| Project/Area Number |
02670547
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | EHIME UNIVERSITY |
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Principal Investigator |
IWAHASHI Kanji (1991-1992) EHIME UNIVERSITY HEALTH ADMINISTRATION CENTER PROFESSOR, 保健管理センター, 教授 (00110825)
恒川 謙吾 (1990) 愛媛大学, 医学部, 教授 (40025557)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUDA Ryoichi EHIME UNIVERSITY SCHOOL OF MEDICINE, ASSISTANT, 医学部, 助手 (10243784)
福原 稔之 愛媛大学, 医学部・附属病院, 助手 (00228925)
多森 芳樹 愛媛大学, 医学部・附属病院, 助手 (50217204)
岩橋 寛治 愛媛大学, 医学部, 助教授 (00110825)
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| Project Period (FY) |
1990 – 1992
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| Project Status |
Completed (Fiscal Year 1992)
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| Budget Amount *help |
¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1992: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1991: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1990: ¥600,000 (Direct Cost: ¥600,000)
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| Keywords | Esophagus / Cat / Innervation / HRP / Sensory Nerve / Pain / Retrograde Axonal Transport / Spinal Dorsal Root Ganglion |
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| Research Abstract |
Using the HRP method, the afferent innervation of the esophagus was studied in the cat.
The cervical esophagus had bilateral afferent innervation via dorsal root ganglia(DRG) cells from C1 to T9. The main pathways traveled through the phrenic and greater splanchnic nerves. The thoratic,lower esophagus also had bilateral afferent innervation via DRG cells from C5 to T13. The main pathway traveled through the greater splanchnic nerve. There were other pathways as well,sympathetic cardiac branch via the stellate ganglion and branches from the cervical and thoracic sympathetic trunk.
Vagal afferent innervation was relatively predominant in the cervical esophagus, while sympathetic innervation was predominant in the thoracic, lower esophagus.
The cervical esophagus received sympathetic postganglionic innervation via the paravertebral ganglia between the superior cervical ganglia and the T8 sympathetic ganglia. The thoracic, lower esophagus also received sympathetic post-ganglionic innervation via the paravertebral ganglia between the superior cervical ganglia and the T12 sympathetic ganglia and the prevertebral ganglia.
The parasympathetic preganglionic neurons innervating cervical esophagus were located in the nucleus ambiguous, but in the nucleus ambiguous and dorsal nucleus of the vagal nerve in the case of the thoracic,lower esophagus.
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