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Study on pathology hemorrhagic gastric ulcer and treatments by means of high-technological modalities, with special reference to short and long term prognosis i n the high-age group

Research Project

Project/Area Number 02670587
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionKitasato Univ

Principal Investigator

HIKI Yoshiki  Kitasato University School of Medicine, Professor, 医学部, 教授 (10050395)

Co-Investigator(Kenkyū-buntansha) SAIGENJI Katsunori  北里大学, 医学部, 教授 (70050581)
TSUKAMOTO Hideto  北里大学, 医学部, 講師 (60146420)
SHIMAO Hitoshi  北里大学, 医学部, 講師 (00146408)
MIENO Hiroyoshi  北里大学, 医学部, 講師 (80118843)
SAKAKIBARA Yuzuru  北里大学, 医学部, 助教授 (00050451)
蔵並 勝  北里大学, 医学部, 助手 (80170075)
Project Period (FY) 1990 – 1992
Project Status Completed (Fiscal Year 1992)
Budget Amount *help
¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1992: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1991: ¥500,000 (Direct Cost: ¥500,000)
KeywordsHemorrhagic gastric cancer / Hish-technological modalities / Short-term prognosis / Long-term prognosis / High-age group / Mortality rate / Conservative treatment / Surgical death / 高齢者の胃切除術 / 術後合併症 / 術後愁訴 / Performance status / レーザー治療 / ヒータープローブ / 永久止血 / 高齢者 / 高位潰瘍 / 左胃動脈領域 / 大量出血 / 合併基礎疾患 / 手術死亡 / 先端技術による治療 / 緊急内視鏡検査 / 顕出血例 / 最終出血 / 短期要後 / 緊急手術 / 止血成功 / ヒ-タ-プロ-ブ法
Research Abstract

Our present study was conducted by co-operation between Department of International medicine and Surgery of our hospital, which was highly significant because the results were comprehensive without a bias toward either department.
The present report describes whether or not emergency operations have decreased because of progress in various high technological endoscopic hemostatic method for hemorrhagic ulcer and short-term and long-term prognosis after conservative therapy.
As for the results of conservative treatment, the rate of short-term prognostic hemostasis was 81.3%.
Of the long-term prognostic cases, ulcers recurred in 50%, accompanied by recurrent bleeding in 34.8%.
These patients were again treated by conservative therapy, and hemostasis was successful.
The mortality rate following conservative therapy was 13.7% in the first period and 11.0% in the later period.
The surgical mortality rate was 6.0% in the first period and 5.4% in the later period.
There was no surgical death among the patients under going palliative operation. Our therapeutic policy for hemorrhagic ulcer will be described based on these findings.

Report

(4 results)
  • 1992 Annual Research Report   Final Research Report Summary
  • 1991 Annual Research Report
  • 1990 Annual Research Report
  • Research Products

    (36 results)

All Other

All Publications (36 results)

  • [Publications] 比企 能樹: "Endoscopic treatment of gastric cancer" Surgical Endoscopy. 5. 11-13 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Clinical treatment of gastrodeuodenal bleeding" Gastroenterologia Japonica. 26. 43-46 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 嶋尾 仁: "進行胃癌の内視鏡治療" 治療. 73. 35-42 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 比企 能樹: "外科からみた内視鏡治療の現況" Gastroenterological Endoscopy. 33(10). 2285-2299 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 比企 能樹: "胃癌のレーザー療法" 臨床外科. 46(9). 1061-1066 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Laser therapy for early gastrointestinal carcinoma" Surgical Clinics of North America. 72(3). 571-580 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 比企 能樹: "消化器内視鏡治療マニュアル" (株)南山堂, 265 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Endoscopic treatment of gastric cancer." Surgical Endoscopy. 5. 11-13 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Clinical treatment of gastroduodenal bleeding" Gastroenterol. Jpn.26. 43-36 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Surgical treatment for gastric cancer" Gastroenterol. Endosc.33(10). 2285-2299 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Laser endoscopy for early gastric cancer" Journal of Clinical Surgery. 46(9). 1061-1066 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Laser therapy for early gastrointestinal carcinoma" Surgical Clinics of North America. 72(3). 571-580 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: "Manual of Therapeutic Endoscopy in Gastroenterology" Nanko-do. 265 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Y.Hiki: Nanko-do. Manual of Therapeutic Endoscopy in Gastroenterology, 265 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 比企 能樹: "内視鏡を用いた治療" 消化器外科. 15(6). 1234-1241 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 桜本 信一: "胃の内視鏡下外科手術 ー急性出血に対する止血ー" 外科. 54(12). 1346-1353 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 塚本 秀人: "急性胃粘膜病変" 外科治療. 66(5). 648-650 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] Y.Hiki: "Laser Therapy for Early Upper Gastrointestinal Carcinoma" Surgical Clinics of North America. 72(3). 571-580 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 比企 能樹: "消化器癌のレーザー内視鏡治療と外科治療について" 癌治療と宿主. 4(1). 25-32 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 塚本 秀人: "消化管出血に対する内視鏡適治療" 日本医師会雑誌. 109(1). MN13-15 (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 比企 能樹: "消化器内視鏡治療マニュアル" (株)南江堂, 265 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 比企 能樹: "外科医のための消化器内視鏡" 中外医学社, 317 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 西元寺 克禮: "H2受容体拮抗剤治療下胃潰瘍の難治要因の検討" Gastroenterological Endoscopy. 32ー6. 1354-1360 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] 竹本 忠良,西元寺 克禮: "老年者胃潰瘍の特性と治療" Progress in Medicine. Vol.11ー9. 207-233 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 比企 能樹: "Endoscopic treatment of gastric cancer" Surgical Endoscopy. 5. 11-13 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] 比企 能樹: "Endoscopic Surgeryとレ-ザ-" 日本レ-ザ-医学会誌. 12ー3. 9-13 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] 比企 能樹: "Clinical treatment of gastroduodenal bleeding" Gastroenterologia Japonica. 26. 43-46 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] 嶋尾 仁,比企 能樹: "進行胃癌の内視鏡治療" 治療. 73. 35-42 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 比企 能樹: "今日の消化器疾患治療指針" 医学書院, 171-172 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Y.Hiki.etc: "Clinical Treatment of Gastroduodenal Bleeding" Abstracts:The Third International Symposium of the Japanese Society of Gastroenterology. 17- (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 塚本 秀人 他: "急性胃粘膜病変(AGML)の成因" 胃と腸. 24. 645-652 (1989)

    • Related Report
      1990 Annual Research Report
  • [Publications] 比企 能樹 他: "胃癌・出血性潰瘍" 臨床外科. 45. 177-186 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 塚本 秀人 他: "手術侵襲によるAGMLの内視鏡像とその経過" 消化器内視鏡. 2. 734-748 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 塚本 秀人 他: "大量吐血に対する非手術療法とその限界" 消化器外科. 13. 163-168 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 比企 能樹: "消化器外科におけるレ-ザ-装置" 手術. 44. 849-853 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 比企 能樹: "消化器内視鏡治療手技" 中外医学社, 210 (1990)

    • Related Report
      1990 Annual Research Report

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Published: 1991-04-01   Modified: 2016-04-21  

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