Study on Gas Exchange in Respiration System
| Project/Area Number |
02452117
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fluid engineering
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| Research Institution | Research Center for Advanced Science & Technology, University of Tokyo |
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Principal Investigator |
TANIDA Yoshimichi Univ. of Tokyo, RCAST, Professor, 先端科学技術研究センター, 教授 (50013628)
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| Co-Investigator(Kenkyū-buntansha) |
YUMINO Takashi Tokai Univ. Engg. Fuculty, Lecturer, 工学部, 講師 (70056084)
NAGASHIMA Toshio Univ. of Tokyo, Engg. Fuculty, Prof., 工学部, 教授 (70114593)
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| Project Period (FY) |
1990 – 1991
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| Project Status |
Completed (Fiscal Year 1991)
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| Budget Amount *help |
¥4,100,000 (Direct Cost: ¥4,100,000)
Fiscal Year 1991: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1990: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | Respiration / Pulsating Flow / Gas Exchange / Branching Airway |
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| Research Abstract |
Experimental and numerical studies were carried out on flow and gas exchange in respiratory system. The results obtained are as follows.
(1) FLOW THROUGH THE NOSE : Using the oscillating flow channel with a intake of nose model prepared for the present purpose. the inspiratory and expiratory flows were visualized by smoke-wire method and tobacco smoke method. At high frequency, the fluid near the channel wall oscillates with some phase lag behind the core fluid and the steady streaming was observed around the nose. Further, the details of the oscillating flow is now being measured by the hot-wire anemometer and also the CO_2 diffusion in the oscillating air flow is being analyzed by using newly developed gas analyzer.
(2) FLOW AND GAS DIFFUSION IN A BRANCHING AIRWAY : Numerical study was carried out on the flow and gas diffusion in a 2D branching airway by solving the Navier-Stokes equation and diffusion equation by the FEM method. It was shown that the steady streaming becomes stronger for larger Reynolds number and lower Wormersley number and the gas diffusion is promoted in proportion to the strength of streaming.
(3) GAS EXCHANGE IN THE LUNG : Gas exchange in the respiratory network was studied by using newly proposed flow model in branching airways. The results obtained are in good agreement with the physiological data. It was predicted that in high-frequency ventilation the pendelluft effect can bring about the gas exchange comparable to that of ordinary respiration.
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Report
(3 results)
Research Products
(7 results)
