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Trial Construction of Animal Breeding Cabinet for Exposing to Tritium Gas

Research Project

Project/Area Number 02559012
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 広領域
Research InstitutionHiroshima University

Principal Investigator

YAMAMOTO Osamu  Hiroshima University Faculty of Sciences, Professor, 理学部, 教授 (80034627)

Co-Investigator(Kenkyū-buntansha) OKUNO Hiroshi  Chiyoda Hoanyohin Co., Technician, 大阪営業所技術課, 課長
KAWAKATSU Shunji  Chiyoda Hoanyohin Co., Technician, 営業企画部技術課, 副主査
KOZUKA Masao  Chiyoda, Hoanyohin Co., Technician, 営業企画部技術課, 課長
狐塚 正夫  千代田保安用品株式会社, 営業企画部技術課, 課長
Project Period (FY) 1990 – 1991
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥13,800,000 (Direct Cost: ¥13,800,000)
Fiscal Year 1991: ¥5,500,000 (Direct Cost: ¥5,500,000)
Fiscal Year 1990: ¥8,300,000 (Direct Cost: ¥8,300,000)
KeywordsTritium / Radioisotope / Nuclear Fusion / Animal Breeding / Closed Cabinet / Radiation Exposur / Radiation Biological Effect / Tritium Gas / 動物実験用フ-ド / トリチウムガス曝射 / トリチウムガス回収 / 放射線被曝 / 放射線影響 / マウス / 放射線曝露
Research Abstract

Our trial manufacture of a glove box has successfully completed in 1990. An apparatus for tritium gas exposure and an apparatus for tritium gas collection were made in 1991. The summary is as follows :
1. Glove Box
This glove box is a large chamber as the frame of Animal Breeding Cabinet, which is composed of an outer box and an inner box. It is hard airtight for any kinds of experiments. It has no leak of tritium gas to the experimental room. It is made of SUS-304, which size is(Wd7OO + Wu550)x L1200 x H900 mm. But the front part is made of transparent acryl.
2. Apparatus for Tritium Gas Exposure
This apparatus is a part of the Animal Breeding Cabinet, in which small animals can be exposed to tritium gas. Tritium gas is introduced to the body of small animals by inhalation. It is composed of a chamber for exposing to tritium gas and animal holders. These are made of tr, ansparent acryl through which the behavior of small animals can be observed.
3. Apparatus for Tritium Gas Collection
This apparatus is used for the collection of tritium gas discarded. The path of tritium gas is hard airtight and is safely and reliably protective. This gas collector is composed of a heating catalytic system, a cooling absorber system, and0a circular system. The heating catalytic system can be kept at 300゚C. In the cooling absorber system tritiated water can be traped after cooling. The circular system acts with a disframe pump.
After completion of glove box, we tried to breed small animals'with tritiated water vapor as a preparatory experiment. Tritium absorption yield curbs to plateau by time were obtained.

Report

(3 results)
  • 1991 Annual Research Report   Final Research Report Summary
  • 1990 Annual Research Report
  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] Yamamoto,Osamu: "HTO oral administration in mice.I.Threshold dose rata for haematopoietic death." International Journal of Radaition Biology. 57. 543-549 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yamamoto,Osamu: "HTO oral administration in mice.II.Threshold dose rate for Lymphomatous death." International Journal of Radiation Biology.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yamamoto,Osamu: "HTO oral administration in mice.III.Threshold dose for lymphomatous death obtained from exposures in different periods." International Journal of Radiation Biology.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yamamoto, Osamu: "HTO oral administration in mice. I. Threshold dose rate for haematopoietic death." International Journal of Radiation Biology. 57. 543-549 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yamamoto, Osamu: "HTO oral administration in mice. II. Threshold does rate for lymphomatous death." International Journal of Radiation Biology.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yamamoto, Osamu: "HTO oral administration in mice. III. Threshold dose for lymphomatous death obtained from exposures in different periods." International Journal of Radiation Biology.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] Yamamoto,Osamu: "HTO oral administration in mice.I.Threshold dose rate for haematopoietic death." International Journal of Radiation Biology. 57. 543-549 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] Yamamoto,Osamu: "HTO oral administration in mice.II.Threshold dose rate for lymphomatous death." International Journal of Radiation Biology.

    • Related Report
      1991 Annual Research Report
  • [Publications] Yamamoto,Osamu: "HTO oral administration in mice.III.Threshold dose for lymphomatous death obtained from exposures in different periods." International Journal of Radiation Biology.

    • Related Report
      1991 Annual Research Report
  • [Publications] O.Yamamoto et al.: "Lowーdose rate effect of tritium betaーrays on transfection activity of phage DNA related to an oxidative species different from・OH,HO^〓_2,O^〓_2,and H_2O_2." Biochem.Int.20. 903-911 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] O.Yamamoto et al.: "HTO oral administration in mice.I:threshold dose rate for haematopoietic death." Int.J.Radiat.Biol.57. 543-549 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] O.Yamamoto et al.: "RBE of HTO to ^<60>Co gammaーrays obtained by using a plasmidcontained E__ー.<coli>___ー." J.Radiat.Res.

    • Related Report
      1990 Annual Research Report
  • [Publications] O.Yamamoto et al.: "HTO oral administration in mice.II:threshold dose rate for lymphoma induction." Int.J.Radiat.Biol.

    • Related Report
      1990 Annual Research Report
  • [Publications] O.Yamamoto et al.: "HTO oral administration in mice.III:threshold dose for lymphoma induction." Int.J.Radiat.Biol.

    • Related Report
      1990 Annual Research Report
  • [Publications] O.Yamamoto et al.: "Tritiated water experimental facilities for biochemical and biological use." J.Radiat.Res.

    • Related Report
      1990 Annual Research Report

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Published: 1990-04-01   Modified: 2016-04-21  

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