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Hemodynamic Analysis of Portal Hypertension and Clinical Application of the Vascular Pattern of the Lower Esophagus

Research Project

Project/Area Number 02807122
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionKYUSHU UNIVERSITY

Principal Investigator

HASHIZUME Makoto  Kyusyu University, Department of Medicine, Assistant Professor, 医学部, 講師 (90198664)

Project Period (FY) 1990 – 1992
Project Status Completed (Fiscal Year 1992)
Budget Amount *help
¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1992: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1991: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1990: ¥900,000 (Direct Cost: ¥900,000)
KeywordsPortal hypertension / Esophageal varices / Gastric varices / Combined therapy / sclerotherapy / Giant bar type / Budd-Chiari症候群 / 非観血的静脈瘤内圧測定器 / 透明型内視鏡下静脈瘤結紮術 / 経皮経肝的門脈造影 / 実験モデル
Research Abstract

We reported an angioarchitectural classification of the lower esophagus by a selective left gastric venography in 1989; palisading and bar types. The purpose of this project was to investigate the clinical significance of the vascular pattern of the lower esophagus.
We examined the clinical characteristics, percutaneous trans-hepatic portography, endoscopic findings, color doppler echography, and non-invasive esophageal variceal pressure measurement and so on in 1,200 patients with esophageal varices. The bar type of the esophageal varices was likely to be resistent to sclerotherapy and easily to recur after the treatment, especially "giant-bar type" esophageal varices should be considered a combined therapy of sclerotherapy with Hassab's operation.

Report

(4 results)
  • 1992 Annual Research Report   Final Research Report Summary
  • 1991 Annual Research Report
  • 1990 Annual Research Report
  • Research Products

    (80 results)

All Other

All Publications (80 results)

  • [Publications] 杉町圭蔵他: "食道静脈瘤に対する治療法の選択" 臨床外科. 47. 1219-1225 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K.Tanoue,et al.: "Effects of endosccgic injection sclerotherafy on portal hypertensive gastropathy ia grospective study" Gastrointest Endosc. 38. 582-585 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Hashizume,et al: "Laparoscopic splenectomy with an ultrasonic dissector" New England Journal of Medicine. 327. 438 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Hashizume,et al: "Endoscopic injection sclerotherapy for 1,000 patients with esophageal varices : a nine-year prospective study" Hepatology. 15. 69-75 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Hashizume,et al: "Endoscopic ligation of esophageal vaduces adverse effects of injection sclerotherapy" Gastrointest Endosc. (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Hashizume,et al: "Endoscopic ligation of esophageal vaduces adverse effects of injection sclerotherapy" Gastrointest Endosc. (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Hashizume,et al: "Laparoscopic ligation of splenic artery aneurysm" Surgery. (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M.Hashizume,et al: "Diseases of the Esophagus" Springer-Verlag, (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 橋爪 誠: "新一般外科術前,術中,術後管理" へるす出版, (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] Keizo Sugimachi, et al.: "The Treatment for the esophageal varices." Rinshougeka (in Japanese). 47. 1219-1225 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] K Tanoue, et al.: "Effects of endoscopic injection sclerotherapy on partal hypertensive gastropathy: a prospective study." Gastrointest Endosc. 38. 582-585 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M Hashizume, et al.: "Laparoscopic splenectomy with on ultrasonic dissector." New England Journal of Medicine. 327. 438 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M Hashizume, et al.: "Endoscopic injection sclerotherapy for 1,000 paitents with esophageal varices: a nine-year prospective study." Hepatology. 15. 69-75 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M Hashizume, et al.: "Endoscopic ligation of esophageal varices reduces adverse effects of injection sclerotherapy." Gastrointest Endosc.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] M Hashizume, et al.: "Laparoscopic ligation of splenic artery aneurysm." Surgery.

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1992 Final Research Report Summary
  • [Publications] 杉町 圭蔵 他: "食道静脈瘤に対する治療法の選択" 臨床外科. 47. 1219-1225 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] K.Tamoue,et al: "Effeas of endoscopic injection sclerotherapy on pertal bypertensive gastropathy:a prospective study." Gastrointest.Endosc. 38. 582-585 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Hashizume,et al: "Laparoscopic splenectomy with an ultrasonic dissector" New England Journal of Medicine. 327. 438- (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Hashizume,et al: "Endoscopic injection sclerotherapy for 1.000 patients with esophageal varices: a nine-year prospective study" Hepatology. 15. 69-75 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Hashizume,et al: "Endoscopic ligation of esophageal varices reduces adverse effects of injection sclerotherapy" Gastrointest Endosc. (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Hashizume,et al: "Laparoscopic ligation of splenic artery anenrysm" Surgery. (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] M.Hashizume et al: "Diseases of the Esophagus" Springer-Verlag, (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 橋爪 誠: "新一般外科術前,術中,術後管理" へるす出版, (1993)

