A Study on risk factors of gastrointestinal cancer in Taivan

Research Project

Project/Area Number	03042016
Research Category	Grant-in-Aid for international Scientific Research
Allocation Type	Single-year Grants
Section	Special Cancer Research
Research Institution	Kyoto Prefectural University of Medicine
Principal Investigator	KAWAI Keiichi Kyoto Prefectural University of medicine.Professor, 医学部, 教授 (50079745)
Co-Investigator(Kenkyū-buntansha)	劉輝雄劉輝雄内科胃腸科医院, 院長施壽全馬偕記念病院, 主治医師楊國郷馬偕記念病院, 主任翁昭紋台湾大学, 医学部, 主治医師林肇堂台湾大学, 医学部, 副教授王正一台湾大学, 医学部, 教授王徳宏台湾大学, 医学部, 教授 WATANABE Yoshiyuki Kyoto Prefectural University of medicine.Lecturer, 医学部, 講師 (00191809) YAMAGUCHI Toshiharu Kyoto Prefectural University of medicine.Lecturer, 医学部, 講師 (90111327) TSUCHIHASHI Yasunari Kyoto Prefectural University of medicine.Associate Professor, 医学部, 助教授 (50106390) TAKAHASHI Toshio Kyoto Prefectural University of medicine.Professor, 医学部, 教授 (50079828) CHUAN Shin-Shou Mackay Memorial Hospital YANG Kuo-Ching Mackay Memorial Hospital MIN Weng-Chao National Taiwan University Hospital LIN Jaw-Town National Taiwan University Hospital.Associate Professor WANG Cheng-Yi National Taiwan University Hospital.Professor WANG Teh-Hong National Taiwan University Hospital.Professor LIU Hui-Hsiung Liu Gastroenterologic Hospital 青池晟京都府立医科大学, 助教授 (00117871)
Project Period (FY)	1991 – 1992
Project Status	Completed (Fiscal Year 1992)
Budget Amount *help	¥4,000,000 (Direct Cost: ¥4,000,000) Fiscal Year 1992: ¥2,000,000 (Direct Cost: ¥2,000,000) Fiscal Year 1991: ¥2,000,000 (Direct Cost: ¥2,000,000)
Keywords	Stomach Cancer / Colorectal Cancer / Descriptive Epidemiology / Mortality Statistics / Clinical Statistics / Analytical Epidemiology / Risk Factor
Research Abstract	This study was conducted to reveal the frequency and distribution on stomach cancer and colorectal cancer in Taiwan and the risk factors of these diseases among Taiwanese. As for stomach cancer in Taiwan, the decreasing trend of mortality and the distribution of pathological types were almost the same as in Japan. Mortality statistics showed that the death rate from colon cancer was constantly higher than that from rectal cancer in Taiwan during the past 15 years. Clinical data also showed the colon cancer predominance among intestinal cancer patients. These are different from Japanese trend which showed the recent increasing of colon cancer. However, the pathological findings on colorectal cancer in Taiwan showed almost the same distribution as Japanese. Preliminary case-control study on dietary factors and past medical histories stomach cancer in Taiwan showed that the history of hypertension and the frequent intake (2-3 times/week or more) of spices decreased the risk significantly. A case-control study for colorectal cancer in Taiwan showed that daily intake of salty food significantly increased the risk and the frequent intake (1-2 times/week or more) of meat significantly decreased the risk. It is necessary to continue to study more on these possible risk factors of stomach cancer and colorectal cancer in details as these analyses were conducted on a small number of cases.