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The study of preventive effect for thrombosis using platelet aggregation inhibitory activity of foods.

Research Project

Project/Area Number 02680076
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field 家政学
Research InstitutionSugiyama Jogakuen University

Principal Investigator

NAMIKI Kazuko  Sugiyama Jogakuen University, School of Life Studies, Professor, 生活科学部, 教授 (90065011)

Co-Investigator(Kenkyū-buntansha) YAMANAKA Midori  Sugiyama Jogakuen University school of Life Studies, Research Associate, 生活科学部, 助手 (60139962)
Project Period (FY) 1990 – 1991
Project Status Completed (Fiscal Year 1991)
Budget Amount *help
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1991: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1990: ¥1,000,000 (Direct Cost: ¥1,000,000)
KeywordsPlatelet aggregation inhibitory activity of vegetable juice / Platelet aggregation inhibitory activity of fruite juice / Platelet aggregation inhibitory activity of cooked sardine / Platelet aggregation inhibitory activity of processed sardine / Platelet aggregation inhibitory activity of foods / Protective effect for thrombosis by foods / Platelet aggregation inhibitory activity of tea extract
Research Abstract

Aiming to prevent heart and brain diseases such as myocardial and cerebral infarction by daily diet, inhibitory effect of water extracts prepared from various kinds of food on platelet aggregation of human blood was examined by in vitro test using turbidimetry. Many fruits and vegetables such as garlic, tomato, spinach, melon, papaya and grapefruit showed marked effect. Among fishes and shells tested, sardine and mackerel known as rich in EPA and DHA content showed eminent effect but the activity was shown to be considerably changed by the ir processing and cooking depending residuai amounts of these HUSFA.
Based on effective dilution of the extract in in vitro test, the inhibitory activity of various foods was evaluated and roughly scored for each main food. From this evaluation, a special dish was designed and cooked in combination of effective food materials, and eating test of this special dish with five persons for 3 days gave apparent decrease in their platelet aggregation activity of blood.

Report

(3 results)
  • 1991 Annual Research Report   Final Research Report Summary
  • 1990 Annual Research Report
  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] 並木 和子: "茶浸出液の血小板凝集抑制作用" 日本食品工業学会誌. 38. 189-195 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 並木 和子: "茶抽出成分の血小板凝集抑制作用" フレグランスジャ-ナル. 11. 67-70 (1990)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 並木 和子: "ビラジン類縁化合物の血小板凝集抑制作用" 日本食品工業学会誌.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 山中 みどり: "イワシ調理方法別血小板凝集抑制作用" 日本家政学会誌.

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 並木 和子: "茶の科学(村松敬一郎編)" 朝倉書店, 9 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 並木 和子: "こんな野菜が血栓をふせぐ(共著)" 講談社(ブル-バックス), 47 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] K. Namiki, M. Yamanaka, C. Tateyama, M. Igarashi, M. Namiki.: "Platelet Aggregation Inhibitory Activity of Tea Extracts." Nippon Syokuhin Kogyo Gakkaishi. 38. 189-195 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] K. Namiki: "Platelet aggregation inhibitory of tea components" Fragrans Journal. 11. 67-70 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1991 Final Research Report Summary
  • [Publications] 並木 和子: "茶浸出液の血小板凝集抑制作用" 日本食品工業学会誌. 38. 189-195 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 並木 和子: "茶抽出成分の血小板凝集抑制作用" フレグランスジャ-ナル. 11. 67-70 (1990)

    • Related Report
      1991 Annual Research Report
  • [Publications] 並木 和子: "ピラジン類緑化合物の血小板凝集抑制作用" 日本食品工業学会誌.

    • Related Report
      1991 Annual Research Report
  • [Publications] 山中 みどり: "イワシ調理方法別血小板凝集抑制作用" 日本家政学会誌.

    • Related Report
      1991 Annual Research Report
  • [Publications] 並木 和子(村松 敬一郎遍): "茶の科学" 朝倉書店, 9 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 並木 和子: "こんな野菜が血栓をふせぐ(共著)" 構談社(ブル-バックス), 47 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 並木 和子: "茶浸出液の血小板凝集抑制作用" 日本食品工業学会誌. 38. (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 並木 和子: "ピラジン類緑化合物の血小板凝集抑制作用" 日本食品工業学会誌.

    • Related Report
      1990 Annual Research Report
  • [Publications] 山中 みどり: "イワシ調理法別血小板凝集抑制作用" 日本家政学会誌.

    • Related Report
      1990 Annual Research Report

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Published: 1990-04-01   Modified: 2016-04-21  

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