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Study of effects of noise on automic nervous system

Research Project

Project/Area Number 02670213
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Immunology
Research InstitutionDepartment of Hygiene, Asahikawa Medical College

Principal Investigator

YAMAMURA K.  Asahikawa Medical College, Hygiene, Professor, 医学部, 教授 (80109959)

Co-Investigator(Kenkyū-buntansha) MATSUI T.  Asahikawa Medical College, Hygiene, Assistant, 医学部, 助手 (00219370)
Project Period (FY) 1990 – 1991
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1991: ¥800,000 (Direct Cost: ¥800,000)
Keywordsultrasound / EP / CM / AP / Endocochlear Potential(EP) / Cochlear Microphonics(CM) / Action Potlntial(AP) / Action Potential(AP)
Research Abstract

There are only a few studies investigating the effect of ultrasound on hearing. Authors investigated experimentally the effect of ultrasound with moderate sound level for long time exposure to the inner ear using electrophysiological methods established already. Checking the coclear microphonics (CM), the action potential (AP) and the endocochlear potential (EP), the following results were obtained. Several kind (10 kHz, 16 kHz, 22 kHz, 28 kHz) of lbng exposure of moderate sound level of low frequency ultrasound below 100 dB SPL induced remarkable changes in CM, AP(elevation of threshold and decrease of maximum output voltage), and especially in EP (decrease of the absolute value of negative potential in previous report (Ishida, et al.)). In this report using 108 albino guinea pigs, authors investigated the effect of ultrasound of 19 kHz and 25 kHz with moderate sound level of long exposure on the function of the cochlea.
As an explanation of effect of low frequency ultrasound on the in … More ner ear function, especially changes of EP, the stimulus of ultrasound to autonomic nervous system of the cochlea was considered.
Many complaints were induced by low frequency ultrasound in industrial workers. Non auditory effects induced by ultrasound, namely, tinnitus, headaches, fatigue etc., was reported in many cases of exposure. However, there are only a few studies investigating the effect of ultrasound. By examining 218 albino guinea pigs, authors investigated experimentally the effect of ultrasound with moderate sound level for long time exposure to inner ear using blectrophysiological method. Checking the cochlear microphonics (CM), the action potential (AP) and the endocochlbar potential (EP), the following results were obtained. Several king (10 kHz, 16 kHz, 22 kHz, 28 kHz) of long exposure of moderate sound level of low frequency ultrasound below 100 dB SPL induced remarkable changes in CM, AP (Clevation of threshold and decrease of maximum output voltage), and especially in EP (decrease of absolute value of negative potential). Less

Report

(3 results)
  • 1991 Annual Research Report   Final Research Report Summary
  • 1990 Annual Research Report
  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] T.Fujita,T.Sugisawa,T.Matsui,K.Yamamura,et al.: "Effects of 250 and 500 Hz Tone Exposure on the Inner Ear of Guinea Pigs as Determined by Electrophysiological Techniques" ORL. 53. 147-152 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] K.Yamamura,T.Sugisawa,T.Matsui,et al.: "Study of the Effect of 350 Hz Tone Exposure on Electrophysiological Function of the Inner Ear of Guinea Pigs" ORL. 8 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] A.Ishida,T.Matsui,K.Yamamura: "Effects of Low Frequency Ultrasound on the Inner Ear (Guinea-Pigs)-Electrophysiological Study-" Archives of Oto-Rhino-Laryngology.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] A.Ishida,T.Sugisawa,K.Yamamura: "Effects of Low Frequency Ultrasound on the Inner Ear (Guinea-Pigs)" Hearing Research.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 山村 晃太郎: "ヒトと動物の聴覚" 遺伝. 46(2). 20-24 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T. Fujita, T. Sugisawa, T. Matsui, K. Yamamura et al.: "Effects of 250 and 500 Hz Tone Exposure on the Inner Ear of Guinea Pigs as Determined by Electrophysiological Techniques" ORL. 53. 147-152 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] K. Yamamura, T. Sugisawa, T. Matsui et al: "Study of the Effect of 350 Hz Tone Exposure on Electrophysiological Function of the Inner Ear o Guinea Pigs" ORL.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] A. Ishida, T. Matsui, K. Yamamura: "Effects of Low Frequency Ultrasound on the Inner Ear (Guinea-Pigs) - Electrophysiological Study -" Archives of Oto-Rhino-Laryngology.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] A. Ishida, T. Sugisawa, K. Yamamura: "Effects of Low Frequency Ultrasound on the Inner Ear (Guinea-Pigs)" Hearing Research.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] T.Fujita,T.Sugisawa,T.Matsui,K.Yamamura et al.: "Effects of 250 and 500 Hz Tone Exposure on the Inner Ear of Guinea Pigs as Determined by Electrophysiological Techniques" ORL. 53. 147-152 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] K.Yamamura,T.Sugisawa,T.Matsui,et al.: "Study of the Effect of 350 Hz Tone Exposure on Electrophysiological Function of the Inner Ear of Guinea Pigs" ORL. 8 (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] A.Ishida,T.Matsui,K.Yamamura: "Effects of Low Frequency Ultrasound on the Inner Ear (GuineaーPigs)ーElectrophysiological Studyー" Archives of OtoーRhinoーLaryngology.

    • Related Report
      1991 Annual Research Report
  • [Publications] A.Ishida,T.Sugisawa,K.Yamamura: "Effects of Low Frequency Ultrasound on the Inner Ear (GuineaーPigs)" Hearing Research.

    • Related Report
      1991 Annual Research Report
  • [Publications] 山村 晃太郎: "ヒトと動物の聴覚" 遺伝. 46(2). 20-24 (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] K.Yamamura,S.Saitoh,T.Fujita,Y.Sawada,H.Ohno: "Electrophysiogical determinations of the effects of 1kHz noise exposure on the highーfrequency hearing of guinea pigs" European Archives of OtoーRhinoーLaryngology. 247. 206-210 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] T.Fujita,T.Sugisawa,T.Matsui,M.Takahashi,N.Inada,A.Ishida,K.Yamamura: "Effects of 250 and 500 Hz Tone Exposure on the 1nner Ear of Guinea Pigs as Deternined by Electrophysiological Techniques" ORL.

    • Related Report
      1990 Annual Research Report

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Published: 1991-04-01   Modified: 2016-04-21  

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