| Project/Area Number |
02557052
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| Research Category |
Grant-in-Aid for Developmental Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
CHINZEI Tsuneo Research Associate, Research Center for Advanced Science and Technology, The University of Tokyo, 先端科学技術研究センター, 助手 (20197643)
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| Co-Investigator(Kenkyū-buntansha) |
FUJIMASA Iwao Professor, Research Center for Advanced Science and Technology, The University o, 先端科学技術研究センター, 教授 (30010028)
MABUCHI Kunihiko Associate professor, Research Center for Advanced Science and Technology, The Un, 先端科学技術研究センター, 助教授 (50192349)
ABE Yusuke Research Associate, Faculty of Medicine, The University of Tokyo, 医学部, 助手 (90193010)
IMACHI Kou Associate Professor, Faculty of medicine, The University of Tokyo, 医学部, 助教授 (10010076)
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| Project Period (FY) |
1990 – 1992
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| Project Status |
Completed (Fiscal Year 1992)
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| Budget Amount *help |
¥16,400,000 (Direct Cost: ¥16,400,000)
Fiscal Year 1992: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1991: ¥6,100,000 (Direct Cost: ¥6,100,000)
Fiscal Year 1990: ¥7,800,000 (Direct Cost: ¥7,800,000)
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| Keywords | Artificial Heart / Driving System / Liquefied Gas / Closed Circuit / 空気圧駆動 / 模擬循環回路 / 左心バイパス |
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| Research Abstract |
As driving mechanism of artificial heart, pneumatic, hydraulic and mechanical drivers are employed. Pneumatic driving mechanism has the advantage that the blood pump shape can be determined freely. However, this mechanism has disadvantage that driving apparatus is larger than other mechanism. To reduce the size of pneumatic drivers, we develop a new driving method with closed circuit of liquefied gas as the driving mediator. The principle of this method was that a single compressor produced low and high pressure with liquefied gas. The high pressure was maintained in a small reservoir with liquid-gas phase equilibrium. The high and low pressure were applied to sac type artificial heart, alternately.
According to this driving principle, we developed two type of liquefied gad driving circuit. In the first type, we consisted the driving apparatus as sequential circuit:compressor, condenser, evaporator, valves and blood pump. In this model, the apparatus can drive an blood pump at the flow of 3 to 4L/min. However, driving pressure was unstable, In the second type, we made two modification upon the principle:the bypass line and the isolator. In this model, the driving pressure is stabilized and the energy converting efficiency was improved.
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