• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

THE ADVANCED RESERCH TO DEVELOP THE ARTIFICIAL HEART

Research Project

Project/Area Number 03404040
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Thoracic surgery
Research InstitutionThe University of Tokyo

Principal Investigator

FUZIMASA Iwao  Professor, Research Center for Advanced Science and Technology, The University of Tokyo, 先端科学技術研究センター, 教授 (30010028)

Co-Investigator(Kenkyū-buntansha) IMANISHI Kaoru  Research Associate, Faculty of Medicine, The University of Tokyo, 医学部, 助手 (70168516)
ABE Yusuke  Research Associate, Faculty of Medicine, The University of Tokyo, 医学部, 助手 (90193010)
IMACHI Kou  Professor, Faculty of Medicine, The University of Tokyo, 医学部, 教授 (10010076)
CHINZEI Tsuneo  Research Associate, Research Center for Advanced Science and Technology, The Uni, 先端科学技術研究センター, 助手 (20197643)
MABUCHI Kunihiko  Associate Professor, Research Center for Advanced Science and Technology, The Un, 先端科学技術研究センター, 助教授 (50192349)
米沢 貞実  東京大学, 医学部, 助手 (50221677)
Project Period (FY) 1991 – 1993
Project Status Completed (Fiscal Year 1993)
Budget Amount *help
¥32,100,000 (Direct Cost: ¥32,100,000)
Fiscal Year 1993: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1992: ¥6,600,000 (Direct Cost: ¥6,600,000)
Fiscal Year 1991: ¥23,300,000 (Direct Cost: ¥23,300,000)
KeywordsArtificial heart, / Actuator, / Artificial valve, / Continuous flow pump, / Pulsatile flow, / Micromachine, / Advanced technology, / Automatic control / 埋め込みポンプ / 連続流 / センサ / 末梢循環 / 人工筋肉 / 固体撮像素子 / 完全人工心臓 / アクチュエ-タ / 固定撮像素子 / 高速サチモグラフィ
Research Abstract

The objective of this study is to promote the artificial heart research and development under the aid of advanced technology. The following results have obtained in these 3 years.
Development of a micro artificial heart (1)Theoretical analysis and development of micro actuator drived with vibration energy. (2)Development of a small diameter artificial valve for a micro blood pump.
Research and development of new types of totally implantable artificial heart. (1)Development of flow transformed pulsatile total artificial heart. (2)Development of anew volumetric continuous flow blood pump and its application to a total artificial heart.
Development of a new automatic control logic of total artificial heart.
Development of new advanced technology to support the artificial heart reserch (1)Development of a sensor for intravascular measurement of blood catecholamine. (2)Development of new implantable apparatus to observe the microcirculation in situ using a direct contact CCD method. (3)Development of a ast scanning thermography system to analyze the dynamic changes in physiological state. (4)Deveropment of a new surface microscope for real time measurement of protein adsorbtion on an artificial heart material surface.

Report

(4 results)
  • 1993 Annual Research Report   Final Research Report Summary
  • 1992 Annual Research Report
  • 1991 Annual Research Report
  • Research Products

    (35 results)

All Other

All Publications (35 results)

