| Project/Area Number |
03404041
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| Research Category |
Grant-in-Aid for General Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
TAKANO Hisateru National Cardiovascular Center Research Institute, Artificial Organs, Director, 人工臓器部, 部長 (60028595)
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| Co-Investigator(Kenkyū-buntansha) |
KITOH Yoshitsugu National Cardiovascular Center Hospital, Cardiac Surgery, Director, 心臓外科, 部長
MASUZAWA Toru National Cardiovascular Center Research Institute, Artificial Organs, Research A, 人工臓器部, 室員 (40199691)
TATSUMI Eisuke National Cardiovascular Center Research Institute, Artificial Organs, Laboratory, 人工臓器部, 室長 (00216996)
NAKATANI Takeshi National Cardiovascular Center Research Institute, Biomedical Engineering, Labor, 生体工学部, 室長 (60155752)
TAENAKA Yoshiyuki National Cardiovascular Center Research Institute, Artificial Organs, Laboratory, 人工臓器部, 室長 (00142183)
川島 康生 国立循環器病センター研究所, 院長 (10028425)
木下 正之 国立循環器病センター研究所, 人工臓器部, 室員 (00183301)
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| Project Period (FY) |
1991 – 1994
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| Project Status |
Completed (Fiscal Year 1994)
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| Budget Amount *help |
¥24,400,000 (Direct Cost: ¥24,400,000)
Fiscal Year 1994: ¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 1993: ¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 1992: ¥8,300,000 (Direct Cost: ¥8,300,000)
Fiscal Year 1991: ¥10,500,000 (Direct Cost: ¥10,500,000)
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| Keywords | Left ventricular assist system / Abdominally placed blood pump / Impedance / portable control drive unit / インピーダンス法 / 制御駆動装置 / 簡易駆動装置 / 心尖脱血 / 電気インピーダンス法 / 腹壁内埋め込み型血液ポンプ / 電気インピ-ダンス |
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| Research Abstract |
We have developed an implantable left ventricular assist system (LVAS) for small sized adult patients. The pump made of segmented polyether poly-urethane was pneumatic driven diaphragm type, which was designed to be positioned in the left abdominal wall. Nine of them were sacrificed after 4 to 18 weeks in good physical condition. The electrical impedance-based monitoring and control system (Z system) was developed for adequate monitoring and automatic control. The performance of the implanted pump was well monitored and the full-fill to full-empty drive was well controlled by the Z system. In conclusion, this LVAS is promising for clinical use.
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