    • Related Report
      1992 Annual Research Report
  • [Publications] 杉町 圭蔵: "門脈圧亢進症の病態と治療" 脈管学. 31. 1423-1427 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 橋爪 誠: "食道静脈瘤治療後、遺残再博胃静脈瘤に対する硬化療法の適応と手技" 消化器内視鏡. 3. 1445-1451 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 橋爪 誠: "食道静脈瘤900症例に対する硬化療法の検討" 腹部救急治療の進歩. 11. 59-63 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 橋爪 誠: "胃静脈瘤の血管構築" 外科治療. 164. 104-110 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Laparoscopic splenectomy for idiopathic thrombocytopenic purpura using an Ultrasonic Dissector" Lancet.

    • Related Report
      1991 Annual Research Report
  • [Publications] Haトhizume M: "Prospective randomized trial of endoscopic injection sclerotherapy versus esophageal variceal ligation" Br J Surg.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "The strategy of treatment for gastric variceal bleeding" J Gastroenterol Hepatol.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Sclerotherapyーresistant oesophageal varices with enormously cephalad collateral vessels predictable using portography" Eur Surg Res.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Percutaneous transhepatic angioplasty in BuddーChiari syndroma" Hepatology.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Vascular anatomy and clinical management of duodenal varices" Gastroenterol.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Acute,Temporary renal failure after injection sclerotherapy" Liver.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Giant barーtype esophageal varices not eradicated by repeated injection sclentherapy" Gastrointest Endosc. 37. 187-189 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Endoscopic injection sclerotherapy for 1000patients with esophageal varices:A 9ーyear prospective study" Hepatology. 15. 59-75 (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "A new ligation teehnique for laparoscopic vascular surgery" Surgery.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "The strategy of treatment for gastric variceal bleeding" J Gastroenterol Hepatol.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Sclerotherapyーresistant oesophageal varices with enormously cephalad collateral vessels predictable using portography" Eur Surg Res.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Giant barーesophageal varices not eradicated by repeated injectionーsclerotherapy" Gastrointestinal Endoscopy. 37. 187-189 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 北野 正剛: "スライディングチュ-ブ法の利用と問題点" 臨床消化器内科. 105-189 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Laparoscopic ligation of splenic artery aneurysn" Surgery.

    • Related Report
      1991 Annual Research Report
  • [Publications] Hashizume M: "Endoscopic injection sclerotherapy for 1000patients with esophageal varices A 9ーyear prospective stydy" Hepatology. 15. 69-75 (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] Kitano S: "Overーtube is preferable to freeーhand technique to avoid recurrence of varices after endoーscopic injection Sclerotherapy:A prospective randomized trial" Int Surg.

    • Related Report
      1991 Annual Research Report
  • [Publications] Kitano S: "Comparative effect of 5% ethanolamine oleate versus 5% ethanolamine oleate plus 1% polidocanol for sclerosing esophageal varices" HepatoーGastroenterol.

    • Related Report
      1991 Annual Research Report
  • [Publications] Tanoue K: "A rat model of esophageal varices purpura using an Ultrasonic Dissector" Hepatology.

    • Related Report
      1991 Annual Research Report
  • [Publications] Tanoue K: "Effects of endoscopic injection sclerotherapy on portal Hypertensive gastropathy" Gastrointest Endosc. 14. 802-805 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Ariyoshi T: "Clinical and angiographic assessment and treatment of patients with recurrent varices after transabdominal transection of the esophagus" Arch Surg.

