; in Hawaii, September, 1992 ; in Tokyo, October, 1992. Our new and unexpected findings on brain circulation during G-load have delivered a great impact to the related research community. Furthermore, life science and medical leaders in NASA organization have clearly recognized the importance of artificial G-load experiments, and intend to support an active exchange of information among the international research groups.
The Man-in-Space Symposium of the International Association of Astronautics will be held in Tokyo, April, 1993, under the chairmanship of the Principal Investigator. During this meeting, we scheduled to have a special session of "artificial gravity", as a summerization of our research works to data. During this unique and very first study session on "artificial gravity", out of a total of 9 papers, we will have 5 presentations from Japan (4 from our group), 3 from U.S.A. and 1 from Russia.
After the initiation of Clinton administration, the future of the space program does not look very bright, and some grim views exist among the global space community. Sometime ago, we have structured an international study forum of artificial gravity research. Unfortunately, the system is not functioning properly at this moment, basically due to somewhat inactive movement of NASA people. This exemplifies the real difficulty of international collaboration. Nonetheless, we are anxious to continue our artificial G load studies. Less

Report

(3 results)
  • 1992 Final Research Report Summary
  • 1991 Annual Research Report
  • 1990 Annual Research Report
  • Research Products

    (27 results)

All Other

All Publications (27 results)

  • [Publications] 吉本 智信,谷島 一嘉,他1名: "スペースラットの作製 --出産まで--" 第9回宇宙利用シンポジウム講演集. 9. 135-136 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 合野 俊昭,谷島 一嘉,宮本 晃,他3名: "個人間の脳循環反応の差 --宇宙飛行への適応性--" 第9回宇宙利用シンポジウム講演集. 9. 188-192 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 伊藤 雅夫,谷島 一嘉,他8名: "マウス卵子の受精と初期発生におよぼすG負荷の影響" 日本宇宙環境医学会雑誌. 30(1). (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岩崎 賢一,伊藤 雅夫,谷島 一嘉,他7名: "小型遠心機による人工重力負荷中の動脈血酸素飽和度の変化" 日本宇宙環境医学会雑誌. 30(1). (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 岩崎 賢一,宮本 晃,伊藤 雅夫,谷島 一嘉,他5名: "人工重力負荷中の動脈血酸素飽和度" 日本衛生学会誌. 48(1). 336 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K.YAJIMA,A.MIYAMOTO,M.ITO,et.al.: "Orthostatic intolerance in 6 degrees Head-Down Tilt and lower body negtive pressure loading." ACTA ASTRONAUTICA. 27. 115-121 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T.UENO,K.YAJIMA,et.al.: "Effect o lower body negative on cerebral circulation." Aviation Space and Environmental Medicine. (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 上野 俊昭,谷島 一嘉,他1名: "過重力の神経生理学的機能に及ぼす影響" 第6回日本宇宙生物科学会. (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 吉本 智信,谷島 一嘉,他1名: "重力負荷の脳循環に与える影響" 第6回日本宇宙生物科学会. (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T.UENO,A.MIYAMOTO,K.YAJIMA,et.al.: "Effect of LBNP on cerebral circylation" 63rd.Aunual Scientific Meeting of Aerospace Medical Association. A35 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 谷島 一嘉: "無重力とデミネラリゼーション" ファルマシア(日本目学会). 28(12). 1353-1355 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 谷島 一嘉: "ヘッドダウンベッドレストの生理" 臨床スポーツ医学(文光堂). 10. 5-11 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] S. Yoshimoto, K. Yajima, et.al.: "The making of space rat --from fertilization to birth--" Proceeding of the ninth space utilization symposium.9. 135-136 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T. Ueno, K. Yajima, A. Miyamoto, et.al: "Cerebral circulation against the gravitational stress --selection of candidates for astronauts--" Proceeding of the ninth space utilization symposium.9. 188-192 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M. Ito, K. Yajima, et.al.: "Effect of Chronic centrifugation on in vitro fertilization and early development in Mice." Japanese journal of aerospace and environmental medicine.30(1). (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K. Iwasaki, M. Ito, K. Yajima, et.al.: "Arterial oxygen saturation during +Gz acceleration by short-radius centrifuge." Japanese Journal of aerospace and environmental medicine.30(1). (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K. Iwasaki, A. Miyamoto, M. Ito, K. Yajima, et.al.: "Arterial oxygen saturation during +Gz acceleration." Japanese journal of Hygiene.48(1). 336 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K. Yajima, A. Miyamoto, M. Ito, et.al.: "Orthostatic intolerance in 6 degrees Head-Down Tilt and lower body negative pressure loading." Acta Astronautica.27. 115-121 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T. Ueno, K. Yajima, et.al.: "Effect to lower body negative pressure on cerebral circulation." Aviation Space and Environmental Medicine.(1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T. Ueno, K. Yajima, et.al: "Effect of hyper-G on neuro-physiological function." Biological Science in Space Symposium.(1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] S. Yoshimoto, K. Yajima, et.al.: "Effect of artificial G-load on cerebral circulation." Biological Science in Space Symposium.(1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] T. Ueno, A.Miyamoto, K. Yajima, et.al.: "Effect of LBNP on cerebral circulation." 63rd. Annual Scientific Meeting of Aerospace Medical Association.A35 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K. Yajima.: "Agravity and demineralization." FARUMASHIA (The Pharmaceutical Society of Japan). 28(12). 1353-1355 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K. Yajima: "Physiology of head-down bedrest." The journal of clinical sports medicine. (Bunkodo). 10. 5-11 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 谷島 一嘉: "人工重力研究用小型遠心力発生装置によるGの長時間負荷における人体の影響" 第8回宇宙利用シンポジウム講演集. 8. 234-238 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 谷島 一嘉,宮本 晃,五十嵐 眞,伊藤 雅夫: "Gの長時間負荷における人体の影響" 日本宇宙環境医学会雑誌. 37. 33 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 伊藤 雅夫,谷島 一嘉: "G負荷に条件下におけるマウスの受精と初期発生" 日本宇宙環境医学会雑誌. 37. 34 (1991)

    • Related Report
      1991 Annual Research Report

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Published: 1990-04-01   Modified: 2016-04-21  

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