| Budget Amount *help |
¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1991: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1990: ¥900,000 (Direct Cost: ¥900,000)
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| Research Abstract |
Vibration injuries are occupational diseases with disturbances of peripheral circulation, which are brought on when vibration is transmitted to human body from vibratory tools and niachines. It is very important to clarify the mechanism about the attach of this disease because of the protection of disturbance and the establishment of radical cure. There has been only a little amount of information about the fundamental mechanism. In particular, the biomechanical study is urgently needed. The purposes of this work are to detect gas bubbles in blood subjected to a pulsation, to make clear experimentally thO condition of bubble generation, and to find theoretically the bubble behavior in blood. A decompressive and vibratory apparatus of bubble generation is made, which is possessed of the experimental conditions about the depressorization DELTAP=0-650mmHg, the vibratory frequency f=0-40Hz, and the amplitude A=4mm. The tested liquids are dogs'blood, in addition to, isotonic sodium chloride solution, tap water, and oil, for comparison. The following matters are found from the experimental results. It is easy to generate bubbles in pulsating blood, as compared with the other tested liquids. An increase of vibratory frequency is promoted the formation of bubbles. Under the condition of atmospheric pressure, the bubbles generate in blood when the frequency is greater than 28Hz. The diameters of bubbles are about 0.2mm. It is clear from the theoretical study of bubble motion that the impulsive pressure occurs when the bubble oscillates with non-linear resonance in blood. The generated pressure is small with a decrement of hematocrit, and is large with an increment of bubble size.
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