    • Related Report
      1991 Annual Research Report
  • [Publications] 杉町 圭蔵: "PO case study外科疾患ケ-ススタディ59例のPO研修 症例9「突然、大量出血をきたし緊急入院した中年男性」" 医学書院, 326 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 杉町 圭蔵: "抗アルドステロン薬その歴史と展望 開腹術後の水分、電解質代謝異常の改善にカンレン酸(ソルダクトン)が有効であった1例" スタンダ-ド マッキンタイヤ, 26 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 杉町 圭蔵: "厚生省特定疾患門脈血行異常症調査研究班平成2年度研究報告書 食道静脈瘤硬化療法による治療困難例の検討" 厚生省小幡班, 274 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 杉町 圭蔵: "厚生省特定疾患門脈血行異常症調査研究班平成2年度研究報告書 食道静脈瘤硬化療法後の再発機序に関する検討" 厚生省小幡班, 274 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 杉町 圭蔵: "癌手術後の水、電解質異常とその管理 利尿薬の効果的な使い方をめぐって" メディカルトリビュ-ン, 63 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 橋爪 誠: "胆石症に対する新しい治療の動向 国立福岡中央病院地域医療研修セミナ-テキスト" 陽文社, 14 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 橋爪 誠: "経皮経肝門脈造影と胃食道静脈瘤治療への応用" 日消外会誌. 23. 985-989 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 橋爪 誠: "選択的シャント術食道静脈瘤ー治療の進歩1990" 最新医学. 45. 1152-1155 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 杉町 圭蔵: "門脈圧亢進症(1)食道静脈瘤の血管構築外科病理" 外科治療. 63. 675-682 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 北野 正剛: "再出血予防法としての食道粘膜消滅法:食道静脈瘤硬化療法" 日本臨床. 48. 770-773 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 杉町 圭蔵: "経皮経肝門脈造影上、巨大Portaーsystemic Shuntを呈した12例の検討" 厚生省特定疾患・門脈血行異常症調査研究班.平成元年度研究報告書. 112-113 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 杉町 圭蔵: "硬化療法後の食道静脈瘤再発形成と再発予防対策" 厚生省特定疾患、門脈血行異常症調査研究班・平成元年度研究報告書. 194-195 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 杉町 圭蔵: "硬化療法後の胃静脈瘤出現機序に関する検討" 厚生省特定疾患、門脈血行異常症調査研究班・平成元年度研究報告書. 196-197 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 橋爪 誠: "経皮経肝静脈瘤塞栓術と硬化療法の併用による胃静脈瘤の治療" 腹部救急診療の進歩. 10. 705-710 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 北野 正剛: "食道静脈瘤に対する内科的治療" 臨床看護. 16. 1175-1179 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Beppu K: "Hepatology elsewhere:Endoscopic markers of impending variceal hemorrhage;correlation with the pressure in the varices." Hepatology. 11. 147-148 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hashizume M: "Endoscopic classification of gastric varices" Gastrointest Endosc. 36. 276-280 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hashizume M: "Eradication of esophageal varices recurring after portal nondecompressire surgery by injection sclerotherapy" Br J Surg. 77. 940-943 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hashizume M: "Hypercoagulopathy after injection of 5% ethanolamine oleate to sclerose esophageal varices" Hepatoーgastroenterol. 37. 565-568 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Wada H: "Hemodynamic and morphological changes in the dog kidney after injection of 5% ethanolamine oleate into the superior vena cava" Eur Surg Res. 22. 63-70 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] Tanoue K: "A rat model of esophageal varices" Hepatology.

    • Related Report
      1990 Annual Research Report
  • [Publications] Eguchi A: "High rate of portal thrombosis after splenectomyin patients with esophageal varices and idiopathic portal hypertension" Arch Surg.

    • Related Report
      1990 Annual Research Report
  • [Publications] Yamaga H: "Platelet Aggregability and PGI2/TXA2 Ratio after Endoscopic injection Sclerotherapy with Different Sclerosants" Eur Surg Res.

    • Related Report
      1990 Annual Research Report
  • [Publications] Ariyoshi T: "Clinical and argiographic assessment and treatment of patients with Recurrent Varices after transabdominal transection of the esophagas" Arch Surg.

    • Related Report
      1990 Annual Research Report
  • [Publications] Ohta M: "Splenic hyperkinetic state and splenic artery aneurysmin portal hypertension" Arch Surg.

    • Related Report
      1990 Annual Research Report
  • [Publications] 橋爪 誠: "食道静脈瘤900症例に対する硬化療法の検討" 腹部救急診療の進歩. 11. 59-63 (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] 橋爪 誠: "門脈圧亢進症(II)胃静脈瘤の血管構築" 外科治療. 64. (1991)

    • Related Report
      1990 Annual Research Report
  • [Publications] Hashizume M: "Endoscopic injection Sclerotherapy for 1,000 Patients with oesophageal varices and treated at kyushu University A 9ーyear prospective study" The Lancet.

    • Related Report
      1990 Annual Research Report
  • [Publications] Hashizume M: "Giant bar type esophageal varices nonーeradicated by repeated injection Sclerotherapy" Gastrointest Endosc.

    • Related Report
      1990 Annual Research Report
  • [Publications] 橋爪 誠: "胃静脈瘤の治療:食道静脈瘤:治療法の進歩消化器病セミナ-38" へるす出版, 204 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 北野 正剛: "上部消化管出血における私の処方II" 診療新社, 232 (1990)

    • Related Report
      1990 Annual Research Report
  • [Publications] 杉町 圭蔵: "内視鏡的硬化療法の基礎的検討と臨床評価に関する研究" ジェフ・コ-ポレ-ション, 330 (1990)

    • Related Report
      1990 Annual Research Report

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Published: 1990-04-01   Modified: 2016-04-21  

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