  • [Publications] Kou Imachi: "The second and third model of the flow transformed pulsatile total artificial heart" ASAIO Journal. 38(3). M717-M721 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Kou Imachi: "Fabrication of a jellyfish valve for use in an artificial heart" ASAIO Journal. 38(3). M237-M242 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Iwao Fujimasa: "Micromachines-concepts,materials and mechanisms for new machines" Proceedings of the First International Conference on Intelligent Materials. 261-266 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Yusuke Abe: "Reciprocal of the peripheral vascular resistance(1/R)control method for the total artificial heart" Heart Replacement:Artificial Heart 4,Springer-Verlag Tokyo. 349-351 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Yusuke Abe: "A pulsatile total artificial heart by using precessional displacement pumps" Abstracts of the First Congress of the International Society for Rotary Blood pumps. 19 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Iwao Fujimasa: "Micromachining technology and bio-medical engineering" Applied Biochemistry and Biotechnology. 41(in press). (1994)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 藤正 巖: "マイクロマシン開発ノートブック" 秀潤社, 209 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Imachi, et al.: "The second and third model of the flow transformed pulsatile total artificial heart" ASAIO Jornal. 38(3). M717-M721 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] K.Imachi, et al.: "Fabrication of a jellyfish valve for use in an artificial heart" ASAIO Jornal. 38(3). M237-M242 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] I.Fujimasa: "Micromachines-concepts, materials and mechanisms for new machines" Proceedings of the First International Conference on Intelligent Materials. 261-266 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Y.Abe, et al.: "Reciprocal of the peripheral vascular resistance (1/R) control method for the total artificial heart" Heart Replacement. Artificial Heart 4, Springer-Verlag Tokyo. 349-351 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] Y.Abe, et al.: "A pulsatile total artificial heart by using precessional displacement pumps" Abstracts of the First Congress of the International Society for Rotary Blood pumps. 19 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] I.Fujimasa: "Micromachining technology and bio-medical engineering" Applied Biochemistry and Biotechnology. Vol. 41, in press. (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] I.Fujimasa, et al.: "A Notbook for Development of Micromachines" Shujunsha. 209 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1993 Final Research Report Summary
  • [Publications] 満渕 邦彦: "東京大学先端科学技術研究センター・医用電子研究施設 人工心臓開発における血栓制御の現状" 人工臓器. 23(印刷中). (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] 鎮西 恒雄: "抗血栓性材料表面へのタンパク吸着の実時間計測" 人工臓器. 23(印刷中). (1994)

    • Related Report
      1993 Annual Research Report
  • [Publications] Kou Imachi: "The jellyfish valve:a polymer membrane valve for the artificial heart" Heart Replacement:Artificial Heart 4. 41-44 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Yusuke Abe: "Reciprocal of the peripheral vascular resistance(1/R)control method for the total artificial heart" Heart Replacement:Artificial Heart 4. 349-351 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 阿部 裕輔: "新しい小型容積型連続流血液ポンプ:precessional displacement pump(PDP)" 人工臓器. 22. 683-688 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] Takashi Isoyama: "Development of a pulsatile total artificial heart using a single continuous flow pump:development of the third model" Heart Replacement:Artificial Heart 4. 287-290 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 藤正 巖: "アテネの学堂" ジャストシステム, 302 (1993)

    • Related Report
      1993 Annual Research Report
  • [Publications] 藤正 巌: "振動の場のエネルギーを使用する集積型アクチュエータの開発" Micromachine. 5. 21-26 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 藤正 巌: "序論-微小化技術の与える医療技術へのインパクト" 最新医学. 47. 735-738 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 藤正 巌: "未来の医療技術を変えるマイクロマシン" 綜合臨牀. 41. 3261-3262 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] K.Imachi: "The second and third model of the flow tfansformed pulsatile total artificial heart" ASAIO Journal. 38. 717-721 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] K.Imachi: "Fabrication of a Jellyfish valve for use in an artificial heart" ASAIO Journal. 38. 237-242 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 磯山 隆: "単一の連続流ポンプを用いた拍動流完全人工心臓システムの開発" 医用電子と生体工学. 30. 237-247 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 藤正 巌: "人工臓器1992(阿岸鉄三,桜井靖久,高野久輝編)" 中山書店, 317 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 井街 宏: "人工臓器1992(阿岸鉄三,桜井靖久,高野久輝編)" 中山書店, 317 (1992)

    • Related Report
      1992 Annual Research Report
  • [Publications] 藤正 巖: "雑音振動で動くモ-タとその応用の可能性" Micro Machine. 4. 33 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Iwao Fujimasa: "Microactuators driven by vibratory noise energy" Medical & Biological Engineering & Computing. 29(Suppl). 149 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 藤正 巖: "振動の場のエルネギ-を使用する集積型アクチュエ-タの開発" Micro Machine. 5. (1992)

    • Related Report
      1991 Annual Research Report
  • [Publications] 井街 宏: "人工心臓用Jelly fish弁の試作と性能評価" 人工臓器. 20. 789-794 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] Kou Imachi: "Direct contact method of tissue on charge coupled device for inーsitu chronic observation of microcirculation" Medical & Biological Engineering & Computing. 29(Suppl). 734 (1991)

    • Related Report
      1991 Annual Research Report
  • [Publications] 藤正 巖: "マイクロマシン開発ノ-トブック" 秀潤社, 209 (1991)

    • Related Report
      1991 Annual Research Report

URL: 

Published: 1991-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi