| Project/Area Number |
02454208
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
公衆衛生学
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| Research Institution | HOKKAIDO UNIVERSITY |
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Principal Investigator |
KONDO Kiyotaro HOKKAIDO UNIVERSITY,SCHOOL OF MEDICINE,PROFESSOR, 医学部, 教授 (80018366)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUSHIMA Tatsuaki AIZEN HOSPITAL,DEVISION OF INSPECTION,DIRECTOR, 臨床検査部, 部長
SHIDO Koichi HOKKAIDO UNIVERSITY,SCHOOL OF MEDICINE,INSTRUCTOR, 医学部, 助手 (20206098)
NIINO Minehisa HOKKAIDO UNIVERSITY,SCHOOL OF MEDICINE,INSTRUCTOR, 医学部, 助手 (80180561)
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| Project Period (FY) |
1990 – 1992
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| Project Status |
Completed (Fiscal Year 1992)
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| Budget Amount *help |
¥4,800,000 (Direct Cost: ¥4,800,000)
Fiscal Year 1992: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1991: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1990: ¥2,800,000 (Direct Cost: ¥2,800,000)
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| Keywords | SENILE DEMENTIAS / PRIMARY PREVENTION / BRAIN ACTIVATION THERAPY / ADL SCALES / REHABILITATION / 血管性痴呆 / 2次予防 / 介入疫学 / 危険要因 / 脳循環 / 介入 / 予防 / 脳活性化訓練 |
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| Research Abstract |
SIGNIFICANCE OF PRIMARY/SECONDARY/TERTIARY PREVENTION OF SENILE DEMENTIAS IS IMMENSE.IN OUR STUDY,RISK FACTORS IN ALZHEIMER'S DISEASE (AD) AND VASCULAR DEMENTIA (VD), MOSTLY INVOLVING MULTIINFARCT DEMENTIA AS WELL AS BINSWANGER DISEASE,WERE DETECTED AND ATTEMPT WAS MADE TO EVALUATE EFFECTS OF "BRAIN ACTIVATION THERAPY" IN DAY CARE FOR EARLY CASES OF AD AND VD.OF 135 FACTORS EVALUATED,WE DESCRIBED THAT
l) PRIOR TO AD AND VD,THE INDIVIDUALS WERE INACTIVE PSYCHOSOCIALLY,
2) PRIOR TO AD AND VD,THE INDIVIDUALS WERE INACTIVE PHYSICALLY,
3) ONLY VD WAS ASSOCIATED WITH VASCULAR RISK FACTORS INCLUDING HYPERTENSIONS,DIABETES,HYPERLIPIDEMIAS,ETC,
4) AD WAS ASSOCIATED WITH HEAD INJURY.
IN VIEW OF THESE RESULTS,WE PRODUCED A PREVENTIVE PROGRAMME IN DAY CARE.IN 34 CASES AND 20 CASES OF AD AND VD,THE INTERVENTION MADE FOR FIVE YEARS REVEALED THAT
1) ADL SCALES WERE IMPROVED IN AD AND VD,
2) MENTAL ABILITY SCALES WERE SIGNIFICANTLY IMPROVED IN VD BUT NOT IN AD,
3) LIFE WAS PROLONGED IN VD,
4) BENEFICIAL FACTORS WERE INTERVENTIONS,ACTIVATIONS IN HOME AND FAMILY SUPPORT.
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